| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Allopurinol perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Allopurinol_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TRIO | trio Rho guanine nucleotide exchange factor | 0.125941 |
| NDRG1 | N-myc downstream regulated 1 | 0.117807 |
| MEF2A | myocyte enhancer factor 2A | 0.108972 |
| ANXA1 | annexin A1 | 0.105009 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0804951 |
| PGK1 | phosphoglycerate kinase 1 | 0.0688314 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0644248 |
| MTSS1 | metastasis suppressor 1 | 0.0613979 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0584671 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.057809 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0572931 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0565457 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0561802 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0557294 |
| EZR | ezrin | 0.0541616 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0535964 |
| ANXA2 | annexin A2 | 0.0516052 |
| PODXL | podocalyxin-like | 0.0502758 |
| LDHA | lactate dehydrogenase A | 0.0500174 |
| KRT17 | keratin 17, type I | 0.0497418 |
| SPAG9 | sperm associated antigen 9 | 0.0457767 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.045744 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0450302 |
| SQLE | squalene epoxidase | 0.0448554 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0448377 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0445757 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.04414 |
| SLK | STE20-like kinase | 0.0433162 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0421397 |
| KRT6A | keratin 6A, type II | 0.0420433 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0420204 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0403257 |
| FLNA | filamin A, alpha | 0.0393357 |
| MYOF | myoferlin | 0.0378062 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0376864 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0376248 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0374282 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0373337 |
| GOLGA4 | golgin A4 | 0.0371503 |
| DSTN | destrin (actin depolymerizing factor) | 0.0363278 |
| PTMA | prothymosin, alpha | 0.0360018 |
| ARRDC3 | arrestin domain containing 3 | 0.0354823 |
| SUCO | SUN domain containing ossification factor | 0.0353123 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0349915 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0348678 |
| NAV2 | neuron navigator 2 | 0.0344864 |
| PTK2 | protein tyrosine kinase 2 | 0.0344839 |
| CALR | calreticulin | 0.0344188 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0342871 |
| VEGFA | vascular endothelial growth factor A | 0.0342613 |
| ADM | adrenomedullin | 0.033915 |
| OGA | O-GlcNAcase | 0.0338357 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.0334546 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0331095 |
| NUP58 | nucleoporin 58 | 0.0322835 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.032165 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | 0.0320664 |
| TPM3 | tropomyosin 3 | 0.0320564 |
| RLF | rearranged L-myc fusion | 0.031814 |
| SQSTM1 | sequestosome 1 | 0.0315639 |
| CANX | calnexin | 0.0314632 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | 0.0313445 |
| KRT14 | keratin 14, type I | 0.0302912 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0295337 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0294743 |
| COPA | coatomer protein complex, subunit alpha | 0.0294197 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0289469 |
| ENO1 | enolase 1, (alpha) | 0.0286035 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0282745 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0277254 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0276136 |
| RNF145 | ring finger protein 145 | 0.0273777 |
| TOP1 | topoisomerase (DNA) I | 0.0273701 |
| QKI | QKI, KH domain containing, RNA binding | 0.0272895 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0271243 |
| PLS3 | plastin 3 | 0.0265507 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0263554 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | 0.0263096 |
| FAM13A | family with sequence similarity 13, member A | 0.026207 |
| RND3 | Rho family GTPase 3 | 0.0258865 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.025706 |
| SLMAP | sarcolemma associated protein | 0.0256595 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | 0.0254757 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0251664 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.024986 |
| HELZ | helicase with zinc finger | 0.0249745 |
| ZNF292 | zinc finger protein 292 | 0.0249492 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0249073 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0248894 |
| INSIG2 | insulin induced gene 2 | 0.0245463 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0245278 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0244642 |
| CDC73 | cell division cycle 73 | 0.0244497 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0244441 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0243599 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0240807 |
| ANLN | anillin, actin binding protein | 0.0239186 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0238009 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.023779 |
| PLEC | plectin | 0.0232702 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.159905 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.118016 |
| FOXO1 | forkhead box O1 | -0.0789091 |
| BCL2L1 | BCL2-like 1 | -0.0721203 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0717487 |
| RPS21 | ribosomal protein S21 | -0.0655935 |
| OSMR | oncostatin M receptor | -0.0574765 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0568077 |
| FOXP1 | forkhead box P1 | -0.0545156 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0530368 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0501987 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.04657 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.042547 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0387097 |
| NRG1 | neuregulin 1 | -0.0384975 |
| TMSB10 | thymosin beta 10 | -0.0378982 |
| PLAT | plasminogen activator, tissue | -0.0378509 |
| MECOM | MDS1 and EVI1 complex locus | -0.0378469 |
| AHNAK | AHNAK nucleoprotein | -0.0377326 |
| NEK7 | NIMA-related kinase 7 | -0.0371755 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | -0.0361671 |
| AOPEP | aminopeptidase O (putative) | -0.035826 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0355057 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0327955 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | -0.0321802 |
| SLC45A4 | solute carrier family 45, member 4 | -0.0316646 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | -0.0314653 |
| SMYD3 | SET and MYND domain containing 3 | -0.0301958 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0297423 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0296503 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.0293121 |
| MT2A | metallothionein 2A | -0.0286875 |
| RIN2 | Ras and Rab interactor 2 | -0.0286637 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0282323 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0280451 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | -0.0275515 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0268569 |
| LUZP1 | leucine zipper protein 1 | -0.0267096 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.0266486 |
| HLA-B | major histocompatibility complex, class I, B | -0.0266432 |
| B2M | beta-2-microglobulin | -0.0265377 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0261854 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0252384 |
| EFNA5 | ephrin-A5 | -0.0252305 |
| RPS24 | ribosomal protein S24 | -0.0250298 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0242137 |
| EXOC6B | exocyst complex component 6B | -0.0239966 |
| RPL35A | ribosomal protein L35a | -0.0239216 |
| METTL15 | methyltransferase like 15 | -0.0237734 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0222748 |
| RPLP2 | ribosomal protein, large, P2 | -0.0220333 |
| C4BPB | complement component 4 binding protein, beta | -0.0219615 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0218896 |
| DUSP6 | dual specificity phosphatase 6 | -0.0218739 |
| RPLP1 | ribosomal protein, large, P1 | -0.0218132 |
| MEIS2 | Meis homeobox 2 | -0.0217931 |
| ANKRD12 | ankyrin repeat domain 12 | -0.021586 |
| CNTNAP3 | contactin associated protein-like 3 | -0.0214584 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0212758 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0212303 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0211459 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0211327 |
| SEPTIN9 | septin 9 | -0.0209612 |
| RPS8 | ribosomal protein S8 | -0.0207912 |
| RPS19 | ribosomal protein S19 | -0.0202559 |
| TXNRD1 | thioredoxin reductase 1 | -0.0202362 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0202198 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0201655 |
| SULF1 | sulfatase 1 | -0.0198733 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0197241 |
| CMIP | c-Maf inducing protein | -0.019482 |
| DUSP4 | dual specificity phosphatase 4 | -0.0194455 |
| ITGA6 | integrin, alpha 6 | -0.0191847 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0190418 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | -0.0189501 |
| SOX7 | SRY (sex determining region Y)-box 7 | -0.0188901 |
| PALLD | palladin, cytoskeletal associated protein | -0.0187996 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 | -0.0187677 |
| EGR1 | early growth response 1 | -0.0186861 |
| SETX | senataxin | -0.0186707 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0185069 |
| RPL34 | ribosomal protein L34 | -0.0184559 |
| PRELID2 | PRELI domain containing 2 | -0.0184003 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0183714 |
| RASAL2 | RAS protein activator like 2 | -0.0181069 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0180838 |
| BPTF | bromodomain PHD finger transcription factor | -0.0180198 |
| VCL | vinculin | -0.018013 |
| ACTG1 | actin gamma 1 | -0.0179175 |
| NDE1 | nudE neurodevelopment protein 1 | -0.0177262 |
| EHBP1 | EH domain binding protein 1 | -0.0173104 |
| S100A10 | S100 calcium binding protein A10 | -0.0172327 |
| RPL12 | ribosomal protein L12 | -0.0172087 |
| TJP1 | tight junction protein 1 | -0.0172029 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0171135 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0168823 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0168256 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | -0.0167894 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0167611 |
| TNS4 | tensin 4 | -0.0166323 |
