| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Allopurinol perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Allopurinol_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.185794 |
| FN1 | fibronectin 1 | 0.165759 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.160825 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.160489 |
| ADM | adrenomedullin | 0.0867896 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0702906 |
| SPAG9 | sperm associated antigen 9 | 0.0670712 |
| NAV2 | neuron navigator 2 | 0.0650734 |
| VEGFA | vascular endothelial growth factor A | 0.0645511 |
| FLNA | filamin A, alpha | 0.0638671 |
| TMSB4X | thymosin beta 4, X-linked | 0.0616035 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.061449 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0596159 |
| SFTPA2 | surfactant protein A2 | 0.0576608 |
| ANXA2 | annexin A2 | 0.0575866 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0557492 |
| ARRDC3 | arrestin domain containing 3 | 0.0539325 |
| PCBP2 | poly(rC) binding protein 2 | 0.0537797 |
| APP | amyloid beta (A4) precursor protein | 0.0518854 |
| GOLGA4 | golgin A4 | 0.0512914 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0504557 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0497479 |
| OGA | O-GlcNAcase | 0.0492314 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0475607 |
| ANLN | anillin, actin binding protein | 0.0461905 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0436918 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0422238 |
| MATR3 | matrin 3 | 0.0407949 |
| MSN | moesin | 0.0394898 |
| WDFY1 | WD repeat and FYVE domain containing 1 | 0.0393803 |
| DIAPH3 | diaphanous-related formin 3 | 0.0391369 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0380053 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.036458 |
| CDK19 | cyclin-dependent kinase 19 | 0.036357 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0363349 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0362974 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0362097 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0362034 |
| PHIP | pleckstrin homology domain interacting protein | 0.0361034 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0355495 |
| TPM3 | tropomyosin 3 | 0.0351188 |
| FNIP1 | folliculin interacting protein 1 | 0.0337801 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0335225 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0323396 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0323116 |
| CENPF | centromere protein F, 350/400kDa | 0.0322553 |
| POTEF | POTE ankyrin domain family, member F | 0.0321592 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0320582 |
| EZR | ezrin | 0.0308954 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 0.0307315 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0303905 |
| RBM39 | RNA binding motif protein 39 | 0.0300284 |
| IPO7 | importin 7 | 0.0300097 |
| MKI67 | marker of proliferation Ki-67 | 0.0297102 |
| ANXA1 | annexin A1 | 0.0296927 |
| HDLBP | high density lipoprotein binding protein | 0.0291086 |
| NDRG1 | N-myc downstream regulated 1 | 0.0290759 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0290456 |
| KIF4A | kinesin family member 4A | 0.0290368 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0287567 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0284291 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0283862 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0279911 |
| RND3 | Rho family GTPase 3 | 0.0278355 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0276216 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0275264 |
| SERINC1 | serine incorporator 1 | 0.0269126 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0265893 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.026527 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0259681 |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.0258864 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0256311 |
| KIF5B | kinesin family member 5B | 0.0255362 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0254768 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0254326 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0254204 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0253196 |
| CREBRF | CREB3 regulatory factor | 0.0251441 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0251211 |
| SMC4 | structural maintenance of chromosomes 4 | 0.02501 |
| SLC25A26 | solute carrier family 25 (S-adenosylmethionine carrier), member 26 | 0.024533 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0244422 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0242892 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0239701 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0237895 |
| GAS2L3 | growth arrest-specific 2 like 3 | 0.0237829 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0231148 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0231057 |
| NONO | non-POU domain containing, octamer-binding | 0.0229996 |
| ERBIN | erbb2 interacting protein | 0.0226346 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0224221 |
| CLTC | clathrin, heavy chain (Hc) | 0.022366 |
| TAOK1 | TAO kinase 1 | 0.0223496 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0221299 |
| NF1 | neurofibromin 1 | 0.0217758 |
| PTMA | prothymosin, alpha | 0.0217618 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.021606 |
| PGK1 | phosphoglycerate kinase 1 | 0.0215841 |
| CRY1 | cryptochrome circadian clock 1 | 0.0214317 |
| ATP13A3 | ATPase type 13A3 | 0.0213983 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.183014 |
| FRMD4A | FERM domain containing 4A | -0.161026 |
| VCL | vinculin | -0.111203 |
| IER3 | immediate early response 3 | -0.107744 |
| VIM | vimentin | -0.105463 |
| GLIS3 | GLIS family zinc finger 3 | -0.105432 |
| HLA-B | major histocompatibility complex, class I, B | -0.103941 |
| FTL | ferritin, light polypeptide | -0.0983982 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0942813 |
| TMSB10 | thymosin beta 10 | -0.0889181 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0782166 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0688096 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0681366 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.066255 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0626484 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0587319 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.057207 |
| HLA-A | major histocompatibility complex, class I, A | -0.0566654 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0562729 |
| B2M | beta-2-microglobulin | -0.0519284 |
| BICC1 | BicC family RNA binding protein 1 | -0.0499027 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.048683 |
| EGFR | epidermal growth factor receptor | -0.0477548 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0476442 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0460062 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0457589 |
| RPS8 | ribosomal protein S8 | -0.0456387 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0448798 |
| HMGA2 | high mobility group AT-hook 2 | -0.0433516 |
| MT2A | metallothionein 2A | -0.0432705 |
| DST | dystonin | -0.0423027 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0421169 |
| RIGI | RNA sensor RIG-I | -0.0416954 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0403269 |
| ENO1 | enolase 1, (alpha) | -0.0392773 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0376454 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | -0.0376232 |
| RAI14 | retinoic acid induced 14 | -0.0374184 |
| TENM2 | teneurin transmembrane protein 2 | -0.0373306 |
| ASPH | aspartate beta-hydroxylase | -0.0373159 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0372971 |
| EGR1 | early growth response 1 | -0.037117 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0367541 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.036566 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0362221 |
| RPS12 | ribosomal protein S12 | -0.0356446 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0355252 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0354813 |
| RPS19 | ribosomal protein S19 | -0.0348223 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0332298 |
| PRR16 | proline rich 16 | -0.0330872 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.033041 |
| PALLD | palladin, cytoskeletal associated protein | -0.0328667 |
| RPS6 | ribosomal protein S6 | -0.0328581 |
| KYNU | kynureninase | -0.0328539 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0327647 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0323986 |
| RPS14 | ribosomal protein S14 | -0.0322051 |
| NAV1 | neuron navigator 1 | -0.0322029 |
| RPLP1 | ribosomal protein, large, P1 | -0.0321252 |
| TNS3 | tensin 3 | -0.0320062 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0318789 |
| VCAN | versican | -0.0317305 |
| RPL35A | ribosomal protein L35a | -0.0315485 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0313584 |
| WTAP | Wilms tumor 1 associated protein | -0.030437 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0302631 |
| DIAPH2 | diaphanous-related formin 2 | -0.0297685 |
| CLIC4 | chloride intracellular channel 4 | -0.029533 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0288841 |
| FAM20C | family with sequence similarity 20, member C | -0.0288384 |
| RPS24 | ribosomal protein S24 | -0.0288095 |
| RPLP2 | ribosomal protein, large, P2 | -0.0286927 |
| RPL26 | ribosomal protein L26 | -0.0286424 |
| RAD51B | RAD51 paralog B | -0.0284909 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0284031 |
| NABP1 | nucleic acid binding protein 1 | -0.0281759 |
| LRRC7 | leucine rich repeat containing 7 | -0.0278324 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0277446 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0276351 |
| C3 | complement component 3 | -0.0276155 |
| RNF213 | ring finger protein 213 | -0.0275535 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0274774 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0272561 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0271903 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0269215 |
| QKI | QKI, KH domain containing, RNA binding | -0.02641 |
| RPL28 | ribosomal protein L28 | -0.02634 |
| INTS6 | integrator complex subunit 6 | -0.0261682 |
| LOXL2 | lysyl oxidase-like 2 | -0.0260251 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0257151 |
| HDAC9 | histone deacetylase 9 | -0.0256489 |
| RPL12 | ribosomal protein L12 | -0.0252064 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0251162 |
| CADM1 | cell adhesion molecule 1 | -0.0249779 |
| PLIN2 | perilipin 2 | -0.0249669 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0248277 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0246767 |
| RPS23 | ribosomal protein S23 | -0.0241217 |
| BNC2 | basonuclin 2 | -0.0240188 |
