| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Allopurinol perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Allopurinol_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF2 | eukaryotic translation elongation factor 2 | 0.166749 |
| FAT1 | FAT atypical cadherin 1 | 0.133972 |
| DSCAM | Down syndrome cell adhesion molecule | 0.130436 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | 0.129666 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.123954 |
| EZR | ezrin | 0.118173 |
| VEGFA | vascular endothelial growth factor A | 0.116856 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.116128 |
| LMO7 | LIM domain 7 | 0.113014 |
| LDHA | lactate dehydrogenase A | 0.112483 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.103439 |
| DSPP | dentin sialophosphoprotein | 0.0916784 |
| ANXA1 | annexin A1 | 0.083698 |
| ITGA6 | integrin, alpha 6 | 0.0815907 |
| TXNIP | thioredoxin interacting protein | 0.0765079 |
| FAM13A | family with sequence similarity 13, member A | 0.0713325 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0633935 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0627783 |
| PCBP2 | poly(rC) binding protein 2 | 0.0612801 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0610633 |
| PGK1 | phosphoglycerate kinase 1 | 0.0590637 |
| GOLGA4 | golgin A4 | 0.0572037 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0561826 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0556855 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0544267 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0542072 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0535996 |
| KRT8 | keratin 8, type II | 0.0517491 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.051615 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0512349 |
| KIF5B | kinesin family member 5B | 0.0510015 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0502204 |
| PTEN | phosphatase and tensin homolog | 0.0495758 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0490149 |
| NDRG1 | N-myc downstream regulated 1 | 0.0481778 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0476191 |
| EMP1 | epithelial membrane protein 1 | 0.0475415 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0458102 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0457562 |
| ATXN1 | ataxin 1 | 0.045752 |
| ASPH | aspartate beta-hydroxylase | 0.0457501 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0456447 |
| TMSB4X | thymosin beta 4, X-linked | 0.0447278 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0437975 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0437044 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.042357 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0422607 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0422209 |
| EREG | epiregulin | 0.0417168 |
| ANXA2 | annexin A2 | 0.0416731 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0412837 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0396163 |
| EHF | ets homologous factor | 0.039314 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0393125 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0391387 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0390468 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0389908 |
| TRIM2 | tripartite motif containing 2 | 0.0389169 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0388361 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0387844 |
| AREG | amphiregulin | 0.0385904 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0381979 |
| RNF145 | ring finger protein 145 | 0.0374481 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0368409 |
| KRT18 | keratin 18, type I | 0.036617 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.036593 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0361239 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0359557 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0359447 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.035867 |
| TXNRD1 | thioredoxin reductase 1 | 0.0357202 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.035664 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | 0.0354808 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0353655 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0352714 |
| USP34 | ubiquitin specific peptidase 34 | 0.0351301 |
| TPM3 | tropomyosin 3 | 0.035012 |
| USP6NL | USP6 N-terminal like | 0.0348035 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0344866 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0343684 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0342573 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0342018 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.033406 |
| VMP1 | vacuole membrane protein 1 | 0.0333685 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0332076 |
| TPD52 | tumor protein D52 | 0.0328359 |
| BRD2 | bromodomain containing 2 | 0.0326053 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0324509 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0321211 |
| NDFIP2 | Nedd4 family interacting protein 2 | 0.0320631 |
| PNN | pinin, desmosome associated protein | 0.0320014 |
| CCNL1 | cyclin L1 | 0.0319938 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0319902 |
| MED13 | mediator complex subunit 13 | 0.0317943 |
| SPAG9 | sperm associated antigen 9 | 0.0316987 |
| FHL2 | four and a half LIM domains 2 | 0.0316359 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | 0.0315467 |
| CLCN3 | chloride channel, voltage-sensitive 3 | 0.0313568 |
| SHROOM3 | shroom family member 3 | 0.0312008 |
| OGA | O-GlcNAcase | 0.0311697 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NPSR1 | neuropeptide S receptor 1 | -0.170262 |
| TMSB10 | thymosin beta 10 | -0.142964 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.125197 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.119315 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.106352 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0852291 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.084169 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0838679 |
| RPS6 | ribosomal protein S6 | -0.077703 |
| RPL35A | ribosomal protein L35a | -0.0641736 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0633927 |
| S100A6 | S100 calcium binding protein A6 | -0.0532635 |
| RPLP1 | ribosomal protein, large, P1 | -0.0524858 |
| RPS24 | ribosomal protein S24 | -0.0481094 |
| RPS8 | ribosomal protein S8 | -0.0479818 |
| ACTG1 | actin gamma 1 | -0.0479036 |
| RPL34 | ribosomal protein L34 | -0.0475024 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0473235 |
| GPHN | gephyrin | -0.0461708 |
| AHNAK | AHNAK nucleoprotein | -0.0419062 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0408611 |
| FHIT | fragile histidine triad | -0.0404494 |
| AGR2 | anterior gradient 2 | -0.0376907 |
| PTMA | prothymosin, alpha | -0.0371426 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0357454 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0353555 |
| PRSS3 | protease, serine, 3 | -0.0346815 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0335997 |
| TNS4 | tensin 4 | -0.0333095 |
| RPL9 | ribosomal protein L9 | -0.0332922 |
| HMGB1 | high mobility group box 1 | -0.0332144 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0330945 |
| CCND1 | cyclin D1 | -0.0328693 |
| IER3 | immediate early response 3 | -0.0320169 |
| RNF217 | ring finger protein 217 | -0.031602 |
| RPS19 | ribosomal protein S19 | -0.0315243 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0311126 |
| S100A9 | S100 calcium binding protein A9 | -0.0308977 |
| RPS25 | ribosomal protein S25 | -0.030873 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0303457 |
| FRMD5 | FERM domain containing 5 | -0.0295884 |
| RPS12 | ribosomal protein S12 | -0.0286371 |
| RPS27A | ribosomal protein S27a | -0.0281635 |
| RPS21 | ribosomal protein S21 | -0.0280994 |
| RPL23 | ribosomal protein L23 | -0.0279451 |
| RPL12 | ribosomal protein L12 | -0.0278538 |
| EHBP1 | EH domain binding protein 1 | -0.0271077 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0270115 |
| RPL31 | ribosomal protein L31 | -0.0267593 |
| RPL26 | ribosomal protein L26 | -0.0267461 |
| RPL38 | ribosomal protein L38 | -0.0266485 |
| H1-0 | H1.0 linker histone | -0.0265999 |
| RPLP2 | ribosomal protein, large, P2 | -0.0263549 |
| TFF1 | trefoil factor 1 | -0.0261959 |
| LSAMP | limbic system-associated membrane protein | -0.025923 |
| RPL27 | ribosomal protein L27 | -0.0253441 |
| RAB10 | RAB10, member RAS oncogene family | -0.0247401 |
| KLK10 | kallikrein-related peptidase 10 | -0.0242543 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0240558 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0240269 |
| RPL37A | ribosomal protein L37a | -0.0235456 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0235115 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.023401 |
| SAMD5 | sterile alpha motif domain containing 5 | -0.0233722 |
| RAD51B | RAD51 paralog B | -0.0231322 |
| RPS23 | ribosomal protein S23 | -0.0230152 |
| RPS29 | ribosomal protein S29 | -0.0228463 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0226931 |
| CFTR | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) | -0.0221764 |
| RPL37 | ribosomal protein L37 | -0.0218283 |
| MECOM | MDS1 and EVI1 complex locus | -0.0216095 |
| RPL36 | ribosomal protein L36 | -0.0213603 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0211778 |
| ARHGAP6 | Rho GTPase activating protein 6 | -0.0208245 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0204339 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0204335 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0204024 |
| TFF3 | trefoil factor 3 (intestinal) | -0.0202705 |
| GNAS | GNAS complex locus | -0.0202335 |
| RPS17 | ribosomal protein S17 | -0.0200672 |
| FERMT1 | fermitin family member 1 | -0.0200664 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0194529 |
| RPL19 | ribosomal protein L19 | -0.0194026 |
| HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B | -0.0191722 |
| RPS16 | ribosomal protein S16 | -0.0191046 |
| TMEM117 | transmembrane protein 117 | -0.0190063 |
| RPL35 | ribosomal protein L35 | -0.0187948 |
| MTAP | methylthioadenosine phosphorylase | -0.0187917 |
| RPS10 | ribosomal protein S10 | -0.0187061 |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit | -0.0186489 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0186261 |
| RPL28 | ribosomal protein L28 | -0.0185771 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0185137 |
| TRAPPC9 | trafficking protein particle complex 9 | -0.0183097 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.018161 |
| NRXN3 | neurexin 3 | -0.0181223 |
| SH3D19 | SH3 domain containing 19 | -0.0180908 |
| RPS14 | ribosomal protein S14 | -0.0178193 |
| PHACTR2 | phosphatase and actin regulator 2 | -0.0177594 |
| RPL30 | ribosomal protein L30 | -0.0175357 |
