| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Allantoin perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Allantoin_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PM20D1 | peptidase M20 domain containing 1 | 0.148259 |
| GDA | guanine deaminase | 0.130926 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.115614 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.103611 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.103055 |
| TXNRD1 | thioredoxin reductase 1 | 0.0970186 |
| PDE10A | phosphodiesterase 10A | 0.0845514 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0825733 |
| MYOF | myoferlin | 0.0775982 |
| GRAMD1B | GRAM domain containing 1B | 0.0757014 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0732088 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.068122 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0668928 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0648371 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0624451 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0601678 |
| KYNU | kynureninase | 0.0580401 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0575618 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0551034 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0514784 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0514448 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0506869 |
| FTL | ferritin, light polypeptide | 0.0496214 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0490652 |
| ASPH | aspartate beta-hydroxylase | 0.0485864 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0483457 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0476199 |
| FLNB | filamin B, beta | 0.047194 |
| SPAG9 | sperm associated antigen 9 | 0.046416 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0455824 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0439049 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0435335 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0433791 |
| TBXT | T-box transcription factor T | 0.0433534 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0430661 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.0430152 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0425458 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | 0.0419178 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0415011 |
| NEK7 | NIMA-related kinase 7 | 0.0411066 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0406705 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.0400676 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.0389 |
| PKM | pyruvate kinase, muscle | 0.0387095 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0385042 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0373612 |
| CENPF | centromere protein F, 350/400kDa | 0.037258 |
| COL5A2 | collagen, type V, alpha 2 | 0.0372423 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0369663 |
| TMSB10 | thymosin beta 10 | 0.0368417 |
| RBM39 | RNA binding motif protein 39 | 0.0366941 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.036531 |
| LDHA | lactate dehydrogenase A | 0.0365236 |
| PCBP2 | poly(rC) binding protein 2 | 0.0364407 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0364284 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0362248 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.0356631 |
| RTN4 | reticulon 4 | 0.035279 |
| LAMA1 | laminin, alpha 1 | 0.0343533 |
| YBX3 | Y box binding protein 3 | 0.034119 |
| RPLP1 | ribosomal protein, large, P1 | 0.0341083 |
| CD109 | CD109 molecule | 0.0334312 |
| EZR | ezrin | 0.0329635 |
| COL4A5 | collagen, type IV, alpha 5 | 0.0328363 |
| MCL1 | myeloid cell leukemia 1 | 0.0322455 |
| PGK1 | phosphoglycerate kinase 1 | 0.0317034 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0314253 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0312643 |
| MKI67 | marker of proliferation Ki-67 | 0.0311964 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0308425 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0304266 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0299928 |
| FLNA | filamin A, alpha | 0.0296834 |
| RPS4X | ribosomal protein S4, X-linked | 0.029154 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0290033 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0285165 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0277602 |
| CTSC | cathepsin C | 0.0277572 |
| LAMA5 | laminin, alpha 5 | 0.027746 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0274159 |
| POTEF | POTE ankyrin domain family, member F | 0.0271566 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0270952 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0269771 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.026639 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0263907 |
| DNER | delta/notch-like EGF repeat containing | 0.0262828 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0254824 |
| WDFY2 | WD repeat and FYVE domain containing 2 | 0.0249043 |
| RPL4 | ribosomal protein L4 | 0.0246689 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0246637 |
| PHF20 | PHD finger protein 20 | 0.0243865 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0243758 |
| TNPO1 | transportin 1 | 0.0243753 |
| MYO10 | myosin X | 0.0243073 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.0242981 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0242907 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0241917 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0241348 |
| WDR43 | WD repeat domain 43 | 0.0236507 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0234352 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.164854 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.154695 |
| FN1 | fibronectin 1 | -0.0917381 |
| CDH13 | cadherin 13 | -0.0756164 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0735563 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0638814 |
| VIM | vimentin | -0.0620997 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0600458 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0548919 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0480267 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0438218 |
| NCKAP5 | NCK-associated protein 5 | -0.0419597 |
| LSAMP | limbic system-associated membrane protein | -0.0393719 |
| AUTS2 | autism susceptibility candidate 2 | -0.0381829 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0356368 |
| RPL35A | ribosomal protein L35a | -0.0297954 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.0282625 |
| PRELID2 | PRELI domain containing 2 | -0.0276328 |
| ESM1 | endothelial cell-specific molecule 1 | -0.027465 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0267358 |
| CTNND2 | catenin (cadherin-associated protein), delta 2 | -0.0265335 |
| CANX | calnexin | -0.0264099 |
| TENM3 | teneurin transmembrane protein 3 | -0.0253385 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0239673 |
| PTMA | prothymosin, alpha | -0.0235229 |
| RPS24 | ribosomal protein S24 | -0.0234786 |
| HLA-B | major histocompatibility complex, class I, B | -0.0232909 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0225905 |
| SOX6 | SRY (sex determining region Y)-box 6 | -0.0225169 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0222294 |
| PCDH15 | protocadherin-related 15 | -0.0211395 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0206675 |
| RPL7A | ribosomal protein L7a | -0.0202011 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0200146 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0198611 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.019818 |
| RPS25 | ribosomal protein S25 | -0.019671 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.019659 |
| FNIP1 | folliculin interacting protein 1 | -0.0192426 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.0191694 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0191571 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0189266 |
| DENND1A | DENN/MADD domain containing 1A | -0.0188106 |
| AGR2 | anterior gradient 2 | -0.0188092 |
| STC1 | stanniocalcin 1 | -0.0185431 |
| RANBP17 | RAN binding protein 17 | -0.018202 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0180564 |
| GOLGB1 | golgin B1 | -0.0172753 |
| NBEAL1 | neurobeachin-like 1 | -0.017059 |
| RPL34 | ribosomal protein L34 | -0.0169268 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0167739 |
| CHL1 | cell adhesion molecule L1-like | -0.0167144 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0166208 |
| SLC16A6 | solute carrier family 16, member 6 | -0.0166087 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0165922 |
| RPL36A | ribosomal protein L36a | -0.0165131 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0155951 |
| UNC5D | unc-5 homolog D (C. elegans) | -0.0155803 |
| CD44 | CD44 molecule (Indian blood group) | -0.015275 |
| PCDH9 | protocadherin 9 | -0.0152108 |
| CREM | cAMP responsive element modulator | -0.0148298 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0147773 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0147537 |
| RAD51B | RAD51 paralog B | -0.0147014 |
| GLRX | glutaredoxin (thioltransferase) | -0.0144856 |
| CTSL | cathepsin L | -0.0143212 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0142872 |
| SQSTM1 | sequestosome 1 | -0.0140887 |
| KIAA0825 | KIAA0825 | -0.0139661 |
| CALR | calreticulin | -0.0139005 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0138595 |
| TMX4 | thioredoxin-related transmembrane protein 4 | -0.01373 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0137297 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0135298 |
| RPS13 | ribosomal protein S13 | -0.0135133 |
| PRKCA | protein kinase C, alpha | -0.0134198 |
| DNAH11 | dynein, axonemal, heavy chain 11 | -0.0133871 |
| RAI14 | retinoic acid induced 14 | -0.0127942 |
| TMEM165 | transmembrane protein 165 | -0.012745 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0126906 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0122763 |
| FSTL4 | follistatin-like 4 | -0.0122437 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0122394 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0121676 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0120817 |
| HMGA2 | high mobility group AT-hook 2 | -0.012047 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0119887 |
| C9ORF153 | chromosome 9 open reading frame 153 | -0.0119139 |
| RORA | RAR-related orphan receptor A | -0.0118546 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0117682 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0117616 |
| PGM3 | phosphoglucomutase 3 | -0.0114756 |
| KCNE4 | potassium channel, voltage gated subfamily E regulatory beta subunit 4 | -0.0114708 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0114128 |
| TMSB4X | thymosin beta 4, X-linked | -0.0112411 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0110298 |
| KAT6B | K(lysine) acetyltransferase 6B | -0.0109993 |
| CUX1 | cut-like homeobox 1 | -0.0109502 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0109165 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.0107852 |
