| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Almonertinib (mesylate) perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Almonertinib (mesylate)_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FLNB | filamin B, beta | 0.357411 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.151819 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.112529 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.096367 |
| SLC35F3 | solute carrier family 35, member F3 | 0.089881 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0871426 |
| PODXL | podocalyxin-like | 0.0852259 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0810855 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.078654 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0768089 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | 0.076481 |
| FLNA | filamin A, alpha | 0.0652564 |
| CALR | calreticulin | 0.0636132 |
| EPHA2 | EPH receptor A2 | 0.0621252 |
| MEGF6 | multiple EGF-like-domains 6 | 0.0607535 |
| LAMA5 | laminin, alpha 5 | 0.0589691 |
| NAV2 | neuron navigator 2 | 0.0582266 |
| IGF2 | insulin-like growth factor 2 | 0.0581135 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.05792 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.0571937 |
| FOSL1 | FOS-like antigen 1 | 0.0552161 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0546554 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0540317 |
| ITGB4 | integrin, beta 4 | 0.0539591 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 | 0.0529419 |
| SULF1 | sulfatase 1 | 0.0526719 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0522957 |
| PLEC | plectin | 0.0516834 |
| AMOTL1 | angiomotin like 1 | 0.0503678 |
| ENO1 | enolase 1, (alpha) | 0.0496511 |
| MSN | moesin | 0.0474369 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0470756 |
| GPRC5B | G protein-coupled receptor, class C, group 5, member B | 0.0464446 |
| BLCAP | bladder cancer associated protein | 0.0461144 |
| MEF2A | myocyte enhancer factor 2A | 0.0458391 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.042523 |
| PRELID2 | PRELI domain containing 2 | 0.0421648 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0413077 |
| RPL23 | ribosomal protein L23 | 0.040867 |
| MYO10 | myosin X | 0.0398718 |
| CD9 | CD9 molecule | 0.0397838 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0396558 |
| MTSS1 | metastasis suppressor 1 | 0.039584 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0394787 |
| EFHD2 | EF-hand domain family, member D2 | 0.0391311 |
| ACTN4 | actinin, alpha 4 | 0.0390648 |
| GANAB | glucosidase, alpha; neutral AB | 0.0381167 |
| CALU | calumenin | 0.0375468 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0372809 |
| TPM3 | tropomyosin 3 | 0.0372499 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.037004 |
| COL17A1 | collagen, type XVII, alpha 1 | 0.0366874 |
| SQLE | squalene epoxidase | 0.0364467 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0362602 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0359593 |
| SH3PXD2A | SH3 and PX domains 2A | 0.0356149 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0353715 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0350921 |
| KIAA1217 | KIAA1217 | 0.0349731 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0345074 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | 0.0342144 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.033661 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0334759 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0331181 |
| RASA3 | RAS p21 protein activator 3 | 0.0330457 |
| CD47 | CD47 molecule | 0.0327893 |
| VASP | vasodilator-stimulated phosphoprotein | 0.0325919 |
| SLC45A4 | solute carrier family 45, member 4 | 0.03235 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0322233 |
| AOPEP | aminopeptidase O (putative) | 0.0319343 |
| DYNC2I1 | dynein 2 intermediate chain 1 | 0.0315302 |
| RAI1 | retinoic acid induced 1 | 0.0314617 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0314458 |
| LAMC2 | laminin, gamma 2 | 0.0312726 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0312435 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.0311247 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0310882 |
| HMGA1 | high mobility group AT-hook 1 | 0.0305586 |
| CALB1 | calbindin 1, 28kDa | 0.0304795 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0303385 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0302603 |
| RPS8 | ribosomal protein S8 | 0.0298827 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | 0.0297682 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0295604 |
| CEP250 | centrosomal protein 250kDa | 0.0295483 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0293067 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0292786 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0290247 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0287061 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0286406 |
| STK10 | serine/threonine kinase 10 | 0.0285201 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0282143 |
| PFN1 | profilin 1 | 0.0281337 |
| OGA | O-GlcNAcase | 0.027817 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0278027 |
| HLA-B | major histocompatibility complex, class I, B | 0.0274566 |
| CMIP | c-Maf inducing protein | 0.0273752 |
| B2M | beta-2-microglobulin | 0.0273556 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0272744 |
| TNS4 | tensin 4 | 0.0270774 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.139335 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.112481 |
| CLU | clusterin | -0.112188 |
| MYOF | myoferlin | -0.0686621 |
| RPS2 | ribosomal protein S2 | -0.065408 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0644321 |
| INTS6 | integrator complex subunit 6 | -0.0634305 |
| LMO7 | LIM domain 7 | -0.0619945 |
| CDK6 | cyclin-dependent kinase 6 | -0.0579935 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0566694 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0548481 |
| RPLP1 | ribosomal protein, large, P1 | -0.0536598 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0527712 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0520877 |
| TXNIP | thioredoxin interacting protein | -0.05014 |
| PDLIM5 | PDZ and LIM domain 5 | -0.049769 |
| GNAS | GNAS complex locus | -0.048858 |
| FOXP1 | forkhead box P1 | -0.0479246 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0477321 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0449168 |
| RPS6 | ribosomal protein S6 | -0.0444033 |
| JMJD1C | jumonji domain containing 1C | -0.0424938 |
| MATR3 | matrin 3 | -0.0419228 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0412928 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.041125 |
| RBM39 | RNA binding motif protein 39 | -0.0410808 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0397772 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.039325 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0389512 |
| FTL | ferritin, light polypeptide | -0.0389298 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0388942 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0388314 |
| OSMR | oncostatin M receptor | -0.0385718 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0377511 |
| STC1 | stanniocalcin 1 | -0.0375184 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0368665 |
| ASPH | aspartate beta-hydroxylase | -0.0359136 |
| DSTN | destrin (actin depolymerizing factor) | -0.0353722 |
| VCL | vinculin | -0.0351202 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0349781 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0347213 |
| RAB10 | RAB10, member RAS oncogene family | -0.0343158 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0340059 |
| CD44 | CD44 molecule (Indian blood group) | -0.0339385 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0334613 |
| IPO7 | importin 7 | -0.0325832 |
| RPS24 | ribosomal protein S24 | -0.0324989 |
| RPLP0 | ribosomal protein, large, P0 | -0.0323156 |
| RTN3 | reticulon 3 | -0.0321446 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0321343 |
| CUL4B | cullin 4B | -0.0315891 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0315829 |
| PALLD | palladin, cytoskeletal associated protein | -0.0315231 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0314924 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0310826 |
| TPX2 | TPX2, microtubule-associated | -0.0308985 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0308502 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0307033 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0303191 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0300374 |
| GOLGB1 | golgin B1 | -0.0299127 |
| CLIC4 | chloride intracellular channel 4 | -0.0296045 |
| RB1 | retinoblastoma 1 | -0.0292826 |
| BZW2 | basic leucine zipper and W2 domains 2 | -0.0289275 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0288214 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.028712 |
| ANO6 | anoctamin 6 | -0.0284583 |
| MYO9A | myosin IXA | -0.0282598 |
| JAK1 | Janus kinase 1 | -0.0280474 |
| EFCAB14 | EF-hand calcium binding domain 14 | -0.028046 |
| CPNE1 | copine I | -0.0273627 |
| POTEF | POTE ankyrin domain family, member F | -0.0271902 |
| RLF | rearranged L-myc fusion | -0.0271576 |
| DGKH | diacylglycerol kinase, eta | -0.0270053 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0269734 |
| IL6ST | interleukin 6 signal transducer | -0.0269588 |
| STK4 | serine/threonine kinase 4 | -0.0266778 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0266698 |
| TXNRD1 | thioredoxin reductase 1 | -0.0266378 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | -0.0265483 |
| RO60 | Ro60, Y RNA binding protein | -0.0261439 |
| RAB14 | RAB14, member RAS oncogene family | -0.0259757 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0258216 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | -0.0257405 |
| RPL39 | ribosomal protein L39 | -0.025732 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0256009 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0254394 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0254039 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0252874 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0252593 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0252007 |
| SP100 | SP100 nuclear antigen | -0.0250608 |
| PKM | pyruvate kinase, muscle | -0.0249241 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0248463 |
| ARF1 | ADP-ribosylation factor 1 | -0.0248159 |
| PITPNB | phosphatidylinositol transfer protein, beta | -0.0248078 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0247505 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0245124 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0242313 |
| COPA | coatomer protein complex, subunit alpha | -0.0242313 |
