| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Allantoin perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Allantoin_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.170987 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.088578 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0872945 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0823462 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0755761 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0706265 |
| RPS6 | ribosomal protein S6 | 0.0622306 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0556715 |
| FLNA | filamin A, alpha | 0.0551553 |
| ANXA2 | annexin A2 | 0.0531287 |
| SMAD3 | SMAD family member 3 | 0.0498376 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0486034 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0450219 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0440351 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0438485 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0426224 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0406949 |
| MYOF | myoferlin | 0.0401691 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0401259 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0378632 |
| NAV2 | neuron navigator 2 | 0.0367913 |
| SDC4 | syndecan 4 | 0.0365631 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0358061 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.035533 |
| PKM | pyruvate kinase, muscle | 0.0339204 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0338516 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0333346 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0329317 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0325127 |
| MKI67 | marker of proliferation Ki-67 | 0.0322186 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0316844 |
| SPAG9 | sperm associated antigen 9 | 0.0303511 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0292878 |
| KLF6 | Kruppel-like factor 6 | 0.0288857 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0284339 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0278953 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0277328 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.027649 |
| YBX1 | Y box binding protein 1 | 0.0274851 |
| DUSP5 | dual specificity phosphatase 5 | 0.0274557 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.027116 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0268622 |
| ARRDC3 | arrestin domain containing 3 | 0.0266003 |
| PCBP2 | poly(rC) binding protein 2 | 0.0265739 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0264132 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0263106 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.025993 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0254861 |
| AHNAK | AHNAK nucleoprotein | 0.0254823 |
| TGM2 | transglutaminase 2 | 0.0252763 |
| CENPF | centromere protein F, 350/400kDa | 0.0248522 |
| TUBB | tubulin, beta class I | 0.0238704 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0238191 |
| SYAP1 | synapse associated protein 1 | 0.0236531 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0235917 |
| LDHA | lactate dehydrogenase A | 0.0235475 |
| EZR | ezrin | 0.0235466 |
| NONO | non-POU domain containing, octamer-binding | 0.0235335 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0234954 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0234077 |
| POTEF | POTE ankyrin domain family, member F | 0.0227536 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0227439 |
| RTN4 | reticulon 4 | 0.0225108 |
| DUSP10 | dual specificity phosphatase 10 | 0.0218583 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0216171 |
| MSN | moesin | 0.0209764 |
| SEPTIN9 | septin 9 | 0.0207729 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0207701 |
| MATR3 | matrin 3 | 0.0206282 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0204999 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0204268 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0196887 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0195778 |
| TXNRD1 | thioredoxin reductase 1 | 0.0191726 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0190944 |
| FMN1 | formin 1 | 0.0189811 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0188532 |
| ZNF608 | zinc finger protein 608 | 0.0185984 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0181622 |
| TXNIP | thioredoxin interacting protein | 0.018131 |
| TAPBP | TAP binding protein (tapasin) | 0.0179304 |
| SH3BP4 | SH3-domain binding protein 4 | 0.0178511 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0178254 |
| RPS19 | ribosomal protein S19 | 0.0177341 |
| SVIL | supervillin | 0.0176269 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0174995 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0173138 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 0.0171937 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0171692 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | 0.0171536 |
| BCL9L | B-cell CLL/lymphoma 9-like | 0.0171491 |
| CTSA | cathepsin A | 0.0169722 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | 0.01684 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0167806 |
| XPO1 | exportin 1 | 0.0167635 |
| TKT | transketolase | 0.0166584 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.0165221 |
| VDAC1 | voltage-dependent anion channel 1 | 0.0164015 |
| THBS1 | thrombospondin 1 | 0.0163608 |
| RPL7A | ribosomal protein L7a | 0.016163 |
| Symbol | Name | Standardized Value |
|---|---|---|
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.136208 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.10888 |
| GLIS3 | GLIS family zinc finger 3 | -0.0964594 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0892336 |
| CDH13 | cadherin 13 | -0.0867669 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0812498 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | -0.0729796 |
| PDE10A | phosphodiesterase 10A | -0.0728978 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0680981 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0627864 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0611775 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0611695 |
| FRMPD4 | FERM and PDZ domain containing 4 | -0.0600695 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0594789 |
| HMGA2 | high mobility group AT-hook 2 | -0.0593692 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0585114 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0566468 |
| DST | dystonin | -0.0565074 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0539948 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0534053 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0531953 |
| DIAPH2 | diaphanous-related formin 2 | -0.0494021 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0472082 |
| CD44 | CD44 molecule (Indian blood group) | -0.0450241 |
| RAI14 | retinoic acid induced 14 | -0.0419243 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0419137 |
| HLA-B | major histocompatibility complex, class I, B | -0.0415756 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0403602 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0388604 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0357645 |
| INTS6 | integrator complex subunit 6 | -0.0355587 |
| EGFR | epidermal growth factor receptor | -0.0353687 |
| MMP12 | matrix metallopeptidase 12 | -0.0344301 |
| HDAC9 | histone deacetylase 9 | -0.0341304 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0328953 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0326153 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0322791 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0315821 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0315389 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0314301 |
| EFNA5 | ephrin-A5 | -0.0309419 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0308195 |
| CADM1 | cell adhesion molecule 1 | -0.0306941 |
| VIM | vimentin | -0.0299955 |
| NCKAP5 | NCK-associated protein 5 | -0.0297315 |
| NABP1 | nucleic acid binding protein 1 | -0.0296717 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.029225 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0292036 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0291829 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.0290859 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0290695 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0289665 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0288872 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.028424 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0279654 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0275459 |
| TMEM132D | transmembrane protein 132D | -0.0272131 |
| KYNU | kynureninase | -0.0270935 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.026928 |
| BNC2 | basonuclin 2 | -0.0263404 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0258817 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0255128 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0255019 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0254268 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.025394 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0246782 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0246304 |
| DPYD | dihydropyrimidine dehydrogenase | -0.024152 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0239483 |
| CANX | calnexin | -0.0238577 |
| CLMP | CXADR-like membrane protein | -0.023771 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0236194 |
| RPL9 | ribosomal protein L9 | -0.0235179 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0234261 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0232192 |
| ATXN1 | ataxin 1 | -0.0229581 |
| ZHX2 | zinc fingers and homeoboxes 2 | -0.0228661 |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 | -0.0227028 |
| ATG7 | autophagy related 7 | -0.0223939 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0221792 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.021853 |
| ARHGAP22 | Rho GTPase activating protein 22 | -0.0217529 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.0216376 |
| PGM3 | phosphoglucomutase 3 | -0.0202673 |
| HLA-E | major histocompatibility complex, class I, E | -0.0201701 |
| NDRG1 | N-myc downstream regulated 1 | -0.0199771 |
| RPL37A | ribosomal protein L37a | -0.0198711 |
| INHBA | inhibin, beta A | -0.0195562 |
| TMSB10 | thymosin beta 10 | -0.0192676 |
| EPHA6 | EPH receptor A6 | -0.019077 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 | -0.0189199 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.0188375 |
| FBXO11 | F-box protein 11 | -0.018779 |
| KAT6B | K(lysine) acetyltransferase 6B | -0.018694 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0185913 |
| C6ORF62 | chromosome 6 open reading frame 62 | -0.0185766 |
| RIGI | RNA sensor RIG-I | -0.0185443 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0184886 |
| EHBP1 | EH domain binding protein 1 | -0.0184387 |
| ZFYVE16 | zinc finger, FYVE domain containing 16 | -0.0183622 |
