| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Allopurinol perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Allopurinol_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.23418 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.135956 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.117159 |
| EZR | ezrin | 0.11359 |
| DSCAM | Down syndrome cell adhesion molecule | 0.106574 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0932608 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0837035 |
| ANXA2 | annexin A2 | 0.0827188 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0826372 |
| MYO1E | myosin IE | 0.0777287 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0742644 |
| TMC5 | transmembrane channel-like 5 | 0.0693653 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0683994 |
| IRF1 | interferon regulatory factor 1 | 0.0679382 |
| GOLGB1 | golgin B1 | 0.0641036 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0630262 |
| EGR1 | early growth response 1 | 0.0628205 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0623345 |
| ASPH | aspartate beta-hydroxylase | 0.0564236 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0558931 |
| PGK1 | phosphoglycerate kinase 1 | 0.0557844 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0554732 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0538471 |
| INTS6 | integrator complex subunit 6 | 0.0530078 |
| DST | dystonin | 0.0521673 |
| NCKAP5 | NCK-associated protein 5 | 0.0520255 |
| JUN | jun proto-oncogene | 0.0519159 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0515366 |
| STK24 | serine/threonine kinase 24 | 0.050047 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.049276 |
| PHF3 | PHD finger protein 3 | 0.0490799 |
| CCNL1 | cyclin L1 | 0.0488652 |
| EFNB2 | ephrin-B2 | 0.048382 |
| RAD51B | RAD51 paralog B | 0.0480631 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0456174 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0454908 |
| PLSCR1 | phospholipid scramblase 1 | 0.0452663 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0452466 |
| PHACTR4 | phosphatase and actin regulator 4 | 0.0448935 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0419461 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0401732 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0400151 |
| ZNF292 | zinc finger protein 292 | 0.0396427 |
| CDHR2 | cadherin-related family member 2 | 0.0383136 |
| SQSTM1 | sequestosome 1 | 0.0380416 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0374705 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0374244 |
| VMP1 | vacuole membrane protein 1 | 0.0371185 |
| TJP1 | tight junction protein 1 | 0.0359477 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.035625 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0354877 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0354673 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.035059 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0344722 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0343479 |
| DSPP | dentin sialophosphoprotein | 0.0339469 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.033905 |
| DIAPH1 | diaphanous-related formin 1 | 0.0338435 |
| FAT1 | FAT atypical cadherin 1 | 0.0333307 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0329008 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0326549 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0320094 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0316844 |
| MCL1 | myeloid cell leukemia 1 | 0.031566 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0312043 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0311856 |
| VEGFA | vascular endothelial growth factor A | 0.0308109 |
| UBAP1 | ubiquitin associated protein 1 | 0.030782 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0307797 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0307796 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0303514 |
| RRBP1 | ribosome binding protein 1 | 0.0303322 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.0301787 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0300948 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0300859 |
| OARD1 | O-acyl-ADP-ribose deacylase 1 | 0.030038 |
| HM13 | histocompatibility (minor) 13 | 0.0299988 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0299427 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0298611 |
| ERBIN | erbb2 interacting protein | 0.0298031 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0295442 |
| ITPKC | inositol-trisphosphate 3-kinase C | 0.0295195 |
| DUSP10 | dual specificity phosphatase 10 | 0.029327 |
| MX1 | MX dynamin-like GTPase 1 | 0.0292914 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0291622 |
| MEIS2 | Meis homeobox 2 | 0.029125 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0291022 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0290589 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0290281 |
| LDHA | lactate dehydrogenase A | 0.028795 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0285389 |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.0282142 |
| VCL | vinculin | 0.0278563 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0277692 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0274849 |
| CALU | calumenin | 0.0274755 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0273222 |
| ATXN1 | ataxin 1 | 0.0272683 |
| MAP7 | microtubule-associated protein 7 | 0.027098 |
| BPTF | bromodomain PHD finger transcription factor | 0.0270077 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RNF149 | ring finger protein 149 | -0.0504809 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0388487 |
| LYZ | lysozyme | -0.0315193 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0302078 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0296961 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0294102 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | -0.0293411 |
| H1-0 | H1.0 linker histone | -0.0290693 |
| MSI2 | musashi RNA-binding protein 2 | -0.0284051 |
| TMSB10 | thymosin beta 10 | -0.0273022 |
| WDR45B | WD repeat domain 45B | -0.0258801 |
| RNF43 | ring finger protein 43 | -0.0244009 |
| RPLP1 | ribosomal protein, large, P1 | -0.0239511 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0238847 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0237257 |
| LCN2 | lipocalin 2 | -0.0237245 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | -0.0236888 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.023626 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.0235127 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0223437 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0222301 |
| USPL1 | ubiquitin specific peptidase like 1 | -0.0217586 |
| TSC22D2 | TSC22 domain family, member 2 | -0.021629 |
| FDPS | farnesyl diphosphate synthase | -0.0213188 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0207042 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0198672 |
| TXNIP | thioredoxin interacting protein | -0.0197295 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0196781 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0193795 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0193203 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.018992 |
| SORBS1 | sorbin and SH3 domain containing 1 | -0.0187551 |
| GNAS | GNAS complex locus | -0.018544 |
| GRAMD2B | GRAM domain containing 2B | -0.0184665 |
| NPSR1 | neuropeptide S receptor 1 | -0.0182497 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0180919 |
| XAF1 | XIAP associated factor 1 | -0.0179878 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0177129 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0175885 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0173018 |
| MT2A | metallothionein 2A | -0.0172388 |
| SFXN1 | sideroflexin 1 | -0.0170988 |
| PRKCA | protein kinase C, alpha | -0.0166882 |
| H2AC6 | H2A clustered histone 6 | -0.0164188 |
| SRP54 | signal recognition particle 54kDa | -0.016356 |
| EXOC1 | exocyst complex component 1 | -0.0162791 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | -0.0161319 |
| RARS1 | arginyl-tRNA synthetase 1 | -0.0158707 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.015394 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0147476 |
| ABHD2 | abhydrolase domain containing 2 | -0.0146843 |
| RPL38 | ribosomal protein L38 | -0.0145808 |
| RPS8 | ribosomal protein S8 | -0.0143837 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0142968 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0141689 |
| RPL35A | ribosomal protein L35a | -0.013992 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.013934 |
| LNX2 | ligand of numb-protein X 2 | -0.0138987 |
| DEK | DEK proto-oncogene | -0.0138053 |
| SLC11A2 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 | -0.0136572 |
| TNS4 | tensin 4 | -0.0133552 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0133089 |
| NIPSNAP2 | nipsnap homolog 2 | -0.0131565 |
| PRPF4B | pre-mRNA processing factor 4B | -0.0131226 |
| ARAP1 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 | -0.0128858 |
| RPS19 | ribosomal protein S19 | -0.0125103 |
| VPS36 | vacuolar protein sorting 36 homolog (S. cerevisiae) | -0.0124014 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0123088 |
| MEF2A | myocyte enhancer factor 2A | -0.0122978 |
| MXD1 | MAX dimerization protein 1 | -0.0120984 |
| RPL34 | ribosomal protein L34 | -0.0119821 |
| HMGB1 | high mobility group box 1 | -0.0119232 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0117486 |
| S100A9 | S100 calcium binding protein A9 | -0.0116243 |
| AGR2 | anterior gradient 2 | -0.0116007 |
| TFF3 | trefoil factor 3 (intestinal) | -0.0114976 |
| EPB41L4B | erythrocyte membrane protein band 4.1 like 4B | -0.0114584 |
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 | -0.0113213 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.011305 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0112911 |
| RPS21 | ribosomal protein S21 | -0.0112576 |
| TBCA | tubulin folding cofactor A | -0.0112564 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.0112097 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0111948 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0111334 |
| PSMD5 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 | -0.0111266 |
| EPHB2 | EPH receptor B2 | -0.0109006 |
| GPR107 | G protein-coupled receptor 107 | -0.0108856 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0108323 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0107977 |
| NF1 | neurofibromin 1 | -0.0107781 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0107388 |
| TBPL1 | TBP-like 1 | -0.0106783 |
| UBAC2 | UBA domain containing 2 | -0.0106319 |
| TENT2 | terminal nucleotidyltransferase 2 | -0.0106128 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0104353 |
| RPL23 | ribosomal protein L23 | -0.010431 |
| SSH2 | slingshot protein phosphatase 2 | -0.0104213 |
| SLC2A12 | solute carrier family 2 (facilitated glucose transporter), member 12 | -0.010395 |
| S100A6 | S100 calcium binding protein A6 | -0.010315 |
