| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Almonertinib (hydrochloride) perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Almonertinib (hydrochloride)_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LAMB3 | laminin, beta 3 | 0.0978602 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0916032 |
| EFNA5 | ephrin-A5 | 0.0851858 |
| LAMC2 | laminin, gamma 2 | 0.0778592 |
| APOL1 | apolipoprotein L, 1 | 0.0755054 |
| B2M | beta-2-microglobulin | 0.0723604 |
| LAMA4 | laminin, alpha 4 | 0.0715508 |
| CP | ceruloplasmin (ferroxidase) | 0.0711988 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.067898 |
| MMP7 | matrix metallopeptidase 7 | 0.0678129 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0655163 |
| KRT19 | keratin 19, type I | 0.064955 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0537687 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0536273 |
| S100A6 | S100 calcium binding protein A6 | 0.0491204 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0481958 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0476766 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0475652 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0461105 |
| HLA-B | major histocompatibility complex, class I, B | 0.0453788 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0434275 |
| EGR1 | early growth response 1 | 0.043302 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0403416 |
| SACK1A | scaffolding CK1 anchoring protein A | 0.0388176 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0383748 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0373122 |
| RPL35A | ribosomal protein L35a | 0.0366539 |
| RAD51B | RAD51 paralog B | 0.0366298 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0364947 |
| MYO1E | myosin IE | 0.0355523 |
| LMO7 | LIM domain 7 | 0.035221 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | 0.0341215 |
| LCN2 | lipocalin 2 | 0.0337023 |
| PLAT | plasminogen activator, tissue | 0.0335516 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0326924 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0324351 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0323239 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0317196 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0310493 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.030536 |
| TMC5 | transmembrane channel-like 5 | 0.0299166 |
| CDK6 | cyclin-dependent kinase 6 | 0.0297276 |
| NRG3 | neuregulin 3 | 0.0291562 |
| RPL37A | ribosomal protein L37a | 0.0291287 |
| RASAL2 | RAS protein activator like 2 | 0.02874 |
| RPS8 | ribosomal protein S8 | 0.0280703 |
| RPL34 | ribosomal protein L34 | 0.0279207 |
| EHBP1 | EH domain binding protein 1 | 0.0276924 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.027575 |
| HMGA2 | high mobility group AT-hook 2 | 0.0273829 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0273318 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0271557 |
| ITGA6 | integrin, alpha 6 | 0.0270883 |
| HLA-A | major histocompatibility complex, class I, A | 0.0270466 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | 0.0266424 |
| C3 | complement component 3 | 0.0261535 |
| RPL31 | ribosomal protein L31 | 0.0258529 |
| RPS17 | ribosomal protein S17 | 0.0257555 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0254584 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0251657 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0250442 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0248139 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0245516 |
| OSMR | oncostatin M receptor | 0.0244431 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0243799 |
| RCOR1 | REST corepressor 1 | 0.0240814 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0240045 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0237064 |
| ATXN1 | ataxin 1 | 0.0235234 |
| KYNU | kynureninase | 0.023174 |
| NCKAP5 | NCK-associated protein 5 | 0.0230529 |
| RPS3 | ribosomal protein S3 | 0.0230517 |
| NUMB | numb homolog (Drosophila) | 0.0228772 |
| HDAC9 | histone deacetylase 9 | 0.0224376 |
| PRKCA | protein kinase C, alpha | 0.0221041 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0220832 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0220226 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0220215 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0219272 |
| VCL | vinculin | 0.0218083 |
| DNAH11 | dynein, axonemal, heavy chain 11 | 0.0217918 |
| RNF213 | ring finger protein 213 | 0.0217782 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0213277 |
| RPL9 | ribosomal protein L9 | 0.0213137 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0213094 |
| PSEN1 | presenilin 1 | 0.0209716 |
| ADAM8 | ADAM metallopeptidase domain 8 | 0.0209007 |
| TMSB10 | thymosin beta 10 | 0.0206879 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0206133 |
| CMIP | c-Maf inducing protein | 0.0206075 |
| EGFR | epidermal growth factor receptor | 0.0204065 |
| GREB1L | growth regulation by estrogen in breast cancer-like | 0.0202634 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0199859 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0197555 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0194256 |
| RPS21 | ribosomal protein S21 | 0.019092 |
| SVIL | supervillin | 0.0190874 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0190317 |
| KIF13B | kinesin family member 13B | 0.0188452 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0188284 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.208609 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.175851 |
| TSC22D2 | TSC22 domain family, member 2 | -0.12389 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.123639 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.099645 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0868691 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0808666 |
| FAM13A | family with sequence similarity 13, member A | -0.0779218 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0750983 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.07459 |
| RBM39 | RNA binding motif protein 39 | -0.0732863 |
| SPAG9 | sperm associated antigen 9 | -0.0662193 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0633418 |
| OGA | O-GlcNAcase | -0.0605924 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0591159 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0589906 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0588448 |
| MT1X | metallothionein 1X | -0.0581567 |
| PTMA | prothymosin, alpha | -0.0565339 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0554469 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0543843 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0498126 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0493122 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0475789 |
| CCNL1 | cyclin L1 | -0.0470368 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0468359 |
| CCNY | cyclin Y | -0.0466748 |
| FTL | ferritin, light polypeptide | -0.0451902 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0443364 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0441633 |
| ZNF292 | zinc finger protein 292 | -0.0440351 |
| RIOK3 | RIO kinase 3 | -0.0435802 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0431911 |
| UBC | ubiquitin C | -0.0428193 |
| HELZ | helicase with zinc finger | -0.042546 |
| USP3 | ubiquitin specific peptidase 3 | -0.0421961 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0414851 |
| RLF | rearranged L-myc fusion | -0.0402191 |
| NDRG1 | N-myc downstream regulated 1 | -0.0391218 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0382265 |
| FAM162A | family with sequence similarity 162, member A | -0.0378618 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0372127 |
| TFG | TRK-fused gene | -0.0371409 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0369908 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0367579 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | -0.0367033 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | -0.0361109 |
| TOP1 | topoisomerase (DNA) I | -0.0358625 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0357292 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0351433 |
| CANX | calnexin | -0.0347358 |
| NUP58 | nucleoporin 58 | -0.0346722 |
| FNBP1L | formin binding protein 1-like | -0.0340743 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0340288 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | -0.0333417 |
| HOOK2 | hook microtubule-tethering protein 2 | -0.033007 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0320442 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0315832 |
| COPA | coatomer protein complex, subunit alpha | -0.0310965 |
| FOSL1 | FOS-like antigen 1 | -0.030473 |
| MATR3 | matrin 3 | -0.0301711 |
| PCBP2 | poly(rC) binding protein 2 | -0.0299645 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.02981 |
| CDC73 | cell division cycle 73 | -0.0298049 |
| ATP11B | ATPase, class VI, type 11B | -0.0296615 |
| RNF149 | ring finger protein 149 | -0.0296356 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0294396 |
| WDR45B | WD repeat domain 45B | -0.0294246 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0292919 |
| RTN4 | reticulon 4 | -0.028852 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0285266 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0284014 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0283169 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.0282599 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0278122 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0272424 |
| MYO1B | myosin IB | -0.0269645 |
| OSBPL9 | oxysterol binding protein-like 9 | -0.0268927 |
| TMEM123 | transmembrane protein 123 | -0.0267691 |
| YTHDC1 | YTH domain containing 1 | -0.0266844 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0266548 |
| ADM | adrenomedullin | -0.0263723 |
| QKI | QKI, KH domain containing, RNA binding | -0.0261701 |
| ABI1 | abl-interactor 1 | -0.0256817 |
| VEZT | vezatin, adherens junctions transmembrane protein | -0.0255619 |
| MYOF | myoferlin | -0.0255031 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0254794 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | -0.025303 |
| SRP54 | signal recognition particle 54kDa | -0.0252929 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0246929 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0245186 |
| SUCO | SUN domain containing ossification factor | -0.02421 |
| NPTN | neuroplastin | -0.0242054 |
| ARRDC3 | arrestin domain containing 3 | -0.024197 |
| MAP1B | microtubule-associated protein 1B | -0.0241572 |
| ZNF207 | zinc finger protein 207 | -0.0241316 |
| RYBP | RING1 and YY1 binding protein | -0.0240528 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.0238437 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0237364 |
| BRD2 | bromodomain containing 2 | -0.023569 |
