Alloxan Gene Set

Dataset CTD Gene-Chemical Interactions
Category physical interactions
Type chemical
Description A member of the class of pyrimidones, the structure of which is that of perhydropyrimidine substituted at C-2, -4, -5 and -6 by oxo groups. (Chemical Entities of Biological Interest Ontology, CHEBI_76451)
External Link http://ctdbase.org/detail.go?type=chem&acc=D000496
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Genes

24 genes/proteins interacting with the chemical Alloxan from the curated CTD Gene-Chemical Interactions dataset.

Symbol Name
ACOX1 acyl-CoA oxidase 1, palmitoyl
APAF1 apoptotic peptidase activating factor 1
BAD BCL2-associated agonist of cell death
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CAT catalase
CCL2 chemokine (C-C motif) ligand 2
CYCS cytochrome c, somatic
GSR glutathione reductase
ICAM1 intercellular adhesion molecule 1
IL12B interleukin 12B
IL6 interleukin 6
INSR insulin receptor
IRS1 insulin receptor substrate 1
MPO myeloperoxidase
PARP1 poly (ADP-ribose) polymerase 1
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4
SOD1 superoxide dismutase 1, soluble
TNF tumor necrosis factor
XDH xanthine dehydrogenase