| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Almonertinib (hydrochloride) perturbation in LOX-IMVI cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Almonertinib (hydrochloride)_LOX-IMVI drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.131322 |
| RPS12 | ribosomal protein S12 | 0.123223 |
| RPS3 | ribosomal protein S3 | 0.0890521 |
| RPS2 | ribosomal protein S2 | 0.0780346 |
| FTL | ferritin, light polypeptide | 0.0686377 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0661367 |
| MSN | moesin | 0.0652771 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0634244 |
| LIMA1 | LIM domain and actin binding 1 | 0.0593456 |
| RPL12 | ribosomal protein L12 | 0.0569191 |
| RPS17 | ribosomal protein S17 | 0.0559899 |
| RPL35A | ribosomal protein L35a | 0.0541445 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0507694 |
| RPL37A | ribosomal protein L37a | 0.0504732 |
| POTEF | POTE ankyrin domain family, member F | 0.0465725 |
| YBX3 | Y box binding protein 3 | 0.0453955 |
| STC1 | stanniocalcin 1 | 0.0416803 |
| CALD1 | caldesmon 1 | 0.0405252 |
| RPS8 | ribosomal protein S8 | 0.0392727 |
| DTNA | dystrobrevin, alpha | 0.0359183 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0349344 |
| RPL36 | ribosomal protein L36 | 0.0344796 |
| RPS19 | ribosomal protein S19 | 0.0340612 |
| RPLP2 | ribosomal protein, large, P2 | 0.0326483 |
| ENKUR | enkurin, TRPC channel interacting protein | 0.0323178 |
| RPL9 | ribosomal protein L9 | 0.0317487 |
| RACK1 | receptor for activated C kinase 1 | 0.030621 |
| CD44 | CD44 molecule (Indian blood group) | 0.029623 |
| RPS7 | ribosomal protein S7 | 0.0294723 |
| RPL26 | ribosomal protein L26 | 0.02928 |
| RPS13 | ribosomal protein S13 | 0.0287999 |
| TPM3 | tropomyosin 3 | 0.0285218 |
| KISS1 | KiSS-1 metastasis-suppressor | 0.028418 |
| RPL30 | ribosomal protein L30 | 0.0265398 |
| RPL31 | ribosomal protein L31 | 0.0249847 |
| RPL5 | ribosomal protein L5 | 0.0246829 |
| RPL36A | ribosomal protein L36a | 0.0242584 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0241773 |
| CDK17 | cyclin-dependent kinase 17 | 0.0230367 |
| ESM1 | endothelial cell-specific molecule 1 | 0.0223549 |
| YBX1 | Y box binding protein 1 | 0.0223282 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0217059 |
| RPL23 | ribosomal protein L23 | 0.021352 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0210944 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0205759 |
| SET | SET nuclear proto-oncogene | 0.0205733 |
| RPLP0 | ribosomal protein, large, P0 | 0.0204392 |
| RPS14 | ribosomal protein S14 | 0.0201454 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0196504 |
| RPL18 | ribosomal protein L18 | 0.0193634 |
| CASP4 | caspase 4, apoptosis-related cysteine peptidase | 0.0192075 |
| ADAM19 | ADAM metallopeptidase domain 19 | 0.0191769 |
| LDHA | lactate dehydrogenase A | 0.0189267 |
| TXNIP | thioredoxin interacting protein | 0.0183386 |
| ATP5F1E | ATP synthase F1 subunit epsilon | 0.0182474 |
| PFN1 | profilin 1 | 0.0180983 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0175598 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0167417 |
| RPS4X | ribosomal protein S4, X-linked | 0.0166749 |
| RPL27 | ribosomal protein L27 | 0.016606 |
| RPS27 | ribosomal protein S27 | 0.0164885 |
| RPL21 | ribosomal protein L21 | 0.0164374 |
| FOSL1 | FOS-like antigen 1 | 0.0164331 |
| SLC25A3 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 | 0.0163859 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0163717 |
| TXNRD1 | thioredoxin reductase 1 | 0.0162635 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | 0.0160974 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | 0.0158921 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0155844 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0151958 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | 0.0150537 |
| MT1E | metallothionein 1E | 0.0149545 |
| RPL27A | ribosomal protein L27a | 0.014931 |
| WWC1 | WW and C2 domain containing 1 | 0.0147735 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | 0.0145033 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.0144659 |
| ENO1 | enolase 1, (alpha) | 0.0140463 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0140291 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0138856 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.0136852 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0136439 |
| RASA2 | RAS p21 protein activator 2 | 0.0135191 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0134322 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0133802 |
| RPL28 | ribosomal protein L28 | 0.0132764 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.0130531 |
| SAMD3 | sterile alpha motif domain containing 3 | 0.0130461 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0130162 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0129281 |
| COX6C | cytochrome c oxidase subunit VIc | 0.0129143 |
| SHANK1 | SH3 and multiple ankyrin repeat domains 1 | 0.0129083 |
| PKIA | protein kinase (cAMP-dependent, catalytic) inhibitor alpha | 0.0128669 |
| CHMP5 | charged multivesicular body protein 5 | 0.0128265 |
| MT1X | metallothionein 1X | 0.0125767 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0124968 |
| RPL7A | ribosomal protein L7a | 0.0124016 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | 0.0122819 |
| CCN2 | cellular communication network factor 2 | 0.0122766 |
| B2M | beta-2-microglobulin | 0.0120155 |
| RPL11 | ribosomal protein L11 | 0.0119879 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.194208 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.193342 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.129589 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.120507 |
| AHNAK | AHNAK nucleoprotein | -0.114864 |
| GPC6 | glypican 6 | -0.111518 |
| MMP12 | matrix metallopeptidase 12 | -0.111495 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0957457 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.089478 |
| PTMA | prothymosin, alpha | -0.0807996 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0789293 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0679394 |
| TMSB10 | thymosin beta 10 | -0.0661661 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0659996 |
| DST | dystonin | -0.065499 |
| PTK2 | protein tyrosine kinase 2 | -0.0649717 |
| INTS6 | integrator complex subunit 6 | -0.0633953 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0575417 |
| PTCHD4 | patched domain containing 4 | -0.0567096 |
| EFNA5 | ephrin-A5 | -0.0563226 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0562783 |
| ACTG1 | actin gamma 1 | -0.0561582 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0551355 |
| SPAG9 | sperm associated antigen 9 | -0.0489701 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0476576 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0468922 |
| USP34 | ubiquitin specific peptidase 34 | -0.0466614 |
| FUS | FUS RNA binding protein | -0.046624 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0460095 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0459721 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0456941 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0442257 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0436845 |
| PARD3 | par-3 family cell polarity regulator | -0.0428961 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0426978 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0411806 |
| TAOK1 | TAO kinase 1 | -0.0403861 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0393852 |
| NABP1 | nucleic acid binding protein 1 | -0.038898 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0375991 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0373682 |
| ANXA2 | annexin A2 | -0.0371197 |
| MED13L | mediator complex subunit 13-like | -0.0369504 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0364864 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.0361515 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0360821 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.036049 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0359857 |
| CAVIN1 | caveolae associated protein 1 | -0.0357806 |
| GNAS | GNAS complex locus | -0.0356168 |
| CDH13 | cadherin 13 | -0.0351778 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0350928 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0348186 |
| ATXN1 | ataxin 1 | -0.0344699 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0341478 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0329887 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0329496 |
| PRKCE | protein kinase C, epsilon | -0.0327262 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0325709 |
| EMP1 | epithelial membrane protein 1 | -0.0324542 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0322868 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.0322452 |
| FBXO11 | F-box protein 11 | -0.0322315 |
| DEK | DEK proto-oncogene | -0.0318964 |
| SP100 | SP100 nuclear antigen | -0.031801 |
| NAV1 | neuron navigator 1 | -0.0315837 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0314947 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0312981 |
| SSH2 | slingshot protein phosphatase 2 | -0.0311997 |
| ZNF804A | zinc finger protein 804A | -0.0309619 |
| CD2AP | CD2-associated protein | -0.0308704 |
| MYOF | myoferlin | -0.0305095 |
| CUX1 | cut-like homeobox 1 | -0.0303693 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0300527 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0300251 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0300027 |
| MKI67 | marker of proliferation Ki-67 | -0.0300026 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0298225 |
| VCL | vinculin | -0.0297799 |
| CDK12 | cyclin-dependent kinase 12 | -0.0293597 |
| RPL8 | ribosomal protein L8 | -0.029235 |
| C2CD2 | C2 calcium-dependent domain containing 2 | -0.0291208 |
| RBM39 | RNA binding motif protein 39 | -0.0291113 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0288676 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0286796 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0286609 |
| EGR1 | early growth response 1 | -0.0285519 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0285181 |
| H1-0 | H1.0 linker histone | -0.0283836 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0283365 |
| BNC2 | basonuclin 2 | -0.0282773 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0281188 |
| SETD5 | SET domain containing 5 | -0.0279644 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0279304 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0277843 |
| NF1 | neurofibromin 1 | -0.0276167 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.0275616 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0274436 |
| CANX | calnexin | -0.0273672 |
| PHF3 | PHD finger protein 3 | -0.0273398 |
