| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Allopurinol perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Allopurinol_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB4X | thymosin beta 4, X-linked | 0.134476 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.127559 |
| EZR | ezrin | 0.0856389 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0809705 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0750202 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0661574 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0638604 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0617648 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0596589 |
| GOLGA4 | golgin A4 | 0.0570876 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0545649 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0509388 |
| LDHA | lactate dehydrogenase A | 0.0507354 |
| RTN4 | reticulon 4 | 0.049277 |
| FLNB | filamin B, beta | 0.0488683 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0477703 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0475544 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0454251 |
| USP34 | ubiquitin specific peptidase 34 | 0.0433607 |
| PCBP2 | poly(rC) binding protein 2 | 0.0427506 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0427312 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | 0.0425967 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0424726 |
| EGFR | epidermal growth factor receptor | 0.0413758 |
| NBAS | neuroblastoma amplified sequence | 0.0413637 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0411212 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.040798 |
| TJP1 | tight junction protein 1 | 0.0383358 |
| TXNIP | thioredoxin interacting protein | 0.0379654 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0377232 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0376059 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0372497 |
| HDAC9 | histone deacetylase 9 | 0.0364493 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0359972 |
| SMC3 | structural maintenance of chromosomes 3 | 0.0358019 |
| AHI1 | Abelson helper integration site 1 | 0.0352069 |
| SQSTM1 | sequestosome 1 | 0.0350927 |
| SBF2 | SET binding factor 2 | 0.0349037 |
| EFNA5 | ephrin-A5 | 0.0339254 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0333879 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0329427 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0329359 |
| RHBDD1 | rhomboid domain containing 1 | 0.0328938 |
| DUSP4 | dual specificity phosphatase 4 | 0.032887 |
| ASPH | aspartate beta-hydroxylase | 0.0327199 |
| YAP1 | Yes-associated protein 1 | 0.0325883 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0324437 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0320353 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0320085 |
| JMJD1C | jumonji domain containing 1C | 0.0316376 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0312318 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0310561 |
| GOLGB1 | golgin B1 | 0.0310143 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0309569 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0307644 |
| ARRDC3 | arrestin domain containing 3 | 0.030675 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.030596 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0304768 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0304736 |
| PDGFC | platelet derived growth factor C | 0.0303733 |
| RBM25 | RNA binding motif protein 25 | 0.0302258 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0300558 |
| TBK1 | TANK-binding kinase 1 | 0.0297136 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0296774 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0296384 |
| COG6 | component of oligomeric golgi complex 6 | 0.0294372 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0292997 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0289996 |
| ARF4 | ADP-ribosylation factor 4 | 0.0288008 |
| ATXN2 | ataxin 2 | 0.0286234 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0284407 |
| YEATS2 | YEATS domain containing 2 | 0.0282624 |
| ATRN | attractin | 0.0282444 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0282323 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0279491 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0279359 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0278552 |
| PKM | pyruvate kinase, muscle | 0.0278154 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0277051 |
| TBC1D15 | TBC1 domain family, member 15 | 0.0274554 |
| COG5 | component of oligomeric golgi complex 5 | 0.0272792 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0271279 |
| ZNF292 | zinc finger protein 292 | 0.0270368 |
| TBC1D32 | TBC1 domain family, member 32 | 0.0269606 |
| KMT5B | lysine methyltransferase 5B | 0.026735 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0261787 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) | 0.0261223 |
| EPB41 | erythrocyte membrane protein band 4.1 | 0.025996 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0259935 |
| ATM | ATM serine/threonine kinase | 0.0259718 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0258285 |
| CEP350 | centrosomal protein 350kDa | 0.0257419 |
| MYOF | myoferlin | 0.025669 |
| AMOTL2 | angiomotin like 2 | 0.0255219 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0253816 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0253094 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0252521 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0250659 |
| PMM2 | phosphomannomutase 2 | 0.0250387 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0249851 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AHNAK | AHNAK nucleoprotein | -0.137838 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.130593 |
| BMP10 | bone morphogenetic protein 10 | -0.121456 |
| VCL | vinculin | -0.0973229 |
| FOXP1 | forkhead box P1 | -0.09568 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0872237 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0857598 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0853635 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0813392 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0802014 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0741761 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0634149 |
| GLI3 | GLI family zinc finger 3 | -0.0634067 |
| MKI67 | marker of proliferation Ki-67 | -0.0600425 |
| RPLP1 | ribosomal protein, large, P1 | -0.0599847 |
| NAV2 | neuron navigator 2 | -0.0515406 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0477645 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0469574 |
| RPL26 | ribosomal protein L26 | -0.045217 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0449145 |
| RPS6 | ribosomal protein S6 | -0.043567 |
| RPL34 | ribosomal protein L34 | -0.0424153 |
| RPL19 | ribosomal protein L19 | -0.0411192 |
| PPM1L | protein phosphatase, Mg2+/Mn2+ dependent, 1L | -0.0407482 |
| RPS21 | ribosomal protein S21 | -0.040738 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0404278 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0403585 |
| CCND1 | cyclin D1 | -0.0394196 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | -0.0389595 |
| PTMA | prothymosin, alpha | -0.0375682 |
| ZNF438 | zinc finger protein 438 | -0.0366645 |
| RPS8 | ribosomal protein S8 | -0.0363728 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0360382 |
| GNAS | GNAS complex locus | -0.0354809 |
| RPL35A | ribosomal protein L35a | -0.0353196 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0347903 |
| PDE7B | phosphodiesterase 7B | -0.0346131 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0337941 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0333663 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0329846 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0318814 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0315277 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0311477 |
| RPS25 | ribosomal protein S25 | -0.0310738 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0308075 |
| EBNA1BP2 | EBNA1 binding protein 2 | -0.0295543 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0294227 |
| UNC13A | unc-13 homolog A (C. elegans) | -0.0288289 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0287912 |
| CALR | calreticulin | -0.028439 |
| RPS27A | ribosomal protein S27a | -0.0284345 |
| CRPPA | CDP-L-ribitol pyrophosphorylase A | -0.0281545 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0278343 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.0277569 |
| RPL27A | ribosomal protein L27a | -0.0276609 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0272992 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | -0.0272384 |
| RPS14 | ribosomal protein S14 | -0.0270088 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0266294 |
| S100A4 | S100 calcium binding protein A4 | -0.0266014 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0262817 |
| RPS20 | ribosomal protein S20 | -0.025856 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0255981 |
| RPL36 | ribosomal protein L36 | -0.0253191 |
| RPL35 | ribosomal protein L35 | -0.0252112 |
| TPI1 | triosephosphate isomerase 1 | -0.0251061 |
| RPL38 | ribosomal protein L38 | -0.0250911 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0249574 |
| NMD3 | NMD3 ribosome export adaptor | -0.0248074 |
| RPL23 | ribosomal protein L23 | -0.024498 |
| RPS16 | ribosomal protein S16 | -0.024177 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0239259 |
| HMGB1 | high mobility group box 1 | -0.0238444 |
| CEP112 | centrosomal protein 112kDa | -0.0237971 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0237849 |
| ACTG1 | actin gamma 1 | -0.0237417 |
| RPS19 | ribosomal protein S19 | -0.0236879 |
| RPS23 | ribosomal protein S23 | -0.023684 |
| ITGA10 | integrin, alpha 10 | -0.02352 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0233284 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0233214 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0232366 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.022957 |
| MYO5C | myosin VC | -0.0228445 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0225677 |
| RPL28 | ribosomal protein L28 | -0.0222814 |
| S100A10 | S100 calcium binding protein A10 | -0.0220408 |
| HIBCH | 3-hydroxyisobutyryl-CoA hydrolase | -0.0220142 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0219625 |
| RPS3 | ribosomal protein S3 | -0.0219175 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0218677 |
| CDC73 | cell division cycle 73 | -0.0217917 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0217816 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.0217758 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.021769 |
| DIAPH3 | diaphanous-related formin 3 | -0.0217479 |
| EXOC4 | exocyst complex component 4 | -0.0215675 |
| TMSB10 | thymosin beta 10 | -0.0214016 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0213985 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | -0.0210217 |
