Alloxan Diabetes Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C0002152
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Genes

112 genes associated with the disease Alloxan Diabetes in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ACE angiotensin I converting enzyme
ACOT1 acyl-CoA thioesterase 1
ACOX1 acyl-CoA oxidase 1, palmitoyl
ACSL1 acyl-CoA synthetase long-chain family member 1
ADRA1A adrenoceptor alpha 1A
ADRB3 adrenoceptor beta 3
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1
AOC3 amine oxidase, copper containing 3
ATF3 activating transcription factor 3
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
ATP2A3 ATPase, Ca++ transporting, ubiquitous
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BDKRB1 bradykinin receptor B1
CASP3 caspase 3, apoptosis-related cysteine peptidase
CAT catalase
CAV1 caveolin 1, caveolae protein, 22kDa
CAV3 caveolin 3
CCL20 chemokine (C-C motif) ligand 20
CD68 CD68 molecule
CHRM2 cholinergic receptor, muscarinic 2
COX2
CPT1A carnitine palmitoyltransferase 1A (liver)
CPT1B carnitine palmitoyltransferase 1B (muscle)
CX3CL1 chemokine (C-X3-C motif) ligand 1
CYBA cytochrome b-245, alpha polypeptide
CYBB cytochrome b-245, beta polypeptide
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11
EDN1 endothelin 1
ESRRA estrogen-related receptor alpha
FAS Fas cell surface death receptor
FGF21 fibroblast growth factor 21
FOXO3 forkhead box O3
GCK glucokinase (hexokinase 4)
GPAM glycerol-3-phosphate acyltransferase, mitochondrial
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
GPX1 glutathione peroxidase 1
GSR glutathione reductase
HK1 hexokinase 1
HMOX1 heme oxygenase 1
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
IAPP islet amyloid polypeptide
ICAM1 intercellular adhesion molecule 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IL1B interleukin 1, beta
IL6 interleukin 6
INSR insulin receptor
IRS1 insulin receptor substrate 1
IRS2 insulin receptor substrate 2
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11
LEP leptin
LEPR leptin receptor
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MFGE8 milk fat globule-EGF factor 8 protein
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MPO myeloperoxidase
NCF1 neutrophil cytosolic factor 1
ND1
NEUROD1 neuronal differentiation 1
NKX6-1 NK6 homeobox 1
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NQO1 NAD(P)H dehydrogenase, quinone 1
PAX6 paired box 6
PC pyruvate carboxylase
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PCSK2 proprotein convertase subtilisin/kexin type 2
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PDX1 pancreatic and duodenal homeobox 1
PFKM phosphofructokinase, muscle
PKLR pyruvate kinase, liver and RBC
PPARA peroxisome proliferator-activated receptor alpha
PPARG peroxisome proliferator-activated receptor gamma
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PRKCA protein kinase C, alpha
PRKCD protein kinase C, delta
PRKCE protein kinase C, epsilon
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
REN renin
S100A6 S100 calcium binding protein A6
S1PR2 sphingosine-1-phosphate receptor 2
S1PR4 sphingosine-1-phosphate receptor 4
S1PR5 sphingosine-1-phosphate receptor 5
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SIRT1 sirtuin 1
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
SNAP25 synaptosomal-associated protein, 25kDa
SOD1 superoxide dismutase 1, soluble
SOD2 superoxide dismutase 2, mitochondrial
SREBF1 sterol regulatory element binding transcription factor 1
STS steroid sulfatase (microsomal), isozyme S
TGFB1 transforming growth factor, beta 1
TIMP1 TIMP metallopeptidase inhibitor 1
TIMP2 TIMP metallopeptidase inhibitor 2
TNF tumor necrosis factor
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TP53 tumor protein p53
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
VEGFA vascular endothelial growth factor A
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta