| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Allopurinol perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Allopurinol_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.21746 |
| EFNA5 | ephrin-A5 | 0.159707 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.158299 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.105072 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.104032 |
| MYOF | myoferlin | 0.0826709 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0788479 |
| MCL1 | myeloid cell leukemia 1 | 0.0787222 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0768335 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0754819 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0718325 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0707502 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0667569 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0621976 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0612736 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0600256 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0594257 |
| EZR | ezrin | 0.0585438 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0549049 |
| GDA | guanine deaminase | 0.0542991 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0537529 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0487125 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.046275 |
| CD109 | CD109 molecule | 0.0461461 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0451875 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0449079 |
| FNIP1 | folliculin interacting protein 1 | 0.0444724 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0441079 |
| CANX | calnexin | 0.043749 |
| PGK1 | phosphoglycerate kinase 1 | 0.0435914 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0435742 |
| USP34 | ubiquitin specific peptidase 34 | 0.0434058 |
| DNER | delta/notch-like EGF repeat containing | 0.0422194 |
| CDH13 | cadherin 13 | 0.0418875 |
| ANXA1 | annexin A1 | 0.0410191 |
| CD44 | CD44 molecule (Indian blood group) | 0.0402846 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0392401 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0380099 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.0371694 |
| STC2 | stanniocalcin 2 | 0.0369041 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0364233 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0359854 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0358829 |
| PCBP2 | poly(rC) binding protein 2 | 0.0353241 |
| HDAC4 | histone deacetylase 4 | 0.0345467 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0345178 |
| LDHA | lactate dehydrogenase A | 0.0337932 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0335589 |
| INHBA | inhibin, beta A | 0.0328365 |
| DST | dystonin | 0.0327517 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0325986 |
| FLNB | filamin B, beta | 0.0323913 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0323686 |
| FLNA | filamin A, alpha | 0.0322516 |
| ANXA2 | annexin A2 | 0.0321726 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.031931 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0315247 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0312221 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0304162 |
| STC1 | stanniocalcin 1 | 0.0299493 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0298771 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0296118 |
| PRELID2 | PRELI domain containing 2 | 0.0295587 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0295283 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.0286831 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0286682 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0286479 |
| TMX4 | thioredoxin-related transmembrane protein 4 | 0.0280123 |
| DENND1A | DENN/MADD domain containing 1A | 0.0278291 |
| NBEAL1 | neurobeachin-like 1 | 0.0275382 |
| ABLIM1 | actin binding LIM protein 1 | 0.0273367 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | 0.0271739 |
| JMJD1C | jumonji domain containing 1C | 0.0271189 |
| ADGRD1 | adhesion G protein-coupled receptor D1 | 0.0269632 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0268755 |
| HDLBP | high density lipoprotein binding protein | 0.0266302 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0263391 |
| COPA | coatomer protein complex, subunit alpha | 0.0261829 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0258443 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0257252 |
| ATXN1 | ataxin 1 | 0.0255657 |
| PYGL | phosphorylase, glycogen, liver | 0.0254926 |
| PCBP3 | poly(rC) binding protein 3 | 0.0253902 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0251652 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0247927 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.0243671 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0242458 |
| BSG | basigin (Ok blood group) | 0.024067 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0240051 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0239985 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0238235 |
| PDE10A | phosphodiesterase 10A | 0.0234849 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0228059 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0224824 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0220835 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0220464 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0219392 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0218791 |
| PTEN | phosphatase and tensin homolog | 0.0218355 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.0216887 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.171752 |
| FTL | ferritin, light polypeptide | -0.0813234 |
| TMSB10 | thymosin beta 10 | -0.0777912 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0744076 |
| RPLP1 | ribosomal protein, large, P1 | -0.0686814 |
| RPS6 | ribosomal protein S6 | -0.0580084 |
| PTMA | prothymosin, alpha | -0.0530422 |
| RPL37A | ribosomal protein L37a | -0.0485867 |
| RPS8 | ribosomal protein S8 | -0.0477979 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0477829 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0476064 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0428883 |
| RPS24 | ribosomal protein S24 | -0.0413801 |
| RPS19 | ribosomal protein S19 | -0.0412139 |
| RPL12 | ribosomal protein L12 | -0.0392046 |
| RPL23 | ribosomal protein L23 | -0.0383614 |
| RPL19 | ribosomal protein L19 | -0.0375346 |
| GRAMD1B | GRAM domain containing 1B | -0.0365563 |
| RPL26 | ribosomal protein L26 | -0.0365383 |
| RPS12 | ribosomal protein S12 | -0.0363389 |
| RPS23 | ribosomal protein S23 | -0.0351104 |
| RPS2 | ribosomal protein S2 | -0.0340066 |
| RPLP2 | ribosomal protein, large, P2 | -0.0333432 |
| MT2A | metallothionein 2A | -0.0332418 |
| CENPF | centromere protein F, 350/400kDa | -0.0323082 |
| RPS16 | ribosomal protein S16 | -0.0311528 |
| RPS29 | ribosomal protein S29 | -0.0305154 |
| RGS2 | regulator of G-protein signaling 2 | -0.0299067 |
| GNAS | GNAS complex locus | -0.0298415 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.029714 |
| NEK7 | NIMA-related kinase 7 | -0.0296729 |
| RPS21 | ribosomal protein S21 | -0.0294274 |
| RPL35A | ribosomal protein L35a | -0.0289551 |
| RPL11 | ribosomal protein L11 | -0.0283051 |
| RPL36 | ribosomal protein L36 | -0.028129 |
| RPL34 | ribosomal protein L34 | -0.0279926 |
| RPS25 | ribosomal protein S25 | -0.0278529 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0277057 |
| RPL31 | ribosomal protein L31 | -0.0273664 |
| RPS14 | ribosomal protein S14 | -0.0273445 |
| S100A6 | S100 calcium binding protein A6 | -0.0268349 |
| RPL37 | ribosomal protein L37 | -0.0261024 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0259884 |
| RNF145 | ring finger protein 145 | -0.025853 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0257777 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0257619 |
| RPL38 | ribosomal protein L38 | -0.0254757 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.02483 |
| RPL35 | ribosomal protein L35 | -0.0246408 |
| RPLP0 | ribosomal protein, large, P0 | -0.0245613 |
| RPS27 | ribosomal protein S27 | -0.0235995 |
| USP3 | ubiquitin specific peptidase 3 | -0.0235869 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0235355 |
| RPS17 | ribosomal protein S17 | -0.023167 |
| RPS3 | ribosomal protein S3 | -0.0230583 |
| RPL5 | ribosomal protein L5 | -0.0229962 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0229791 |
| RPL27 | ribosomal protein L27 | -0.0226893 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0224358 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | -0.0222054 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0220733 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0217806 |
| RPS27A | ribosomal protein S27a | -0.02174 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0215928 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0214441 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0214194 |
| RPL39 | ribosomal protein L39 | -0.0214107 |
| RPS13 | ribosomal protein S13 | -0.0213336 |
| RPL9 | ribosomal protein L9 | -0.0211176 |
| B2M | beta-2-microglobulin | -0.0207617 |
| RPS20 | ribosomal protein S20 | -0.0204289 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0195242 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.019409 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0193646 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0193526 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0193414 |
| SRGN | serglycin | -0.0192595 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0190992 |
| RPL28 | ribosomal protein L28 | -0.0190941 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0190915 |
| RPL32 | ribosomal protein L32 | -0.0189556 |
| RPS4X | ribosomal protein S4, X-linked | -0.0184549 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0183916 |
| RPL36A | ribosomal protein L36a | -0.0180262 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0179669 |
| RPL7A | ribosomal protein L7a | -0.0179408 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0176962 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.017512 |
| RPS10 | ribosomal protein S10 | -0.0174508 |
| QKI | QKI, KH domain containing, RNA binding | -0.0174492 |
| SLF1 | SMC5-SMC6 complex localization factor 1 | -0.0172907 |
| RACK1 | receptor for activated C kinase 1 | -0.0172715 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0171438 |
| NUP58 | nucleoporin 58 | -0.0167108 |
| ACTG1 | actin gamma 1 | -0.0166402 |
| ZNF292 | zinc finger protein 292 | -0.0165883 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0164644 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0164631 |
| GREM2 | gremlin 2, DAN family BMP antagonist | -0.0163231 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0160854 |
