| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Allopurinol perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Allopurinol_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VEGFA | vascular endothelial growth factor A | 0.146933 |
| COL6A3 | collagen, type VI, alpha 3 | 0.128925 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.12712 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.11829 |
| FN1 | fibronectin 1 | 0.109156 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0948038 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0926909 |
| CDH13 | cadherin 13 | 0.0908616 |
| GOLGA4 | golgin A4 | 0.0779723 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0748589 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0710238 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0671754 |
| ATP13A3 | ATPase type 13A3 | 0.0659316 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0657055 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0651919 |
| COL5A1 | collagen, type V, alpha 1 | 0.0633789 |
| PTK2 | protein tyrosine kinase 2 | 0.0620538 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0619787 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0589162 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0560324 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0552965 |
| NDRG1 | N-myc downstream regulated 1 | 0.0545309 |
| PDE10A | phosphodiesterase 10A | 0.0490903 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0489463 |
| PLEC | plectin | 0.045251 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0432209 |
| EGFR | epidermal growth factor receptor | 0.0431906 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0431197 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0427426 |
| CADM1 | cell adhesion molecule 1 | 0.0423979 |
| RAB2A | RAB2A, member RAS oncogene family | 0.0406698 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0405922 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0403999 |
| GOLGB1 | golgin B1 | 0.0401232 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0394179 |
| APP | amyloid beta (A4) precursor protein | 0.0393369 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0390774 |
| EFNA5 | ephrin-A5 | 0.0384351 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0383286 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0382594 |
| TMSB4X | thymosin beta 4, X-linked | 0.0380329 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0377472 |
| CALU | calumenin | 0.0375336 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0368325 |
| NAV2 | neuron navigator 2 | 0.036698 |
| RASA2 | RAS p21 protein activator 2 | 0.036088 |
| FMNL2 | formin-like 2 | 0.0355609 |
| COPA | coatomer protein complex, subunit alpha | 0.0352853 |
| ANXA1 | annexin A1 | 0.0343437 |
| FLNA | filamin A, alpha | 0.0340009 |
| MSN | moesin | 0.0339695 |
| CLINT1 | clathrin interactor 1 | 0.0336018 |
| MYO9B | myosin IXB | 0.032838 |
| FLNB | filamin B, beta | 0.0325742 |
| RBM39 | RNA binding motif protein 39 | 0.0321652 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0320873 |
| COL3A1 | collagen, type III, alpha 1 | 0.0316234 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0310376 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0306348 |
| CMIP | c-Maf inducing protein | 0.0305886 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0305563 |
| FNIP1 | folliculin interacting protein 1 | 0.030461 |
| PCBP2 | poly(rC) binding protein 2 | 0.0304351 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0302465 |
| TNS1 | tensin 1 | 0.0296654 |
| ATXN1 | ataxin 1 | 0.0293189 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0291242 |
| VCAN | versican | 0.029012 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0286969 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0282946 |
| XRN2 | 5'-3' exoribonuclease 2 | 0.0282112 |
| STC1 | stanniocalcin 1 | 0.0281885 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0281743 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0279 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0277723 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.0277062 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0275684 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0274882 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0273901 |
| MATR3 | matrin 3 | 0.0271763 |
| SFPQ | splicing factor proline/glutamine-rich | 0.027054 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0269044 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0267866 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0267758 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0267431 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0263543 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0262322 |
| CLTC | clathrin, heavy chain (Hc) | 0.0261299 |
| RYK | receptor-like tyrosine kinase | 0.0259032 |
| NKTR | natural killer cell triggering receptor | 0.0258771 |
| SEPTIN9 | septin 9 | 0.025823 |
| FAT1 | FAT atypical cadherin 1 | 0.0253761 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0253148 |
| CCNY | cyclin Y | 0.0250703 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0250435 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0250382 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0248939 |
| MAP4 | microtubule-associated protein 4 | 0.0248454 |
| PRELID2 | PRELI domain containing 2 | 0.0246879 |
| TMEM165 | transmembrane protein 165 | 0.0246845 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.231265 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.13363 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.111363 |
| VIM | vimentin | -0.0785067 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0754663 |
| TMSB10 | thymosin beta 10 | -0.0718185 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0669506 |
| MT2A | metallothionein 2A | -0.0628139 |
| IER3 | immediate early response 3 | -0.0516458 |
| CD44 | CD44 molecule (Indian blood group) | -0.048454 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0461989 |
| FTL | ferritin, light polypeptide | -0.0408751 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | -0.0387113 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0386413 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0376871 |
| RIGI | RNA sensor RIG-I | -0.0368308 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0366933 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0364272 |
| PALLD | palladin, cytoskeletal associated protein | -0.0357298 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0323278 |
| COL1A1 | collagen, type I, alpha 1 | -0.0288548 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.028775 |
| FAM162A | family with sequence similarity 162, member A | -0.0270362 |
| HLA-B | major histocompatibility complex, class I, B | -0.0269556 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0251515 |
| INHBA | inhibin, beta A | -0.0251326 |
| H1-0 | H1.0 linker histone | -0.0246537 |
| S100A9 | S100 calcium binding protein A9 | -0.024647 |
| EGR1 | early growth response 1 | -0.024115 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0240915 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.02395 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.023444 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0228708 |
| HMGA2 | high mobility group AT-hook 2 | -0.0227934 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0223488 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0219424 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0212507 |
| S100A6 | S100 calcium binding protein A6 | -0.0211878 |
| B2M | beta-2-microglobulin | -0.0208998 |
| ENO1 | enolase 1, (alpha) | -0.0207907 |
| RAD21 | RAD21 homolog (S. pombe) | -0.020251 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0201809 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0198327 |
| RPL28 | ribosomal protein L28 | -0.0195245 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.0190833 |
| AHNAK | AHNAK nucleoprotein | -0.0189593 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0188315 |
| S100A10 | S100 calcium binding protein A10 | -0.0186843 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0185863 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.018376 |
| RPLP1 | ribosomal protein, large, P1 | -0.018214 |
| NREP | neuronal regeneration related protein | -0.0178563 |
| LOX | lysyl oxidase | -0.0175772 |
| HLA-A | major histocompatibility complex, class I, A | -0.0173166 |
| ECE1 | endothelin converting enzyme 1 | -0.0166831 |
| KLF6 | Kruppel-like factor 6 | -0.016617 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.0166031 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0165698 |
| VEGFC | vascular endothelial growth factor C | -0.016528 |
| PIEZO2 | piezo-type mechanosensitive ion channel component 2 | -0.0161632 |
| UBC | ubiquitin C | -0.0161491 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0157722 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0157493 |
| EBF1 | early B-cell factor 1 | -0.0156988 |
| SQSTM1 | sequestosome 1 | -0.0156894 |
| VCL | vinculin | -0.0156157 |
| COL1A2 | collagen, type I, alpha 2 | -0.0155094 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0153409 |
| AHR | aryl hydrocarbon receptor | -0.0153143 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0151264 |
| MAP1B | microtubule-associated protein 1B | -0.0150979 |
| JAK2 | Janus kinase 2 | -0.0149644 |
| TPI1 | triosephosphate isomerase 1 | -0.014953 |
| RPS8 | ribosomal protein S8 | -0.0148769 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0147337 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0146941 |
| RPS24 | ribosomal protein S24 | -0.0141246 |
| HMGB1 | high mobility group box 1 | -0.0137476 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0134876 |
| TENM1 | teneurin transmembrane protein 1 | -0.0134307 |
| HMGA1 | high mobility group AT-hook 1 | -0.0133833 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0131238 |
| IL6ST | interleukin 6 signal transducer | -0.0129809 |
| HDAC9 | histone deacetylase 9 | -0.0128744 |
| PRSS23 | protease, serine, 23 | -0.0128392 |
| RPL12 | ribosomal protein L12 | -0.0127928 |
| NABP1 | nucleic acid binding protein 1 | -0.0127139 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0127118 |
| RPL19 | ribosomal protein L19 | -0.0127079 |
| RPLP2 | ribosomal protein, large, P2 | -0.0127066 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0126606 |
| TPM1 | tropomyosin 1 (alpha) | -0.0126324 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0125902 |
| RPS19 | ribosomal protein S19 | -0.0123772 |
| LIMA1 | LIM domain and actin binding 1 | -0.0122694 |
| KIAA1217 | KIAA1217 | -0.0122264 |
| FSTL1 | follistatin-like 1 | -0.0121981 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0120178 |
| ACTG1 | actin gamma 1 | -0.0118245 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0115675 |
