| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Almonertinib (hydrochloride) perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Almonertinib (hydrochloride)_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | 0.119372 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.117723 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0965273 |
| RPS12 | ribosomal protein S12 | 0.096471 |
| FTL | ferritin, light polypeptide | 0.0731004 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0729797 |
| MT2A | metallothionein 2A | 0.0711168 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0681546 |
| LDHA | lactate dehydrogenase A | 0.0676657 |
| AREG | amphiregulin | 0.0661666 |
| B2M | beta-2-microglobulin | 0.0580583 |
| RPS3 | ribosomal protein S3 | 0.057639 |
| NDRG1 | N-myc downstream regulated 1 | 0.0574091 |
| RPL35A | ribosomal protein L35a | 0.0552949 |
| RPS2 | ribosomal protein S2 | 0.0542563 |
| KRT18 | keratin 18, type I | 0.051637 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0509572 |
| RPS8 | ribosomal protein S8 | 0.0484642 |
| MUC13 | mucin 13, cell surface associated | 0.0475183 |
| RPL37A | ribosomal protein L37a | 0.0466438 |
| EPCAM | epithelial cell adhesion molecule | 0.0461708 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0439914 |
| PGK1 | phosphoglycerate kinase 1 | 0.0439087 |
| EREG | epiregulin | 0.0432955 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0418081 |
| ENO1 | enolase 1, (alpha) | 0.0394196 |
| KRT8 | keratin 8, type II | 0.0381283 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0350595 |
| ANXA1 | annexin A1 | 0.0342413 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0334369 |
| RPL9 | ribosomal protein L9 | 0.0325217 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | 0.0312171 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0302669 |
| RPL26 | ribosomal protein L26 | 0.0294154 |
| VEGFA | vascular endothelial growth factor A | 0.0280862 |
| YBX1 | Y box binding protein 1 | 0.0279393 |
| MUC17 | mucin 17, cell surface associated | 0.0276275 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0265989 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | 0.0264946 |
| LMO7 | LIM domain 7 | 0.0263381 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0261239 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0256771 |
| POTEF | POTE ankyrin domain family, member F | 0.0256751 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0249977 |
| FAM13A | family with sequence similarity 13, member A | 0.0248851 |
| RPS7 | ribosomal protein S7 | 0.0247857 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.024678 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0239448 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0238487 |
| CSTB | cystatin B (stefin B) | 0.0235638 |
| RPL18 | ribosomal protein L18 | 0.0230814 |
| WDR45B | WD repeat domain 45B | 0.0223872 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0220456 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0219701 |
| CLTC | clathrin, heavy chain (Hc) | 0.0217881 |
| OCIAD2 | OCIA domain containing 2 | 0.0217674 |
| TMC5 | transmembrane channel-like 5 | 0.0217605 |
| EMP1 | epithelial membrane protein 1 | 0.021457 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0210591 |
| CENPF | centromere protein F, 350/400kDa | 0.02094 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.0207565 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0206711 |
| VIM | vimentin | 0.0204659 |
| RPL3 | ribosomal protein L3 | 0.020259 |
| CLDN4 | claudin 4 | 0.0202498 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0202132 |
| RPS19 | ribosomal protein S19 | 0.0195621 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0188935 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0188899 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.018811 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.0185642 |
| MXD1 | MAX dimerization protein 1 | 0.0184339 |
| SRP14 | signal recognition particle 14kDa (homologous Alu RNA binding protein) | 0.0184133 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0182126 |
| JUN | jun proto-oncogene | 0.0181876 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0181167 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0181119 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0180486 |
| TPM3 | tropomyosin 3 | 0.0180435 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0180334 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | 0.0180264 |
| SLK | STE20-like kinase | 0.0178704 |
| LAMB3 | laminin, beta 3 | 0.0176048 |
| RPS17 | ribosomal protein S17 | 0.0172815 |
| RPL30 | ribosomal protein L30 | 0.0166648 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0166532 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0166292 |
| RPLP0 | ribosomal protein, large, P0 | 0.0164743 |
| S100A6 | S100 calcium binding protein A6 | 0.0162037 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0161772 |
| MLF1 | myeloid leukemia factor 1 | 0.016176 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0159393 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | 0.0159299 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0159045 |
| UBE2B | ubiquitin-conjugating enzyme E2B | 0.0157839 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0157273 |
| BMP4 | bone morphogenetic protein 4 | 0.0156965 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.015696 |
| RPS13 | ribosomal protein S13 | 0.0154705 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0153767 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.160504 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.129597 |
| NPSR1 | neuropeptide S receptor 1 | -0.12392 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.102488 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.100348 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0898307 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0863925 |
| AHNAK | AHNAK nucleoprotein | -0.0843879 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0814691 |
| GPHN | gephyrin | -0.0787291 |
| CADPS | Ca++-dependent secretion activator | -0.0730945 |
| TMSB10 | thymosin beta 10 | -0.0726842 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0696784 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.0696601 |
| VCL | vinculin | -0.0672533 |
| SMYD3 | SET and MYND domain containing 3 | -0.0644279 |
| TNS4 | tensin 4 | -0.0623598 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0593754 |
| PTEN | phosphatase and tensin homolog | -0.0574876 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0551552 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0523995 |
| RNF43 | ring finger protein 43 | -0.0521271 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0499672 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0499415 |
| CCND1 | cyclin D1 | -0.0493026 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0475372 |
| MECOM | MDS1 and EVI1 complex locus | -0.0472406 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0471459 |
| NFIA | nuclear factor I/A | -0.0468789 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0465095 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0458816 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0456976 |
| MSI2 | musashi RNA-binding protein 2 | -0.0456527 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0452499 |
| ATXN1 | ataxin 1 | -0.0441922 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0441256 |
| FOXO1 | forkhead box O1 | -0.0440827 |
| FHIT | fragile histidine triad | -0.0437584 |
| SAMD5 | sterile alpha motif domain containing 5 | -0.0431926 |
| ANXA2 | annexin A2 | -0.0428876 |
| PARD3 | par-3 family cell polarity regulator | -0.0419914 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.041758 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0413622 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0413075 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0411302 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.040357 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0403187 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0400278 |
| RAB10 | RAB10, member RAS oncogene family | -0.0396433 |
| RPS23 | ribosomal protein S23 | -0.0392907 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0389317 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0388683 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0384423 |
| FOXP1 | forkhead box P1 | -0.0384179 |
| BPTF | bromodomain PHD finger transcription factor | -0.0383467 |
| S100A10 | S100 calcium binding protein A10 | -0.0381651 |
| H1-0 | H1.0 linker histone | -0.0376456 |
| DEK | DEK proto-oncogene | -0.037599 |
| ITGA6 | integrin, alpha 6 | -0.0372785 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0371502 |
| USP34 | ubiquitin specific peptidase 34 | -0.0369374 |
| MAP7 | microtubule-associated protein 7 | -0.0363782 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0362957 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.03628 |
| MYO1D | myosin ID | -0.0361323 |
| RPS6 | ribosomal protein S6 | -0.0361045 |
| PKP4 | plakophilin 4 | -0.0360532 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0360293 |
| FRMD5 | FERM domain containing 5 | -0.0358068 |
| NRXN3 | neurexin 3 | -0.0357019 |
| PARD3B | par-3 family cell polarity regulator beta | -0.035554 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0352493 |
| PIGR | polymeric immunoglobulin receptor | -0.0349801 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.0349223 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0348633 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0348601 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | -0.0348222 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0342464 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0339788 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0338065 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0335909 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0335879 |
| NHSL1 | NHS-like 1 | -0.0334511 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0330451 |
| JMJD1C | jumonji domain containing 1C | -0.0330259 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | -0.0330011 |
| CUX1 | cut-like homeobox 1 | -0.0329131 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0328902 |
| SH3D19 | SH3 domain containing 19 | -0.0328286 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0326781 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0325304 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0321392 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0321212 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0320783 |
| MED13L | mediator complex subunit 13-like | -0.032065 |
| CD44 | CD44 molecule (Indian blood group) | -0.0317073 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0316444 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0314282 |
| SBF2 | SET binding factor 2 | -0.031215 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.03111 |
