| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Allopurinol perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Allopurinol_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AREG | amphiregulin | 0.15702 |
| USP34 | ubiquitin specific peptidase 34 | 0.108969 |
| ANXA1 | annexin A1 | 0.0817631 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0773899 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.07568 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0663406 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0630714 |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) | 0.0545553 |
| PGK1 | phosphoglycerate kinase 1 | 0.0526574 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.050852 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0504678 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0504268 |
| TPM3 | tropomyosin 3 | 0.0497516 |
| RBM39 | RNA binding motif protein 39 | 0.0489889 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0471643 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.0460358 |
| LDHA | lactate dehydrogenase A | 0.04499 |
| EGR1 | early growth response 1 | 0.0437619 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0428698 |
| CCNL1 | cyclin L1 | 0.0416937 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0405637 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0396145 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0381663 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0380863 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0370098 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0366615 |
| BPTF | bromodomain PHD finger transcription factor | 0.0355218 |
| PNN | pinin, desmosome associated protein | 0.0341347 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0340521 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0339738 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0333317 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0330481 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.032978 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0325595 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0325195 |
| BRD2 | bromodomain containing 2 | 0.0322562 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0321224 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0320121 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0317429 |
| HMGA1 | high mobility group AT-hook 1 | 0.0317158 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0313417 |
| ATXN2 | ataxin 2 | 0.0312559 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0307725 |
| ASPH | aspartate beta-hydroxylase | 0.0306003 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.030371 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.030039 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0300168 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0299071 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0296928 |
| TBC1D32 | TBC1 domain family, member 32 | 0.0284693 |
| GOLT1A | golgi transport 1A | 0.0281602 |
| TMEM41B | transmembrane protein 41B | 0.0279856 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0279515 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.02763 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 | 0.0274734 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0274362 |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 | 0.0271181 |
| GOLGB1 | golgin B1 | 0.0267576 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0266841 |
| ATP11A | ATPase, class VI, type 11A | 0.0264613 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | 0.0264442 |
| WDR43 | WD repeat domain 43 | 0.0262054 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.025688 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0253225 |
| HEATR1 | HEAT repeat containing 1 | 0.0251881 |
| FAT1 | FAT atypical cadherin 1 | 0.0251021 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0249506 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0244499 |
| DHX40 | DEAH (Asp-Glu-Ala-His) box polypeptide 40 | 0.0241854 |
| ILF3 | interleukin enhancer binding factor 3, 90kDa | 0.0240698 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | 0.0239409 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0236651 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0234974 |
| TXNRD1 | thioredoxin reductase 1 | 0.0233599 |
| BLZF1 | basic leucine zipper nuclear factor 1 | 0.0230371 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0229562 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0229475 |
| RAB10 | RAB10, member RAS oncogene family | 0.0229343 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0227544 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0226158 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0224632 |
| RBM4 | RNA binding motif protein 4 | 0.0223613 |
| CEP350 | centrosomal protein 350kDa | 0.0223561 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0223438 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.022084 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0220806 |
| ZNF207 | zinc finger protein 207 | 0.0220057 |
| GOLIM4 | golgi integral membrane protein 4 | 0.0218383 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0216331 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.0216298 |
| PEG10 | paternally expressed 10 | 0.0216271 |
| EHBP1 | EH domain binding protein 1 | 0.0216042 |
| PSMD12 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 | 0.0216007 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0214555 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.021314 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.0212755 |
| GCG | glucagon | 0.0212363 |
| ZFYVE16 | zinc finger, FYVE domain containing 16 | 0.0211412 |
| FN1 | fibronectin 1 | 0.021137 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0211233 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.195812 |
| TMSB10 | thymosin beta 10 | -0.157274 |
| VIM | vimentin | -0.127706 |
| RPS27A | ribosomal protein S27a | -0.102364 |
| AHNAK | AHNAK nucleoprotein | -0.0987428 |
| UBC | ubiquitin C | -0.0936764 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0921679 |
| ZNF804A | zinc finger protein 804A | -0.0836477 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.0783388 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0683624 |
| RPLP1 | ribosomal protein, large, P1 | -0.0633987 |
| RPL19 | ribosomal protein L19 | -0.0625482 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0609404 |
| BCHE | butyrylcholinesterase | -0.0581339 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0570366 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0568976 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.053254 |
| RACK1 | receptor for activated C kinase 1 | -0.0525324 |
| RPS8 | ribosomal protein S8 | -0.0521907 |
| RPS29 | ribosomal protein S29 | -0.0478041 |
| NLGN1 | neuroligin 1 | -0.0458598 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0456021 |
| PCDH7 | protocadherin 7 | -0.0444461 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0440172 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0439469 |
| MGAT4C | MGAT4 family, member C | -0.0438771 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0430339 |
| MPG | N-methylpurine-DNA glycosylase | -0.0429548 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0427023 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0416696 |
| ENO1 | enolase 1, (alpha) | -0.040927 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0405716 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -0.039797 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0397396 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0395336 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.038732 |
| TENM3 | teneurin transmembrane protein 3 | -0.0365569 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0363391 |
| MYPN | myopalladin | -0.0360276 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.035291 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0348654 |
| DPYD | dihydropyrimidine dehydrogenase | -0.034428 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0343881 |
| RPS19 | ribosomal protein S19 | -0.0343834 |
| XPO1 | exportin 1 | -0.0340796 |
| DTNA | dystrobrevin, alpha | -0.0340297 |
| PTMA | prothymosin, alpha | -0.0338556 |
| TPI1 | triosephosphate isomerase 1 | -0.0338025 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.033256 |
| MMP12 | matrix metallopeptidase 12 | -0.0331609 |
| RPL23 | ribosomal protein L23 | -0.0329048 |
| RPS24 | ribosomal protein S24 | -0.0326322 |
| YBX1 | Y box binding protein 1 | -0.0326228 |
| RPL36 | ribosomal protein L36 | -0.0321386 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0315855 |
| RPL27 | ribosomal protein L27 | -0.0315544 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0313399 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | -0.0312496 |
| PDGFC | platelet derived growth factor C | -0.0311976 |
| RPS16 | ribosomal protein S16 | -0.0303868 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -0.0301795 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.030123 |
| ZFR | zinc finger RNA binding protein | -0.0300744 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0293739 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0291843 |
| RPLP2 | ribosomal protein, large, P2 | -0.0290068 |
| H1-0 | H1.0 linker histone | -0.0288392 |
| RPS2 | ribosomal protein S2 | -0.0288308 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0287682 |
| TM7SF3 | transmembrane 7 superfamily member 3 | -0.028566 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0285367 |
| RPL37 | ribosomal protein L37 | -0.0284324 |
| RPL12 | ribosomal protein L12 | -0.0282313 |
| RPS12 | ribosomal protein S12 | -0.028037 |
| RPS13 | ribosomal protein S13 | -0.0275795 |
| RTN4 | reticulon 4 | -0.0274228 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0269325 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | -0.0268696 |
| SPAG9 | sperm associated antigen 9 | -0.0264707 |
| RPL26 | ribosomal protein L26 | -0.026377 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0263087 |
| VEZT | vezatin, adherens junctions transmembrane protein | -0.0261742 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0261509 |
| RPS27 | ribosomal protein S27 | -0.0258524 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0257514 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.025737 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0254793 |
| FOXO3 | forkhead box O3 | -0.0251591 |
| USP53 | ubiquitin specific peptidase 53 | -0.0251494 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0251453 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.024958 |
| RPS20 | ribosomal protein S20 | -0.0249468 |
| UBB | ubiquitin B | -0.024899 |
| ERO1B | endoplasmic reticulum oxidoreductase 1 beta | -0.0248404 |
| TUBB6 | tubulin, beta 6 class V | -0.0245131 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | -0.0243633 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0241396 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | -0.0239112 |
| PARD3 | par-3 family cell polarity regulator | -0.0238559 |
| RTN3 | reticulon 3 | -0.023838 |
