| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Almonertinib (mesylate) perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Almonertinib (mesylate)_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MEIS2 | Meis homeobox 2 | 0.0824815 |
| IFNGR1 | interferon gamma receptor 1 | 0.0722894 |
| VMP1 | vacuole membrane protein 1 | 0.0717165 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0713911 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0678864 |
| VCL | vinculin | 0.0616727 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.0585104 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0582659 |
| BICRAL | BICRA like chromatin remodeling complex associated protein | 0.057828 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0575061 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0568504 |
| CMIP | c-Maf inducing protein | 0.0561257 |
| FAT1 | FAT atypical cadherin 1 | 0.0543267 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0539082 |
| TRERF1 | transcriptional regulating factor 1 | 0.0523096 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0522093 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0521349 |
| ATXN1 | ataxin 1 | 0.0507949 |
| OARD1 | O-acyl-ADP-ribose deacylase 1 | 0.0494863 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0474017 |
| HLA-B | major histocompatibility complex, class I, B | 0.0451692 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0450392 |
| ADAR | adenosine deaminase, RNA-specific | 0.0440731 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.0440625 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0435328 |
| ABHD2 | abhydrolase domain containing 2 | 0.0430352 |
| PCBP2 | poly(rC) binding protein 2 | 0.0422873 |
| SEPTIN9 | septin 9 | 0.041337 |
| NCKAP5 | NCK-associated protein 5 | 0.0409004 |
| RPL37 | ribosomal protein L37 | 0.040417 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0382141 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0381633 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0379651 |
| SCAPER | S-phase cyclin A-associated protein in the ER | 0.0377301 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0362287 |
| RPL26 | ribosomal protein L26 | 0.036215 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0361746 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0359967 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.0356533 |
| DSCAM | Down syndrome cell adhesion molecule | 0.035652 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0355452 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.035467 |
| TPM3 | tropomyosin 3 | 0.0350066 |
| MYO1E | myosin IE | 0.0349538 |
| CALR | calreticulin | 0.0341358 |
| BMP4 | bone morphogenetic protein 4 | 0.0335649 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0332682 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0332651 |
| RPL21 | ribosomal protein L21 | 0.0326208 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0325109 |
| RPS8 | ribosomal protein S8 | 0.0316371 |
| B2M | beta-2-microglobulin | 0.0315082 |
| CHMP4B | charged multivesicular body protein 4B | 0.0314035 |
| ETV6 | ets variant 6 | 0.0312237 |
| PADI1 | peptidyl arginine deiminase, type I | 0.0311103 |
| DSPP | dentin sialophosphoprotein | 0.0308533 |
| EGR1 | early growth response 1 | 0.0308391 |
| CD68 | CD68 molecule | 0.030817 |
| YBX3 | Y box binding protein 3 | 0.0307407 |
| STK24 | serine/threonine kinase 24 | 0.0305707 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0305427 |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like | 0.030511 |
| MKI67 | marker of proliferation Ki-67 | 0.030478 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0298468 |
| MYO10 | myosin X | 0.0296579 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0295332 |
| RPS27 | ribosomal protein S27 | 0.0294962 |
| TBC1D22A | TBC1 domain family, member 22A | 0.029308 |
| DSCAML1 | Down syndrome cell adhesion molecule like 1 | 0.0288454 |
| ATP11A | ATPase, class VI, type 11A | 0.0288257 |
| MLPH | melanophilin | 0.0284202 |
| MYO5B | myosin VB | 0.0282624 |
| FOSL2 | FOS-like antigen 2 | 0.0282299 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0281699 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.028117 |
| MT2A | metallothionein 2A | 0.0279654 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0279426 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0279373 |
| UBAC2 | UBA domain containing 2 | 0.027768 |
| ACTN4 | actinin, alpha 4 | 0.0275471 |
| RBM33 | RNA binding motif protein 33 | 0.0274178 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.026972 |
| RPL28 | ribosomal protein L28 | 0.0269269 |
| RPL23 | ribosomal protein L23 | 0.0269079 |
| RPL13A | ribosomal protein L13a | 0.0268621 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0266387 |
| TMEM59 | transmembrane protein 59 | 0.0266069 |
| TUFT1 | tuftelin 1 | 0.0262798 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.026254 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0262153 |
| RPL18 | ribosomal protein L18 | 0.0260496 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0255555 |
| SH3PXD2A | SH3 and PX domains 2A | 0.0251841 |
| IL20RA | interleukin 20 receptor, alpha | 0.0251266 |
| ABHD17C | abhydrolase domain containing 17C | 0.0250823 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0250721 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.024856 |
| GALK2 | galactokinase 2 | 0.0246338 |
| STS | steroid sulfatase (microsomal), isozyme S | 0.0244335 |
| JUP | junction plakoglobin | 0.0241957 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.121826 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.105426 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0874148 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0736855 |
| PERP | PERP, TP53 apoptosis effector | -0.0701315 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0660209 |
| JUN | jun proto-oncogene | -0.0642389 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0596229 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0585244 |
| RRBP1 | ribosome binding protein 1 | -0.0583858 |
| LYZ | lysozyme | -0.0576895 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0569274 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0543549 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0538994 |
| INTS6 | integrator complex subunit 6 | -0.0533984 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0530337 |
| FTL | ferritin, light polypeptide | -0.0528105 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0522326 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0519545 |
| ABLIM1 | actin binding LIM protein 1 | -0.0518724 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0492523 |
| COPA | coatomer protein complex, subunit alpha | -0.0492055 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0472357 |
| RAB10 | RAB10, member RAS oncogene family | -0.0463936 |
| CANX | calnexin | -0.0458957 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0458099 |
| NDRG1 | N-myc downstream regulated 1 | -0.0454499 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0449005 |
| TMSB10 | thymosin beta 10 | -0.0448304 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0447897 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0445577 |
| LCN2 | lipocalin 2 | -0.0444804 |
| H1-0 | H1.0 linker histone | -0.0435909 |
| MORF4L2 | mortality factor 4 like 2 | -0.0433706 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0429388 |
| HDLBP | high density lipoprotein binding protein | -0.0429327 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0428589 |
| MAP7 | microtubule-associated protein 7 | -0.0412882 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.040825 |
| LMO7 | LIM domain 7 | -0.0407936 |
| AGR2 | anterior gradient 2 | -0.0401099 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0381506 |
| ERBIN | erbb2 interacting protein | -0.037678 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0368814 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0365011 |
| PLIN2 | perilipin 2 | -0.0364025 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0362823 |
| RIGI | RNA sensor RIG-I | -0.0362412 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.036228 |
| HM13 | histocompatibility (minor) 13 | -0.0361835 |
| PTMA | prothymosin, alpha | -0.0358743 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0351948 |
| XRN1 | 5'-3' exoribonuclease 1 | -0.0349516 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0348808 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0342566 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0342445 |
| NEBL | nebulette | -0.0340711 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0338535 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0336803 |
| MX2 | MX dynamin-like GTPase 2 | -0.0335545 |
| ITGA6 | integrin, alpha 6 | -0.0331443 |
| GOLGB1 | golgin B1 | -0.0327343 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0326547 |
| MYO6 | myosin VI | -0.0323758 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0321535 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0320225 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0315933 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0313481 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.031266 |
| TMEM263 | transmembrane protein 263 | -0.0311151 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 | -0.0309716 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0309177 |
| ARF1 | ADP-ribosylation factor 1 | -0.0306222 |
| XAF1 | XIAP associated factor 1 | -0.0304581 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0300972 |
| GRK3 | G protein-coupled receptor kinase 3 | -0.0297515 |
| RPLP1 | ribosomal protein, large, P1 | -0.0295217 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0294814 |
| SP100 | SP100 nuclear antigen | -0.0293368 |
| GOLM2 | golgi membrane protein 2 | -0.0292703 |
| DIS3 | DIS3 exosome endoribonuclease and 3'-5' exoribonuclease | -0.0290856 |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 | -0.028608 |
| TRIM2 | tripartite motif containing 2 | -0.02856 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | -0.0284167 |
| MLEC | malectin | -0.0282135 |
| SEC24A | SEC24 family member A | -0.0278691 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0278094 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0277631 |
| SETX | senataxin | -0.0277377 |
| RAB14 | RAB14, member RAS oncogene family | -0.0276743 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0276516 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0275737 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0275195 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0273732 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | -0.02737 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0271902 |
| ARF4 | ADP-ribosylation factor 4 | -0.027132 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0270808 |
| COG6 | component of oligomeric golgi complex 6 | -0.0268508 |
| TOP1 | topoisomerase (DNA) I | -0.0268369 |
