| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Allopurinol perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Allopurinol_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.195155 |
| PODXL | podocalyxin-like | 0.128635 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.105621 |
| COL3A1 | collagen, type III, alpha 1 | 0.103766 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.10207 |
| THBS2 | thrombospondin 2 | 0.0978787 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0939854 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0935899 |
| COL5A1 | collagen, type V, alpha 1 | 0.0932759 |
| VIM | vimentin | 0.0930689 |
| APP | amyloid beta (A4) precursor protein | 0.0919263 |
| LOXL2 | lysyl oxidase-like 2 | 0.0869132 |
| EGFR | epidermal growth factor receptor | 0.0860832 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.081535 |
| NAV2 | neuron navigator 2 | 0.080453 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0774773 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.075619 |
| LDHA | lactate dehydrogenase A | 0.0753046 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0732074 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0719252 |
| FLNB | filamin B, beta | 0.0715472 |
| ANXA2 | annexin A2 | 0.0705134 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0695087 |
| CTSB | cathepsin B | 0.0685015 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0682865 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0650514 |
| TMSB4X | thymosin beta 4, X-linked | 0.0635011 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0634699 |
| SQSTM1 | sequestosome 1 | 0.0615777 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0615574 |
| FNIP1 | folliculin interacting protein 1 | 0.0613505 |
| HDLBP | high density lipoprotein binding protein | 0.0612412 |
| CDH13 | cadherin 13 | 0.060708 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0603919 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0600919 |
| FLNA | filamin A, alpha | 0.0596266 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.056352 |
| SEPTIN9 | septin 9 | 0.0549529 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0540803 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0539227 |
| CANX | calnexin | 0.0537488 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0534204 |
| RND3 | Rho family GTPase 3 | 0.0528358 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0520023 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0507787 |
| DST | dystonin | 0.0493883 |
| TPM3 | tropomyosin 3 | 0.0493274 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0491315 |
| COL5A2 | collagen, type V, alpha 2 | 0.0486847 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0469703 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0461883 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0459745 |
| C1D | C1D nuclear receptor corepressor | 0.0458641 |
| PGK1 | phosphoglycerate kinase 1 | 0.0455947 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0455657 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0451073 |
| PLAT | plasminogen activator, tissue | 0.0450369 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0442157 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0437966 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0436884 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0431815 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0429187 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0425651 |
| CENPF | centromere protein F, 350/400kDa | 0.0425047 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0423718 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0417997 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0415783 |
| USP34 | ubiquitin specific peptidase 34 | 0.0413245 |
| GOLGA4 | golgin A4 | 0.0406442 |
| DSCAM | Down syndrome cell adhesion molecule | 0.040374 |
| CALR | calreticulin | 0.0400918 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0399388 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0398071 |
| MSN | moesin | 0.0397577 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0390482 |
| MYO9B | myosin IXB | 0.038896 |
| MAP4 | microtubule-associated protein 4 | 0.0381653 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.037489 |
| AFDN | afadin, adherens junction formation factor | 0.0371369 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0368686 |
| SBF2 | SET binding factor 2 | 0.0367978 |
| CSTB | cystatin B (stefin B) | 0.0365637 |
| KLF6 | Kruppel-like factor 6 | 0.0362422 |
| CEP350 | centrosomal protein 350kDa | 0.03594 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0358057 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.035754 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0357043 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.035668 |
| PDXK | pyridoxal (pyridoxine, vitamin B6) kinase | 0.0352985 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0352326 |
| HLA-E | major histocompatibility complex, class I, E | 0.0351314 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0350543 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0349737 |
| FSTL1 | follistatin-like 1 | 0.0345913 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0343273 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | 0.0340816 |
| LOX | lysyl oxidase | 0.0333352 |
| OPTN | optineurin | 0.0330645 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.0330162 |
| PFKP | phosphofructokinase, platelet | 0.03293 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.15596 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.139816 |
| MT2A | metallothionein 2A | -0.107604 |
| S100A10 | S100 calcium binding protein A10 | -0.0676959 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0652012 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0597244 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0581098 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0575507 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0567861 |
| B2M | beta-2-microglobulin | -0.0564736 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0516855 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0408425 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0405037 |
| MEIS2 | Meis homeobox 2 | -0.0385396 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0380816 |
| MX2 | MX dynamin-like GTPase 2 | -0.0371292 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0350289 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0339146 |
| S100A6 | S100 calcium binding protein A6 | -0.0338011 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0312884 |
| RIGI | RNA sensor RIG-I | -0.0308523 |
| RPL36 | ribosomal protein L36 | -0.0298208 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0296279 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0295944 |
| SUCNR1 | succinate receptor 1 | -0.0288432 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0285096 |
| RPLP1 | ribosomal protein, large, P1 | -0.0278643 |
| H2AC6 | H2A clustered histone 6 | -0.0274592 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0273616 |
| TXNIP | thioredoxin interacting protein | -0.0271351 |
| RPL28 | ribosomal protein L28 | -0.0251939 |
| FTL | ferritin, light polypeptide | -0.0241958 |
| PARD3 | par-3 family cell polarity regulator | -0.0237815 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.023709 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.023616 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0235937 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0235908 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0235782 |
| USP3 | ubiquitin specific peptidase 3 | -0.023495 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0231028 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0226021 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0219702 |
| SEC61G | Sec61 gamma subunit | -0.021861 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0215997 |
| SAMD9L | sterile alpha motif domain containing 9-like | -0.0205813 |
| RPL34 | ribosomal protein L34 | -0.0202097 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0201133 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0193391 |
| RPS15 | ribosomal protein S15 | -0.0192381 |
| CKAP4 | cytoskeleton-associated protein 4 | -0.0191649 |
| RPLP2 | ribosomal protein, large, P2 | -0.0191321 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0187047 |
| RPL35A | ribosomal protein L35a | -0.0186165 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0186047 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0184706 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0182926 |
| RPL35 | ribosomal protein L35 | -0.0181515 |
| DCLK2 | doublecortin-like kinase 2 | -0.0178283 |
| S100A9 | S100 calcium binding protein A9 | -0.0174172 |
| TPM1 | tropomyosin 1 (alpha) | -0.0174015 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.017168 |
| POTEF | POTE ankyrin domain family, member F | -0.0171531 |
| RRM2 | ribonucleotide reductase M2 | -0.0171194 |
| IER3 | immediate early response 3 | -0.0168256 |
| RPS14 | ribosomal protein S14 | -0.016743 |
| FAM162A | family with sequence similarity 162, member A | -0.0166106 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0163044 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | -0.0162642 |
| KCTD9 | potassium channel tetramerization domain containing 9 | -0.0161099 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0157171 |
| RPS24 | ribosomal protein S24 | -0.0156539 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0155718 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0153364 |
| RPS8 | ribosomal protein S8 | -0.0153158 |
| RPS21 | ribosomal protein S21 | -0.0153138 |
| PFN1 | profilin 1 | -0.0150983 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0150972 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0150937 |
| IFI44L | interferon-induced protein 44-like | -0.0150854 |
| RPL31 | ribosomal protein L31 | -0.0150751 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0149404 |
| S100A11 | S100 calcium binding protein A11 | -0.0147208 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.0146853 |
| MKX | mohawk homeobox | -0.0146549 |
| SPDL1 | spindle apparatus coiled-coil protein 1 | -0.0145981 |
| DEPP1 | DEPP autophagy regulator 1 | -0.0145749 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0142528 |
| RPL27 | ribosomal protein L27 | -0.0141124 |
| MB21D2 | Mab-21 domain containing 2 | -0.014109 |
| FGF13 | fibroblast growth factor 13 | -0.0139798 |
| RNF145 | ring finger protein 145 | -0.013945 |
| RPS6 | ribosomal protein S6 | -0.0139285 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0137563 |
| RPL23 | ribosomal protein L23 | -0.0135601 |
| QKI | QKI, KH domain containing, RNA binding | -0.0133379 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0132516 |
| H3-3B | H3.3 histone B | -0.0132015 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0129324 |
| LPCAT2 | lysophosphatidylcholine acyltransferase 2 | -0.0128689 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | -0.012859 |
