| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Allopurinol perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Allopurinol_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.071904 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0699349 |
| ANXA2 | annexin A2 | 0.0672052 |
| NDRG1 | N-myc downstream regulated 1 | 0.0626761 |
| KRT17 | keratin 17, type I | 0.0606122 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0566938 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0561289 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0557361 |
| KYNU | kynureninase | 0.0546034 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.05415 |
| SPAG9 | sperm associated antigen 9 | 0.052258 |
| RBM39 | RNA binding motif protein 39 | 0.0485934 |
| FAM13A | family with sequence similarity 13, member A | 0.0475225 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0456972 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0453902 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0442962 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0441302 |
| PCBP2 | poly(rC) binding protein 2 | 0.0429638 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0421035 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0407801 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0403276 |
| ASPH | aspartate beta-hydroxylase | 0.0395975 |
| PDE10A | phosphodiesterase 10A | 0.039262 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0392144 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0383274 |
| VEGFA | vascular endothelial growth factor A | 0.0383272 |
| ATP11A | ATPase, class VI, type 11A | 0.0378827 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0367346 |
| GLG1 | golgi glycoprotein 1 | 0.036473 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0360043 |
| LAMB3 | laminin, beta 3 | 0.0357698 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0357564 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0355553 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0354905 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0346464 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0331871 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0330265 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0321875 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0315089 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0313779 |
| RTN4 | reticulon 4 | 0.0312923 |
| DST | dystonin | 0.031279 |
| TMSB4X | thymosin beta 4, X-linked | 0.0308792 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0306798 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0303594 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0302784 |
| OGA | O-GlcNAcase | 0.0295171 |
| TOP1 | topoisomerase (DNA) I | 0.0294459 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0290624 |
| VCL | vinculin | 0.0285505 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0282658 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0281013 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0280584 |
| LDHA | lactate dehydrogenase A | 0.0276998 |
| PTEN | phosphatase and tensin homolog | 0.0274843 |
| EGFR | epidermal growth factor receptor | 0.0270366 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | 0.0269637 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0269194 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0268786 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0268751 |
| MYOF | myoferlin | 0.0263969 |
| APP | amyloid beta (A4) precursor protein | 0.0263685 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0261411 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0258975 |
| ANO6 | anoctamin 6 | 0.0257791 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0256791 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0254878 |
| HM13 | histocompatibility (minor) 13 | 0.0252973 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.02519 |
| SQSTM1 | sequestosome 1 | 0.0250751 |
| PGK1 | phosphoglycerate kinase 1 | 0.0247674 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0245573 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0243888 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0237267 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0232654 |
| SHTN1 | shootin 1 | 0.0230774 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.022994 |
| HELZ | helicase with zinc finger | 0.022932 |
| PHF21A | PHD finger protein 21A | 0.022881 |
| CANX | calnexin | 0.0228061 |
| SMAD3 | SMAD family member 3 | 0.0227822 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0227101 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0226617 |
| YTHDC1 | YTH domain containing 1 | 0.0225749 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0217187 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0216617 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0214848 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.021249 |
| RNF149 | ring finger protein 149 | 0.0212079 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0210386 |
| IST1 | increased sodium tolerance 1 homolog (yeast) | 0.0206568 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0206191 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0206148 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0205376 |
| ENO1 | enolase 1, (alpha) | 0.0204878 |
| PHF3 | PHD finger protein 3 | 0.0204792 |
| TXNRD1 | thioredoxin reductase 1 | 0.0204468 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0203768 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0203004 |
| MATR3 | matrin 3 | 0.0202867 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.0956654 |
| LAMC2 | laminin, gamma 2 | -0.0830674 |
| ATOSA | atos homolog A | -0.0740458 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.071054 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0628532 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.0611066 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0602835 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0602575 |
| STC1 | stanniocalcin 1 | -0.0565571 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0529592 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0512082 |
| HLA-B | major histocompatibility complex, class I, B | -0.0508082 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0499087 |
| POTEF | POTE ankyrin domain family, member F | -0.0433166 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0430167 |
| VIM | vimentin | -0.0400661 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0398105 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0397108 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0384898 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.038351 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0380478 |
| RPL19 | ribosomal protein L19 | -0.0363103 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.0347552 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0343878 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0342433 |
| TMSB10 | thymosin beta 10 | -0.033403 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0333688 |
| CD44 | CD44 molecule (Indian blood group) | -0.0332085 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.033134 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0329366 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0329028 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0326777 |
| ARHGEF4 | Rho guanine nucleotide exchange factor (GEF) 4 | -0.0324509 |
| RREB1 | ras responsive element binding protein 1 | -0.0319429 |
| RAI14 | retinoic acid induced 14 | -0.0319124 |
| SSH2 | slingshot protein phosphatase 2 | -0.0312667 |
| MYO1D | myosin ID | -0.0309465 |
| RPS19 | ribosomal protein S19 | -0.0307749 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0306671 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0301567 |
| S100A9 | S100 calcium binding protein A9 | -0.029939 |
| TMPRSS4 | transmembrane protease, serine 4 | -0.0298727 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.0297478 |
| S100A10 | S100 calcium binding protein A10 | -0.029556 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0293741 |
| CLMP | CXADR-like membrane protein | -0.0293154 |
| YAP1 | Yes-associated protein 1 | -0.0292421 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | -0.0290155 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0285906 |
| USP53 | ubiquitin specific peptidase 53 | -0.0282954 |
| RNF24 | ring finger protein 24 | -0.0282449 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0278613 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0275398 |
| CCNI | cyclin I | -0.0274775 |
| CLDN4 | claudin 4 | -0.0270183 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0268553 |
| SPIRE1 | spire-type actin nucleation factor 1 | -0.0265216 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0264877 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | -0.0262898 |
| PITPNM2 | phosphatidylinositol transfer protein, membrane-associated 2 | -0.0262608 |
| ACTN1 | actinin, alpha 1 | -0.0262165 |
| BTBD10 | BTB (POZ) domain containing 10 | -0.0261111 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0261076 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | -0.0259814 |
| FOXO3 | forkhead box O3 | -0.0258842 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0254037 |
| MT2A | metallothionein 2A | -0.0253389 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | -0.0252857 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0252578 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0252379 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0252009 |
| MXD1 | MAX dimerization protein 1 | -0.0251539 |
| PPP2R2C | protein phosphatase 2, regulatory subunit B, gamma | -0.0245813 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | -0.024482 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0244815 |
| RFX7 | regulatory factor X, 7 | -0.0243083 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0243076 |
| KLF6 | Kruppel-like factor 6 | -0.0243065 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | -0.024286 |
| ATP11B | ATPase, class VI, type 11B | -0.0241905 |
| SDC4 | syndecan 4 | -0.0238297 |
| RAB5A | RAB5A, member RAS oncogene family | -0.0238082 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0236243 |
| BCL2L1 | BCL2-like 1 | -0.0233427 |
| SCAPER | S-phase cyclin A-associated protein in the ER | -0.0233326 |
| CLIC4 | chloride intracellular channel 4 | -0.0232803 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0231632 |
| IGF2 | insulin-like growth factor 2 | -0.0231107 |
| TMOD3 | tropomodulin 3 (ubiquitous) | -0.0228567 |
| WASF2 | WAS protein family, member 2 | -0.0226972 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0224252 |
| CSTB | cystatin B (stefin B) | -0.022368 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0223405 |
| ENKUR | enkurin, TRPC channel interacting protein | -0.0222796 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0222759 |
| PRDM1 | PR domain containing 1, with ZNF domain | -0.0222513 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0222505 |
| SEPTIN2 | septin 2 | -0.0220192 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0216805 |
| RPL31 | ribosomal protein L31 | -0.0215684 |
