Allantoin_SW 1271 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Allantoin perturbation in SW 1271 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Allantoin_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
FNDC3B fibronectin type III domain containing 3B 0.109607
LOC112694756 uncharaterized LOC112694756 0.0999605
LDHA lactate dehydrogenase A 0.0882365
DST dystonin 0.0856226
MACF1 microtubule-actin crosslinking factor 1 0.085526
PKM pyruvate kinase, muscle 0.0846669
TPT1 tumor protein, translationally-controlled 1 0.0739706
ANGPTL4 angiopoietin-like 4 0.0725172
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.0634491
ZBTB20 zinc finger and BTB domain containing 20 0.0606888
NT5E 5'-nucleotidase, ecto (CD73) 0.0594314
TMSB10 thymosin beta 10 0.0580635
FTH1 ferritin, heavy polypeptide 1 0.0557832
RSF1 remodeling and spacing factor 1 0.0503578
ATXN1 ataxin 1 0.05028
TM4SF1 transmembrane 4 L six family member 1 0.0494852
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.0476197
SVIL supervillin 0.0466178
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 0.0458841
AKAP13 A kinase (PRKA) anchor protein 13 0.0447163
FMNL2 formin-like 2 0.0435644
MBNL1 muscleblind-like splicing regulator 1 0.0432298
SDC4 syndecan 4 0.0430178
PNRC1 proline-rich nuclear receptor coactivator 1 0.0421004
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 0.0413261
CD44 CD44 molecule (Indian blood group) 0.0410084
PRKCA protein kinase C, alpha 0.04002
AHNAK AHNAK nucleoprotein 0.0399396
TRIO trio Rho guanine nucleotide exchange factor 0.0397331
BHLHE40 basic helix-loop-helix family, member e40 0.0386253
TPI1 triosephosphate isomerase 1 0.0381065
SMAD3 SMAD family member 3 0.0379064
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5 0.0378489
OSMR oncostatin M receptor 0.0376248
ZSWIM6 zinc finger, SWIM-type containing 6 0.0376105
SLC38A2 solute carrier family 38, member 2 0.0375806
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.0373947
ENO2 enolase 2 (gamma, neuronal) 0.0371865
NCOR2 nuclear receptor corepressor 2 0.0370935
SH3KBP1 SH3-domain kinase binding protein 1 0.0355951
TIMP1 TIMP metallopeptidase inhibitor 1 0.0355341
PRSS23 protease, serine, 23 0.0354994
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 0.0354142
SQSTM1 sequestosome 1 0.0345778
TXNIP thioredoxin interacting protein 0.034454
FBXL7 F-box and leucine-rich repeat protein 7 0.0343384
EXOC4 exocyst complex component 4 0.0340459
SEMA4B sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B 0.0333412
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 0.0333214
DCBLD2 discoidin, CUB and LCCL domain containing 2 0.0331948
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 0.0331126
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.0329948
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 0.0322924
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.031827
RBM25 RNA binding motif protein 25 0.0317731
HLA-B major histocompatibility complex, class I, B 0.0316299
BCAR3 breast cancer anti-estrogen resistance 3 0.0315385
MAP3K20 mitogen-activated protein kinase kinase kinase 20 0.0310681
UBE2E2 ubiquitin-conjugating enzyme E2E 2 0.0306304
ARID1B AT rich interactive domain 1B (SWI1-like) 0.0304816
RERE arginine-glutamic acid dipeptide (RE) repeats 0.0304767
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.0303219
ZMYND8 zinc finger, MYND-type containing 8 0.0299665
ZBTB38 zinc finger and BTB domain containing 38 0.0298032
LMO7 LIM domain 7 0.0295236
SSH2 slingshot protein phosphatase 2 0.0294574
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 0.0294103
LPP LIM domain containing preferred translocation partner in lipoma 0.029278
PYGL phosphorylase, glycogen, liver 0.0292772
AHNAK2 AHNAK nucleoprotein 2 0.0290303
ENO1 enolase 1, (alpha) 0.0289166
MAP1B microtubule-associated protein 1B 0.0288778
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.028165
ZNF609 zinc finger protein 609 0.028024
RBM39 RNA binding motif protein 39 0.0275654
ANKRD28 ankyrin repeat domain 28 0.0273056
NAV3 neuron navigator 3 0.02726
ACTG1 actin gamma 1 0.027245
CAVIN1 caveolae associated protein 1 0.0270899
ITGB5 integrin, beta 5 0.0269068
FLNA filamin A, alpha 0.0267594
PRRC2B proline-rich coiled-coil 2B 0.026592
EGFR epidermal growth factor receptor 0.0264949
HMGA2 high mobility group AT-hook 2 0.026373
NPEPPS aminopeptidase puromycin sensitive 0.0263239
PRR16 proline rich 16 0.0260476
VIM vimentin 0.0259956
TCF12 transcription factor 12 0.0259105
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) 0.0259045
R3HDM2 R3H domain containing 2 0.025868
B2M beta-2-microglobulin 0.0255985
NPAS2 neuronal PAS domain protein 2 0.0253867
PLEK2 pleckstrin 2 0.025157
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3 0.025156
PMEPA1 prostate transmembrane protein, androgen induced 1 0.0249461
CCDC50 coiled-coil domain containing 50 0.0247329
PHF3 PHD finger protein 3 0.0246974
SCLT1 sodium channel and clathrin linker 1 0.0245331
RNF213 ring finger protein 213 0.0244343
TAPBP TAP binding protein (tapasin) 0.0241751

decreased expression

Symbol Name Standardized Value
NAMPT nicotinamide phosphoribosyltransferase -0.0583178
SAMD4A sterile alpha motif domain containing 4A -0.0472987
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 -0.0459627
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa -0.0453538
ZC3HAV1 zinc finger CCCH-type, antiviral 1 -0.0437741
APLP2 amyloid beta (A4) precursor-like protein 2 -0.0404086
TRA2A transformer 2 alpha homolog (Drosophila) -0.0371125
GOLGA4 golgin A4 -0.0370975
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.036049
DTNA dystrobrevin, alpha -0.0349299
AHCTF1 AT hook containing transcription factor 1 -0.0334096
IGFBP3 insulin-like growth factor binding protein 3 -0.0334018
SREK1 splicing regulatory glutamine/lysine-rich protein 1 -0.0330308
FNDC3A fibronectin type III domain containing 3A -0.0328714
SEC24A SEC24 family member A -0.030872
COPB1 coatomer protein complex, subunit beta 1 -0.0303302
RBPJ recombination signal binding protein for immunoglobulin kappa J region -0.0302808
FNIP1 folliculin interacting protein 1 -0.0298833
HELZ helicase with zinc finger -0.0298154
KPNA4 karyopherin alpha 4 (importin alpha 3) -0.0297025
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0283402
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) -0.0277052
NUP58 nucleoporin 58 -0.0275314
SNX14 sorting nexin 14 -0.027363
YAP1 Yes-associated protein 1 -0.0270968
SCFD1 sec1 family domain containing 1 -0.0268046
PICALM phosphatidylinositol binding clathrin assembly protein -0.0263648
SS18 synovial sarcoma translocation, chromosome 18 -0.0259404
XPO1 exportin 1 -0.0253624
IFRD1 interferon-related developmental regulator 1 -0.0245798
NBAS neuroblastoma amplified sequence -0.0240741
BLTP1 bridge-like lipid transfer protein family member 1 -0.0240322
ADAM10 ADAM metallopeptidase domain 10 -0.024027
UBA6 ubiquitin-like modifier activating enzyme 6 -0.0239486
INSIG1 insulin induced gene 1 -0.0237575
NAP1L1 nucleosome assembly protein 1-like 1 -0.0235029
KIF20B kinesin family member 20B -0.0230809
KDM6A lysine (K)-specific demethylase 6A -0.023005
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3 -0.0230006
ENAH enabled homolog (Drosophila) -0.0229949
PDIA3 protein disulfide isomerase family A, member 3 -0.0228163
CHD1 chromodomain helicase DNA binding protein 1 -0.0227879
ANKRD37 ankyrin repeat domain 37 -0.0226122
TMEM123 transmembrane protein 123 -0.0223785
ARF4 ADP-ribosylation factor 4 -0.0223418
PIBF1 progesterone immunomodulatory binding factor 1 -0.0222861
GFPT1 glutamine--fructose-6-phosphate transaminase 1 -0.0222579
HSPA9 heat shock 70kDa protein 9 (mortalin) -0.0217059
ZBTB10 zinc finger and BTB domain containing 10 -0.02151
COG5 component of oligomeric golgi complex 5 -0.0212879
DCAF6 DDB1 and CUL4 associated factor 6 -0.0212564
SGO2 shugoshin 2 -0.0211561
FANCI Fanconi anemia, complementation group I -0.0210891
FAM13B family with sequence similarity 13, member B -0.0210818
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 -0.0210788
AP2B1 adaptor-related protein complex 2, beta 1 subunit -0.0209378
AKAP12 A kinase (PRKA) anchor protein 12 -0.0208534
MEF2A myocyte enhancer factor 2A -0.0208487
PBX3 pre-B-cell leukemia homeobox 3 -0.0208395
TBC1D15 TBC1 domain family, member 15 -0.0205462
CKAP5 cytoskeleton associated protein 5 -0.0203004
CRLS1 cardiolipin synthase 1 -0.0202511
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 -0.0202073
RPS23 ribosomal protein S23 -0.0200373
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 -0.0198965
GLG1 golgi glycoprotein 1 -0.019888
TSC22D2 TSC22 domain family, member 2 -0.0198242
ANXA5 annexin A5 -0.0198206
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -0.0198108
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae) -0.0197627
RAB6A RAB6A, member RAS oncogene family -0.0197444
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase -0.019728
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) -0.0196077
COLEC11 collectin sub-family member 11 -0.0193838
MCTP1 multiple C2 domains, transmembrane 1 -0.0193341
MED17 mediator complex subunit 17 -0.0192232
ERLEC1 endoplasmic reticulum lectin 1 -0.019195
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 -0.0191804
HBP1 HMG-box transcription factor 1 -0.0191354
LMAN1 lectin, mannose-binding, 1 -0.0187159
PGM3 phosphoglucomutase 3 -0.0185773
GBE1 glucan (1,4-alpha-), branching enzyme 1 -0.0184221
PNPLA8 patatin-like phospholipase domain containing 8 -0.018234
ARID2 AT rich interactive domain 2 (ARID, RFX-like) -0.0182015
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -0.0181335
GOLT1B golgi transport 1B -0.0181302
SND1 staphylococcal nuclease and tudor domain containing 1 -0.0180689
KTN1 kinectin 1 (kinesin receptor) -0.0180312
ZFC3H1 zinc finger, C3H1-type containing -0.0178821
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 -0.017721
SEC13 SEC13 homolog (S. cerevisiae) -0.0177069
MDM4 MDM4, p53 regulator -0.0176607
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 -0.0176317
ANLN anillin, actin binding protein -0.0175379
RNMT RNA (guanine-7-) methyltransferase -0.0175325
EIF3A eukaryotic translation initiation factor 3, subunit A -0.0174244
AVL9 AVL9 homolog (S. cerevisiase) -0.0173939
ARHGAP26 Rho GTPase activating protein 26 -0.0173642
KLHL28 kelch-like family member 28 -0.0173104
EEA1 early endosome antigen 1 -0.0172264