| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Allopurinol perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Allopurinol_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TRIO | trio Rho guanine nucleotide exchange factor | 0.116094 |
| PRRC2C | proline-rich coiled-coil 2C | 0.115438 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.102885 |
| CD109 | CD109 molecule | 0.0893931 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0869704 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0851083 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0812296 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0601432 |
| SUCO | SUN domain containing ossification factor | 0.0579297 |
| VEGFA | vascular endothelial growth factor A | 0.0568757 |
| GOLGA4 | golgin A4 | 0.0561629 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0556822 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0554057 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0548298 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0541016 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0531626 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0521052 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0520983 |
| NDRG1 | N-myc downstream regulated 1 | 0.0520658 |
| PCBP2 | poly(rC) binding protein 2 | 0.0520634 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0518775 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0511113 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0510609 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0502566 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0496665 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0489401 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0480151 |
| TPR | translocated promoter region, nuclear basket protein | 0.0471024 |
| TMSB4X | thymosin beta 4, X-linked | 0.0461584 |
| FAM13A | family with sequence similarity 13, member A | 0.0460768 |
| HELZ | helicase with zinc finger | 0.0449961 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0446851 |
| STC2 | stanniocalcin 2 | 0.0443686 |
| LMNA | lamin A/C | 0.0425256 |
| CADM1 | cell adhesion molecule 1 | 0.0415962 |
| CENPF | centromere protein F, 350/400kDa | 0.0415646 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0406738 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0403804 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0396652 |
| APP | amyloid beta (A4) precursor protein | 0.0395138 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 0.0391989 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0390659 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.03889 |
| EZR | ezrin | 0.0387364 |
| PRELID2 | PRELI domain containing 2 | 0.0383998 |
| FAT1 | FAT atypical cadherin 1 | 0.0381669 |
| DSCAM | Down syndrome cell adhesion molecule | 0.038022 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | 0.0377105 |
| COPA | coatomer protein complex, subunit alpha | 0.0376352 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0372338 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0369833 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0368011 |
| FLNA | filamin A, alpha | 0.0365882 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0364645 |
| NOP58 | NOP58 ribonucleoprotein | 0.0363654 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0361172 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0360932 |
| TXNRD1 | thioredoxin reductase 1 | 0.0356984 |
| MYOF | myoferlin | 0.0356191 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0355133 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0354521 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0354148 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0350852 |
| FNIP1 | folliculin interacting protein 1 | 0.0349216 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0344324 |
| CEP350 | centrosomal protein 350kDa | 0.0342169 |
| CRY1 | cryptochrome circadian clock 1 | 0.0340785 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0336109 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0336001 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0331435 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0330248 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.032638 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.032628 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0325911 |
| MKI67 | marker of proliferation Ki-67 | 0.0324201 |
| EMP1 | epithelial membrane protein 1 | 0.0323886 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0322847 |
| TPM3 | tropomyosin 3 | 0.0321456 |
| RUNX1 | runt-related transcription factor 1 | 0.0319436 |
| YTHDC1 | YTH domain containing 1 | 0.0319019 |
| AFDN | afadin, adherens junction formation factor | 0.0317501 |
| SDHA | succinate dehydrogenase complex, subunit A, flavoprotein (Fp) | 0.0314436 |
| RBM25 | RNA binding motif protein 25 | 0.0313986 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.0312704 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0312465 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0311591 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0306809 |
| TMEM87A | transmembrane protein 87A | 0.030405 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0301607 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0300231 |
| GOLGB1 | golgin B1 | 0.0298903 |
| SIRT1 | sirtuin 1 | 0.0298467 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0296115 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0295992 |
| ARRDC3 | arrestin domain containing 3 | 0.0293348 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0293202 |
| USP34 | ubiquitin specific peptidase 34 | 0.0292743 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0291755 |
| SFMBT2 | Scm-like with four mbt domains 2 | 0.028993 |
| CTBP2 | C-terminal binding protein 2 | 0.0289727 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.37794 |
| FN1 | fibronectin 1 | -0.156975 |
| NRG1 | neuregulin 1 | -0.135722 |
| VCL | vinculin | -0.118014 |
| HMGA2 | high mobility group AT-hook 2 | -0.0955785 |
| GLIS3 | GLIS family zinc finger 3 | -0.088866 |
| TMSB10 | thymosin beta 10 | -0.0840175 |
| NRP1 | neuropilin 1 | -0.0817377 |
| MT2A | metallothionein 2A | -0.0809155 |
| ASPH | aspartate beta-hydroxylase | -0.0795236 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0768211 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0731682 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0722106 |
| NTN4 | netrin 4 | -0.0716588 |
| FTL | ferritin, light polypeptide | -0.0701597 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0694517 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.063753 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0559146 |
| ITGA1 | integrin, alpha 1 | -0.0517799 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0503894 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0490245 |
| SYT1 | synaptotagmin I | -0.0478088 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0472194 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0468691 |
| PALLD | palladin, cytoskeletal associated protein | -0.0453294 |
| OSMR | oncostatin M receptor | -0.0449434 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0447636 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0446878 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0431336 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0427269 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0415397 |
| TMEM156 | transmembrane protein 156 | -0.0406883 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0401543 |
| RPLP1 | ribosomal protein, large, P1 | -0.0399526 |
| TOP1 | topoisomerase (DNA) I | -0.0395052 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.037623 |
| FOXP1 | forkhead box P1 | -0.0374673 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.037065 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0366538 |
| FHL2 | four and a half LIM domains 2 | -0.0360228 |
| RIGI | RNA sensor RIG-I | -0.0359113 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0356804 |
| IER3 | immediate early response 3 | -0.0356158 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0355541 |
| KLHL5 | kelch-like family member 5 | -0.035157 |
| TGFB1 | transforming growth factor, beta 1 | -0.0348752 |
| RAB31 | RAB31, member RAS oncogene family | -0.034779 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0345756 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.0342318 |
| RNF213 | ring finger protein 213 | -0.0329713 |
| RPS6 | ribosomal protein S6 | -0.032773 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0312989 |
| ETV1 | ets variant 1 | -0.0310748 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0309903 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0308613 |
| RPL35A | ribosomal protein L35a | -0.030636 |
| MAP1B | microtubule-associated protein 1B | -0.0303721 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0302121 |
| RPL37 | ribosomal protein L37 | -0.0300452 |
| SQSTM1 | sequestosome 1 | -0.0294575 |
| SEPTIN9 | septin 9 | -0.029445 |
| S100A6 | S100 calcium binding protein A6 | -0.0290665 |
| MX1 | MX dynamin-like GTPase 1 | -0.0290055 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | -0.0289155 |
| RPS27 | ribosomal protein S27 | -0.028709 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0284616 |
| ITGB5 | integrin, beta 5 | -0.0283979 |
| RPS20 | ribosomal protein S20 | -0.0282232 |
| MX2 | MX dynamin-like GTPase 2 | -0.0277754 |
| RPS19 | ribosomal protein S19 | -0.0276813 |
| RPL34 | ribosomal protein L34 | -0.0274965 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0274581 |
| MYO10 | myosin X | -0.0273549 |
| RPS21 | ribosomal protein S21 | -0.0272837 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | -0.0261748 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0260327 |
| HLA-B | major histocompatibility complex, class I, B | -0.0253867 |
| RPS25 | ribosomal protein S25 | -0.0252829 |
| RHEB | Ras homolog enriched in brain | -0.0251973 |
| NXN | nucleoredoxin | -0.0248503 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0248305 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0247883 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0244297 |
| RPS29 | ribosomal protein S29 | -0.0244016 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0239852 |
| RAI14 | retinoic acid induced 14 | -0.0238579 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0233593 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0231986 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0231808 |
| TPM4 | tropomyosin 4 | -0.0229228 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0228823 |
| H1-0 | H1.0 linker histone | -0.0228775 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0224318 |
| PELO | pelota homolog (Drosophila) | -0.0218942 |
| RPL37A | ribosomal protein L37a | -0.0218571 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0218198 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0217363 |
| AEBP2 | AE binding protein 2 | -0.0215483 |
| RPL36 | ribosomal protein L36 | -0.0213638 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0212253 |
