| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Allopurinol perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Allopurinol_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.123515 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.1203 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0947605 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0867776 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0861085 |
| LPIN1 | lipin 1 | 0.0761656 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0719972 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0681327 |
| PCBP2 | poly(rC) binding protein 2 | 0.0638831 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0634317 |
| TRIB2 | tribbles pseudokinase 2 | 0.0607257 |
| COL3A1 | collagen, type III, alpha 1 | 0.0603294 |
| WDR43 | WD repeat domain 43 | 0.0595183 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | 0.0549215 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0533142 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0533088 |
| TLE4 | transducin-like enhancer of split 4 | 0.0528672 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0523979 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0510184 |
| VCL | vinculin | 0.0486329 |
| PTMA | prothymosin, alpha | 0.047985 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0477921 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0468387 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0429002 |
| APP | amyloid beta (A4) precursor protein | 0.0421129 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0417274 |
| OGA | O-GlcNAcase | 0.0416659 |
| VIM | vimentin | 0.0403116 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0398249 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0397032 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0393736 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | 0.038779 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0385058 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0384956 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0383397 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.038166 |
| SPAG9 | sperm associated antigen 9 | 0.0380711 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0379929 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0376885 |
| CENPF | centromere protein F, 350/400kDa | 0.0362569 |
| GRB2 | growth factor receptor-bound protein 2 | 0.034593 |
| SETD2 | SET domain containing 2 | 0.0343991 |
| VMP1 | vacuole membrane protein 1 | 0.0340768 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0339876 |
| POTEF | POTE ankyrin domain family, member F | 0.0339352 |
| YTHDC1 | YTH domain containing 1 | 0.0337616 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0329529 |
| KIF5B | kinesin family member 5B | 0.0328379 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0327691 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0326671 |
| ENAH | enabled homolog (Drosophila) | 0.0323135 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0317878 |
| SRSF1 | serine/arginine-rich splicing factor 1 | 0.0315938 |
| MKI67 | marker of proliferation Ki-67 | 0.0313866 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0313669 |
| XPO1 | exportin 1 | 0.0313519 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0313379 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0312941 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0312177 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | 0.0312026 |
| DPH6 | diphthamine biosynthesis 6 | 0.0310957 |
| TNRC6A | trinucleotide repeat containing 6A | 0.0309578 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0309109 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0307708 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0307082 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0306343 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0306303 |
| MED13L | mediator complex subunit 13-like | 0.0304849 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0303673 |
| MED13 | mediator complex subunit 13 | 0.0301798 |
| TPM3 | tropomyosin 3 | 0.0300534 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0299383 |
| AHCTF1 | AT hook containing transcription factor 1 | 0.0298352 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0296882 |
| PCM1 | pericentriolar material 1 | 0.0296388 |
| RBM25 | RNA binding motif protein 25 | 0.029605 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0295906 |
| ATXN2 | ataxin 2 | 0.029568 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0295011 |
| MSI2 | musashi RNA-binding protein 2 | 0.0292839 |
| USP34 | ubiquitin specific peptidase 34 | 0.0292634 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0292572 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0291319 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0290276 |
| FAM13A | family with sequence similarity 13, member A | 0.028675 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 | 0.028554 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0284327 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0283665 |
| ANKRD11 | ankyrin repeat domain 11 | 0.028303 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0281697 |
| LMNA | lamin A/C | 0.0280719 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0279638 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0278431 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0273037 |
| VEGFA | vascular endothelial growth factor A | 0.0272246 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0271869 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0270914 |
| DST | dystonin | 0.026946 |
| COL1A1 | collagen, type I, alpha 1 | 0.0268887 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.026845 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.105569 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.085596 |
| NRG1 | neuregulin 1 | -0.0836895 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0728316 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0714693 |
| LSAMP | limbic system-associated membrane protein | -0.0708453 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0641727 |
| CADM2 | cell adhesion molecule 2 | -0.0618546 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0596206 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0594239 |
| RPL35A | ribosomal protein L35a | -0.0565853 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.0563672 |
| MEIS2 | Meis homeobox 2 | -0.0519836 |
| RPL23 | ribosomal protein L23 | -0.0514971 |
| MEF2A | myocyte enhancer factor 2A | -0.0512827 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | -0.047344 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0457687 |
| SYT1 | synaptotagmin I | -0.0433456 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0425482 |
| FMN1 | formin 1 | -0.0405105 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.039237 |
| TMSB10 | thymosin beta 10 | -0.0391871 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0388839 |
| UNC5C | unc-5 homolog C (C. elegans) | -0.0383258 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0375208 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0367721 |
| HAND2 | heart and neural crest derivatives expressed 2 | -0.0366913 |
| ATRNL1 | attractin-like 1 | -0.0365071 |
| DIAPH2 | diaphanous-related formin 2 | -0.0360285 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0352047 |
| RPLP1 | ribosomal protein, large, P1 | -0.0349025 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.034578 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0345141 |
| NREP | neuronal regeneration related protein | -0.0338732 |
| CRH | corticotropin releasing hormone | -0.0331707 |
| ST6GALNAC3 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 | -0.0329827 |
| PLAT | plasminogen activator, tissue | -0.0328794 |
| ITGA1 | integrin, alpha 1 | -0.0327215 |
| AHR | aryl hydrocarbon receptor | -0.0327192 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0324067 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0323726 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0322133 |
| DKK2 | dickkopf WNT signaling pathway inhibitor 2 | -0.032185 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0319608 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.031018 |
| ENO1 | enolase 1, (alpha) | -0.0306403 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0303456 |
| GNG2 | guanine nucleotide binding protein (G protein), gamma 2 | -0.030074 |
| PRKD1 | protein kinase D1 | -0.0296791 |
| KLHL13 | kelch-like family member 13 | -0.0295065 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0293638 |
| NRP1 | neuropilin 1 | -0.0291957 |
| STC1 | stanniocalcin 1 | -0.0290334 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.028789 |
| NDRG1 | N-myc downstream regulated 1 | -0.0283743 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0283643 |
| ZNF804A | zinc finger protein 804A | -0.0279193 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0278689 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0277039 |
| DNM3 | dynamin 3 | -0.0275188 |
| RPS24 | ribosomal protein S24 | -0.0274116 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0272681 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0272593 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0271905 |
| RPL38 | ribosomal protein L38 | -0.0266605 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0265368 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0264177 |
| IER3 | immediate early response 3 | -0.0261934 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.025534 |
| COL18A1 | collagen, type XVIII, alpha 1 | -0.0254676 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0253648 |
| TOX | thymocyte selection-associated high mobility group box | -0.025089 |
| TBC1D19 | TBC1 domain family, member 19 | -0.0249729 |
| EPHA3 | EPH receptor A3 | -0.0242983 |
| FRMD4A | FERM domain containing 4A | -0.0241437 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0240686 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0240148 |
| RPS21 | ribosomal protein S21 | -0.0238006 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0234997 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | -0.0226047 |
| FAM162A | family with sequence similarity 162, member A | -0.0216703 |
| RANBP17 | RAN binding protein 17 | -0.0215505 |
| H1-0 | H1.0 linker histone | -0.0211581 |
| PCDH9 | protocadherin 9 | -0.0210684 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0210519 |
| PLPP1 | phospholipid phosphatase 1 | -0.0206903 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0203426 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0201956 |
| RPS5 | ribosomal protein S5 | -0.0200749 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0200119 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0199543 |
| KCNIP4 | Kv channel interacting protein 4 | -0.0197872 |
| PTEN | phosphatase and tensin homolog | -0.0197665 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0197216 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0195249 |
| EPHA6 | EPH receptor A6 | -0.0195077 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0194239 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0193769 |
| SIK2 | salt-inducible kinase 2 | -0.0191368 |
| DENND1A | DENN/MADD domain containing 1A | -0.0190948 |
