| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Almonertinib (hydrochloride) perturbation in Panc 03.27 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Almonertinib (hydrochloride)_Panc 03.27 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | 0.160472 |
| LMO7 | LIM domain 7 | 0.11399 |
| MYO6 | myosin VI | 0.110073 |
| RPL35A | ribosomal protein L35a | 0.104749 |
| TSC22D2 | TSC22 domain family, member 2 | 0.100365 |
| NDRG1 | N-myc downstream regulated 1 | 0.0812418 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0762984 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0711919 |
| HMGA1 | high mobility group AT-hook 1 | 0.0698356 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0688876 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0678986 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0669314 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0659729 |
| FAM3C | family with sequence similarity 3, member C | 0.0637922 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0634628 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0604339 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | 0.0588683 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0586411 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0550639 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0538606 |
| RPS12 | ribosomal protein S12 | 0.0533927 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0508396 |
| JMJD1C | jumonji domain containing 1C | 0.0475155 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0460007 |
| CLDN1 | claudin 1 | 0.0455616 |
| MYO1E | myosin IE | 0.0452236 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0447913 |
| WFDC2 | WAP four-disulfide core domain 2 | 0.0445195 |
| CLDN4 | claudin 4 | 0.0439433 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0434873 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.0427986 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0416001 |
| RPS2 | ribosomal protein S2 | 0.0408652 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0408547 |
| KRT19 | keratin 19, type I | 0.0404238 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0399842 |
| YBX3 | Y box binding protein 3 | 0.0394804 |
| PTMA | prothymosin, alpha | 0.0387821 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0383458 |
| INTS6 | integrator complex subunit 6 | 0.0382402 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0381802 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0379576 |
| PLPP6 | phospholipid phosphatase 6 | 0.0379142 |
| AREG | amphiregulin | 0.0370772 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0366614 |
| RCOR1 | REST corepressor 1 | 0.0365945 |
| MACC1 | metastasis associated in colon cancer 1 | 0.03615 |
| FTL | ferritin, light polypeptide | 0.0355415 |
| HLA-A | major histocompatibility complex, class I, A | 0.035159 |
| RBM39 | RNA binding motif protein 39 | 0.0349391 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0346289 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0345184 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0342377 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.033755 |
| JUP | junction plakoglobin | 0.0335948 |
| ATF3 | activating transcription factor 3 | 0.033295 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0323966 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0320447 |
| ANXA1 | annexin A1 | 0.0308238 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0304605 |
| PLAU | plasminogen activator, urokinase | 0.030408 |
| RPS8 | ribosomal protein S8 | 0.0303879 |
| SIK3 | SIK family kinase 3 | 0.0297331 |
| DUSP5 | dual specificity phosphatase 5 | 0.029277 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0292003 |
| RPS3 | ribosomal protein S3 | 0.0291839 |
| AFDN | afadin, adherens junction formation factor | 0.0287102 |
| MYO5B | myosin VB | 0.0279081 |
| RPS21 | ribosomal protein S21 | 0.027767 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0277132 |
| LAMA4 | laminin, alpha 4 | 0.027606 |
| TJP1 | tight junction protein 1 | 0.0275467 |
| PCDH1 | protocadherin 1 | 0.0274906 |
| RIMKLB | ribosomal modification protein rimK-like family member B | 0.0269835 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0268607 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 0.0265547 |
| BRD4 | bromodomain containing 4 | 0.0260527 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0257531 |
| DHX36 | DEAH (Asp-Glu-Ala-His) box polypeptide 36 | 0.0256395 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | 0.0255157 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | 0.0251359 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0250713 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0250678 |
| KLF6 | Kruppel-like factor 6 | 0.0250615 |
| CCNL1 | cyclin L1 | 0.0248667 |
| PARD3 | par-3 family cell polarity regulator | 0.0248379 |
| SPAG9 | sperm associated antigen 9 | 0.024836 |
| FMNL2 | formin-like 2 | 0.0244304 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.024313 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0238327 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0237366 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0234814 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0234018 |
| PLK2 | polo-like kinase 2 | 0.0228139 |
| RPL12 | ribosomal protein L12 | 0.0228113 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0227232 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0224077 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0223188 |
| FAM13A | family with sequence similarity 13, member A | 0.0222846 |
| NTN4 | netrin 4 | 0.0220781 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.29655 |
| AHNAK | AHNAK nucleoprotein | -0.163577 |
| UBC | ubiquitin C | -0.0879289 |
| TPM4 | tropomyosin 4 | -0.0749345 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0694844 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0652125 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0589301 |
| KRT17 | keratin 17, type I | -0.0586933 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0565627 |
| ACTG1 | actin gamma 1 | -0.0550522 |
| RPLP1 | ribosomal protein, large, P1 | -0.0545035 |
| CANX | calnexin | -0.0533514 |
| KRT8 | keratin 8, type II | -0.051708 |
| DIAPH3 | diaphanous-related formin 3 | -0.0511028 |
| DEK | DEK proto-oncogene | -0.0489382 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0472854 |
| ACTN4 | actinin, alpha 4 | -0.0449082 |
| SMAD3 | SMAD family member 3 | -0.0448991 |
| KRT7 | keratin 7, type II | -0.0447544 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0437432 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0419256 |
| CDCP1 | CUB domain containing protein 1 | -0.041186 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0409619 |
| RPS29 | ribosomal protein S29 | -0.0402423 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0401613 |
| RPS15 | ribosomal protein S15 | -0.0399686 |
| THBS1 | thrombospondin 1 | -0.03961 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0386734 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.037488 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0374583 |
| EHF | ets homologous factor | -0.0363843 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0355526 |
| SDC4 | syndecan 4 | -0.0354781 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0354606 |
| RPS23 | ribosomal protein S23 | -0.0354275 |
| S100A10 | S100 calcium binding protein A10 | -0.0347084 |
| ENO1 | enolase 1, (alpha) | -0.0342944 |
| HLA-C | major histocompatibility complex, class I, C | -0.034044 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0339819 |
| TMSB4X | thymosin beta 4, X-linked | -0.0338069 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0337646 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0336369 |
| MKI67 | marker of proliferation Ki-67 | -0.0329097 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0321703 |
| ETNK1 | ethanolamine kinase 1 | -0.0319794 |
| CDK12 | cyclin-dependent kinase 12 | -0.0306808 |
| CALU | calumenin | -0.0306513 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0305676 |
| PLAT | plasminogen activator, tissue | -0.0304989 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.0303294 |
| TXNRD1 | thioredoxin reductase 1 | -0.0301988 |
| AFAP1 | actin filament associated protein 1 | -0.0298866 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | -0.0296971 |
| EZR | ezrin | -0.029522 |
| MECOM | MDS1 and EVI1 complex locus | -0.0294921 |
| TC2N | tandem C2 domains, nuclear | -0.0294724 |
| RPL23 | ribosomal protein L23 | -0.0291849 |
| PLSCR1 | phospholipid scramblase 1 | -0.0287932 |
| ASPH | aspartate beta-hydroxylase | -0.0284312 |
| ATAD2 | ATPase family, AAA domain containing 2 | -0.0282884 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0279175 |
| STK24 | serine/threonine kinase 24 | -0.027862 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0271793 |
| MT2A | metallothionein 2A | -0.0270724 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0270687 |
| PHF3 | PHD finger protein 3 | -0.027018 |
| FRMD5 | FERM domain containing 5 | -0.0268521 |
| NAV2 | neuron navigator 2 | -0.0267419 |
| RPL4 | ribosomal protein L4 | -0.0264236 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0264213 |
| HMGB2 | high mobility group box 2 | -0.0263921 |
| SMYD3 | SET and MYND domain containing 3 | -0.0263752 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0261603 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.026123 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0255043 |
| RAD21 | RAD21 homolog (S. pombe) | -0.025305 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0251721 |
| ZFR | zinc finger RNA binding protein | -0.0250745 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0246866 |
| FOSL1 | FOS-like antigen 1 | -0.0244266 |
| XRN1 | 5'-3' exoribonuclease 1 | -0.0243833 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.024312 |
| ATXN7 | ataxin 7 | -0.0242787 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0242184 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0241215 |
| ZDHHC20 | zinc finger, DHHC-type containing 20 | -0.0240655 |
| MX1 | MX dynamin-like GTPase 1 | -0.0238961 |
| RAD51B | RAD51 paralog B | -0.0238414 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0237166 |
| RPL19 | ribosomal protein L19 | -0.0236448 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0234115 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0231791 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0231432 |
| ATXN1 | ataxin 1 | -0.0227429 |
| IL6ST | interleukin 6 signal transducer | -0.0226494 |
| RIOK3 | RIO kinase 3 | -0.022633 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | -0.0224519 |
| NUP214 | nucleoporin 214kDa | -0.0222381 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0221678 |
| NIBAN2 | niban apoptosis regulator 2 | -0.0221415 |
