| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Allopurinol perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Allopurinol_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PCBP2 | poly(rC) binding protein 2 | 0.179795 |
| USP34 | ubiquitin specific peptidase 34 | 0.14002 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.12674 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.121295 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.116053 |
| GRB10 | growth factor receptor-bound protein 10 | 0.109189 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.108998 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.102009 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.098698 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0972016 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0924275 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0923074 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0922256 |
| FAM13A | family with sequence similarity 13, member A | 0.0810069 |
| GOLGA4 | golgin A4 | 0.080743 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0764546 |
| RBM39 | RNA binding motif protein 39 | 0.0763116 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0727372 |
| NAV2 | neuron navigator 2 | 0.0695385 |
| ANXA1 | annexin A1 | 0.0679353 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0675473 |
| VEGFA | vascular endothelial growth factor A | 0.0652116 |
| ADM | adrenomedullin | 0.0638107 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0636222 |
| FN1 | fibronectin 1 | 0.0610689 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0604452 |
| RUNX1 | runt-related transcription factor 1 | 0.0598463 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0584488 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0583275 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0556895 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0533084 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0530624 |
| EFNA5 | ephrin-A5 | 0.0524745 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0512654 |
| LDHA | lactate dehydrogenase A | 0.0505493 |
| CALU | calumenin | 0.0502396 |
| APP | amyloid beta (A4) precursor protein | 0.0486249 |
| ATXN1 | ataxin 1 | 0.0472102 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0461305 |
| EIF3B | eukaryotic translation initiation factor 3, subunit B | 0.0454127 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0450318 |
| SMAD3 | SMAD family member 3 | 0.0450087 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0443788 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0443163 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0426813 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0425415 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0420413 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.041276 |
| ARF4 | ADP-ribosylation factor 4 | 0.0411823 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.041163 |
| EGFR | epidermal growth factor receptor | 0.0405659 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0405117 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0401873 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.040052 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0398961 |
| FAM107B | family with sequence similarity 107, member B | 0.0394604 |
| NBAS | neuroblastoma amplified sequence | 0.0388654 |
| ANXA2 | annexin A2 | 0.0385044 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.038402 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0382653 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0379058 |
| YEATS2 | YEATS domain containing 2 | 0.0378321 |
| TMSB4X | thymosin beta 4, X-linked | 0.0375636 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0372135 |
| SUCO | SUN domain containing ossification factor | 0.0366781 |
| PRELID2 | PRELI domain containing 2 | 0.0365132 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | 0.0363253 |
| SEC24A | SEC24 family member A | 0.0360551 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0358379 |
| FBXL13 | F-box and leucine-rich repeat protein 13 | 0.0357132 |
| SETD5 | SET domain containing 5 | 0.0356254 |
| MCL1 | myeloid cell leukemia 1 | 0.0354772 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0354385 |
| EZR | ezrin | 0.0352607 |
| ANXA5 | annexin A5 | 0.0352319 |
| COG5 | component of oligomeric golgi complex 5 | 0.0350811 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0349643 |
| FAM20C | family with sequence similarity 20, member C | 0.0349202 |
| TSPAN5 | tetraspanin 5 | 0.0343908 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0343466 |
| ZNF638 | zinc finger protein 638 | 0.0341906 |
| COPA | coatomer protein complex, subunit alpha | 0.0340885 |
| PTK2 | protein tyrosine kinase 2 | 0.0340066 |
| SRP54 | signal recognition particle 54kDa | 0.0339014 |
| RAB5A | RAB5A, member RAS oncogene family | 0.0337247 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0336941 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.033693 |
| ANO6 | anoctamin 6 | 0.03364 |
| KIF5B | kinesin family member 5B | 0.0334698 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0333497 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0332069 |
| CABIN1 | calcineurin binding protein 1 | 0.0331872 |
| HELZ | helicase with zinc finger | 0.0331418 |
| YME1L1 | YME1-like 1 ATPase | 0.0330945 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.032985 |
| FLNB | filamin B, beta | 0.0328098 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0327643 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0326858 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0326268 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0325408 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.228304 |
| TMSB10 | thymosin beta 10 | -0.144852 |
| FTL | ferritin, light polypeptide | -0.113123 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.112615 |
| RPLP1 | ribosomal protein, large, P1 | -0.0868227 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.085136 |
| GLCCI1 | glucocorticoid induced 1 | -0.0643848 |
| RPL35A | ribosomal protein L35a | -0.0527346 |
| NTN4 | netrin 4 | -0.0491686 |
| RPS19 | ribosomal protein S19 | -0.048254 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0481639 |
| NRP1 | neuropilin 1 | -0.0478753 |
| KYNU | kynureninase | -0.0467761 |
| RPS21 | ribosomal protein S21 | -0.0460894 |
| MT2A | metallothionein 2A | -0.0458461 |
| S100A6 | S100 calcium binding protein A6 | -0.0449745 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0437641 |
| RPS8 | ribosomal protein S8 | -0.0435318 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0433436 |
| PTMA | prothymosin, alpha | -0.0425601 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0420341 |
| HMGA2 | high mobility group AT-hook 2 | -0.0413868 |
| GNAS | GNAS complex locus | -0.0390029 |
| RPL34 | ribosomal protein L34 | -0.0381533 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0346512 |
| RPS24 | ribosomal protein S24 | -0.0343122 |
| NRG1 | neuregulin 1 | -0.0338572 |
| RPL23 | ribosomal protein L23 | -0.033265 |
| RPLP2 | ribosomal protein, large, P2 | -0.0325656 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0315687 |
| GPC6 | glypican 6 | -0.0313759 |
| RPS29 | ribosomal protein S29 | -0.0308796 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0304523 |
| RPS6 | ribosomal protein S6 | -0.02938 |
| S100A9 | S100 calcium binding protein A9 | -0.0290023 |
| IER3 | immediate early response 3 | -0.0284069 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0278832 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0269598 |
| S100A10 | S100 calcium binding protein A10 | -0.0269448 |
| RPL36 | ribosomal protein L36 | -0.0267633 |
| H1-0 | H1.0 linker histone | -0.0261081 |
| RPL28 | ribosomal protein L28 | -0.0259566 |
| VCL | vinculin | -0.0257899 |
| RPS25 | ribosomal protein S25 | -0.025709 |
| RPL19 | ribosomal protein L19 | -0.0255528 |
| RPL11 | ribosomal protein L11 | -0.0246656 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.0246149 |
| RPLP0 | ribosomal protein, large, P0 | -0.0242467 |
| RPS27 | ribosomal protein S27 | -0.0241005 |
| RPL37 | ribosomal protein L37 | -0.0237967 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0234054 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0231718 |
| RPS20 | ribosomal protein S20 | -0.0230632 |
| HMGA1 | high mobility group AT-hook 1 | -0.022458 |
| ARHGAP42 | Rho GTPase activating protein 42 | -0.0220982 |
| RAI14 | retinoic acid induced 14 | -0.0219848 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0219774 |
| ZNF804A | zinc finger protein 804A | -0.0217574 |
| RPL37A | ribosomal protein L37a | -0.0216499 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0216357 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0215953 |
| RPL38 | ribosomal protein L38 | -0.0210348 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0208984 |
| RPS17 | ribosomal protein S17 | -0.0208536 |
| ENOSF1 | enolase superfamily member 1 | -0.0208261 |
| RPS13 | ribosomal protein S13 | -0.0204541 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.020192 |
| HEG1 | heart development protein with EGF-like domains 1 | -0.0201366 |
| LAMA4 | laminin, alpha 4 | -0.0201046 |
| ZNF385D | zinc finger protein 385D | -0.0200246 |
| AHNAK | AHNAK nucleoprotein | -0.0197754 |
| SYT1 | synaptotagmin I | -0.0196744 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0194299 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0194217 |
| RPS5 | ribosomal protein S5 | -0.0194015 |
| HLA-B | major histocompatibility complex, class I, B | -0.0189542 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 | -0.0188954 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0187426 |
| RPS14 | ribosomal protein S14 | -0.0186994 |
| RPL27A | ribosomal protein L27a | -0.0186887 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0186793 |
| RPL12 | ribosomal protein L12 | -0.0186751 |
| RPS15 | ribosomal protein S15 | -0.0185199 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0184227 |
| RPL9 | ribosomal protein L9 | -0.0184037 |
| RPL32 | ribosomal protein L32 | -0.0180513 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0179389 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0178746 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -0.0177775 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0174914 |
| OSMR | oncostatin M receptor | -0.0173931 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0172937 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0172196 |
| SEC61G | Sec61 gamma subunit | -0.0171988 |
| RPS16 | ribosomal protein S16 | -0.0170881 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0170372 |
| AOPEP | aminopeptidase O (putative) | -0.0169156 |
| RPL5 | ribosomal protein L5 | -0.0166412 |
| RPS23 | ribosomal protein S23 | -0.0166043 |
| RPS12 | ribosomal protein S12 | -0.0163222 |
