| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Allopurinol perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Allopurinol_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF2 | eukaryotic translation elongation factor 2 | 0.14434 |
| TMSB4X | thymosin beta 4, X-linked | 0.141537 |
| DST | dystonin | 0.117817 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.108159 |
| SPAG9 | sperm associated antigen 9 | 0.0866573 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0861406 |
| PGK1 | phosphoglycerate kinase 1 | 0.0860861 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.085622 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.073258 |
| MYOF | myoferlin | 0.072905 |
| APP | amyloid beta (A4) precursor protein | 0.0701904 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0668109 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0659095 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.061902 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0609608 |
| ANXA1 | annexin A1 | 0.0607437 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0607149 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0596064 |
| CANX | calnexin | 0.0550994 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0548872 |
| FMNL2 | formin-like 2 | 0.054752 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0542975 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0539746 |
| EZR | ezrin | 0.0536315 |
| HDAC9 | histone deacetylase 9 | 0.0529039 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0525014 |
| TXNRD1 | thioredoxin reductase 1 | 0.0524885 |
| RUNX1 | runt-related transcription factor 1 | 0.0519727 |
| LOXL2 | lysyl oxidase-like 2 | 0.0519108 |
| TNS3 | tensin 3 | 0.0505349 |
| JUN | jun proto-oncogene | 0.0500605 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0477405 |
| SQSTM1 | sequestosome 1 | 0.0468558 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0466139 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0465955 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0457294 |
| LDHA | lactate dehydrogenase A | 0.0452062 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0445078 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0440112 |
| YEATS2 | YEATS domain containing 2 | 0.042751 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0424677 |
| EFNA5 | ephrin-A5 | 0.0412222 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0401466 |
| PLK2 | polo-like kinase 2 | 0.0375931 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.036968 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0369644 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0363767 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0363013 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0362004 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0360339 |
| EPHA4 | EPH receptor A4 | 0.0353322 |
| FLNB | filamin B, beta | 0.0352057 |
| FNIP1 | folliculin interacting protein 1 | 0.0344416 |
| LRRC49 | leucine rich repeat containing 49 | 0.0344323 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0342609 |
| HDLBP | high density lipoprotein binding protein | 0.0339409 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0338876 |
| TP63 | tumor protein p63 | 0.0333844 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0332267 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0331744 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0321588 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0319062 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0315879 |
| CMIP | c-Maf inducing protein | 0.0314894 |
| TFRC | transferrin receptor | 0.0314049 |
| CSMD3 | CUB and Sushi multiple domains 3 | 0.0312847 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0311098 |
| ANXA2 | annexin A2 | 0.031056 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0303566 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0301221 |
| CALR | calreticulin | 0.0298838 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0294652 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0293411 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | 0.0291435 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0287601 |
| SLK | STE20-like kinase | 0.0284505 |
| DOCK11 | dedicator of cytokinesis 11 | 0.028346 |
| CAPRIN2 | caprin family member 2 | 0.0281858 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0281588 |
| PRELID2 | PRELI domain containing 2 | 0.02804 |
| NDRG1 | N-myc downstream regulated 1 | 0.0278364 |
| DENND1A | DENN/MADD domain containing 1A | 0.0277194 |
| ARRDC3 | arrestin domain containing 3 | 0.0275253 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0275207 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0271597 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0270381 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0269916 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.026899 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.0268177 |
| HELZ | helicase with zinc finger | 0.0265159 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0263538 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0260882 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0260481 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.025986 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0258575 |
| NAV2 | neuron navigator 2 | 0.0256524 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0256188 |
| CD44 | CD44 molecule (Indian blood group) | 0.0253589 |
| SET | SET nuclear proto-oncogene | 0.0252379 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0252291 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.331724 |
| VIM | vimentin | -0.200893 |
| MT2A | metallothionein 2A | -0.200326 |
| TMSB10 | thymosin beta 10 | -0.085075 |
| RPL35A | ribosomal protein L35a | -0.0720494 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0676336 |
| RPS6 | ribosomal protein S6 | -0.0670814 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0530141 |
| MT1E | metallothionein 1E | -0.0489313 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0425872 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0414409 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0409243 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0397677 |
| MT1X | metallothionein 1X | -0.0397249 |
| HMGA1 | high mobility group AT-hook 1 | -0.0378079 |
| RPL12 | ribosomal protein L12 | -0.0370274 |
| FTL | ferritin, light polypeptide | -0.0368793 |
| RPS8 | ribosomal protein S8 | -0.0366639 |
| ACTG1 | actin gamma 1 | -0.0366578 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0346788 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | -0.0339773 |
| RPLP0 | ribosomal protein, large, P0 | -0.033238 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.032791 |
| CENPF | centromere protein F, 350/400kDa | -0.0320285 |
| POTEF | POTE ankyrin domain family, member F | -0.0318536 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0317543 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0313048 |
| RIGI | RNA sensor RIG-I | -0.0306151 |
| TXNIP | thioredoxin interacting protein | -0.0302886 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0302235 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0300398 |
| RPL23 | ribosomal protein L23 | -0.0291648 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0291538 |
| PTMA | prothymosin, alpha | -0.0288523 |
| RPS23 | ribosomal protein S23 | -0.0287406 |
| RPL5 | ribosomal protein L5 | -0.0281784 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.026837 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0266841 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0258034 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0255886 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0255727 |
| RPS24 | ribosomal protein S24 | -0.0254509 |
| S100A9 | S100 calcium binding protein A9 | -0.025301 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.024644 |
| PFN1 | profilin 1 | -0.0244891 |
| RPLP2 | ribosomal protein, large, P2 | -0.0243419 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0241206 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.023693 |
| RPL28 | ribosomal protein L28 | -0.0228719 |
| RPLP1 | ribosomal protein, large, P1 | -0.0226341 |
| YBX1 | Y box binding protein 1 | -0.0223925 |
| RPL19 | ribosomal protein L19 | -0.0223233 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0222606 |
| RACK1 | receptor for activated C kinase 1 | -0.0218551 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0217748 |
| RPL36 | ribosomal protein L36 | -0.0212819 |
| RPL9 | ribosomal protein L9 | -0.0212568 |
| RPS19 | ribosomal protein S19 | -0.0212024 |
| FOSL1 | FOS-like antigen 1 | -0.0210738 |
| GART | phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase | -0.020908 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0208755 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0207512 |
| ATF7IP | activating transcription factor 7 interacting protein | -0.0197214 |
| RPS5 | ribosomal protein S5 | -0.0197023 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0193357 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0191754 |
| RPS14 | ribosomal protein S14 | -0.0191059 |
| RPL35 | ribosomal protein L35 | -0.0188702 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0187414 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0186061 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0185011 |
| S100A10 | S100 calcium binding protein A10 | -0.0183948 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0180595 |
| CCDC88A | coiled-coil domain containing 88A | -0.0180549 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0179452 |
| SRGN | serglycin | -0.0173517 |
| RPL36A | ribosomal protein L36a | -0.0170991 |
| SOCS6 | suppressor of cytokine signaling 6 | -0.0168544 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0163381 |
| FERMT1 | fermitin family member 1 | -0.0162512 |
| PMP22 | peripheral myelin protein 22 | -0.0160597 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0159886 |
| TPI1 | triosephosphate isomerase 1 | -0.0159572 |
| RPL34 | ribosomal protein L34 | -0.0159409 |
| GLO1 | glyoxalase I | -0.0159309 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0156363 |
| CENPE | centromere protein E, 312kDa | -0.015503 |
| RPS29 | ribosomal protein S29 | -0.0153845 |
| SEPTIN7 | septin 7 | -0.0152339 |
| DEK | DEK proto-oncogene | -0.0151929 |
| RPL27 | ribosomal protein L27 | -0.0151835 |
| S100A6 | S100 calcium binding protein A6 | -0.0150689 |
| TUBB6 | tubulin, beta 6 class V | -0.0150081 |
| DARS1 | aspartyl-tRNA synthetase 1 | -0.0150048 |
| CBX3 | chromobox homolog 3 | -0.0149424 |
| RPS15 | ribosomal protein S15 | -0.0148724 |
| TUBA1B | tubulin, alpha 1b | -0.0148111 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.0147788 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0147558 |
| PPIA | peptidylprolyl isomerase A (cyclophilin A) | -0.0147244 |
