| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Almonertinib (mesylate) perturbation in LoVo cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Almonertinib (mesylate)_LoVo drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.210081 |
| PRELID2 | PRELI domain containing 2 | 0.0965601 |
| RPL13A | ribosomal protein L13a | 0.096122 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0937264 |
| RPL23 | ribosomal protein L23 | 0.0887805 |
| RPS12 | ribosomal protein S12 | 0.0867317 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0763396 |
| RPL3 | ribosomal protein L3 | 0.0679244 |
| FRMD5 | FERM domain containing 5 | 0.0672581 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0655869 |
| RPS8 | ribosomal protein S8 | 0.0645927 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0609105 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0550832 |
| RPS3 | ribosomal protein S3 | 0.0542909 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0541025 |
| HSPA8 | heat shock 70kDa protein 8 | 0.052787 |
| ACTN4 | actinin, alpha 4 | 0.0516936 |
| RPL26 | ribosomal protein L26 | 0.0497286 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0467725 |
| LAMB3 | laminin, beta 3 | 0.0453349 |
| EPHA2 | EPH receptor A2 | 0.041683 |
| PCBP2 | poly(rC) binding protein 2 | 0.041115 |
| RPL5 | ribosomal protein L5 | 0.0409306 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0408167 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0395292 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0387388 |
| RPS13 | ribosomal protein S13 | 0.038053 |
| ITGB4 | integrin, beta 4 | 0.0377214 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0375686 |
| RPLP2 | ribosomal protein, large, P2 | 0.0371594 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.036839 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0355133 |
| RPL9 | ribosomal protein L9 | 0.0351896 |
| MYO5B | myosin VB | 0.0346828 |
| PTMA | prothymosin, alpha | 0.0343258 |
| RAD51B | RAD51 paralog B | 0.0340808 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0338687 |
| MED13L | mediator complex subunit 13-like | 0.0337611 |
| RPS17 | ribosomal protein S17 | 0.0335738 |
| ZNF292 | zinc finger protein 292 | 0.0334578 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0331777 |
| PLAC8 | placenta-specific 8 | 0.0323619 |
| SET | SET nuclear proto-oncogene | 0.0321577 |
| RPL6 | ribosomal protein L6 | 0.0320038 |
| RPS29 | ribosomal protein S29 | 0.0316984 |
| RPL18 | ribosomal protein L18 | 0.0305645 |
| ABHD17C | abhydrolase domain containing 17C | 0.0300348 |
| ANLN | anillin, actin binding protein | 0.030016 |
| KRT8 | keratin 8, type II | 0.029927 |
| CALU | calumenin | 0.02974 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0296065 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.0294474 |
| DENND1A | DENN/MADD domain containing 1A | 0.0294299 |
| CDK19 | cyclin-dependent kinase 19 | 0.0292409 |
| AFDN | afadin, adherens junction formation factor | 0.0290507 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0283281 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0282107 |
| RPL21 | ribosomal protein L21 | 0.0282014 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.027977 |
| FHIT | fragile histidine triad | 0.0278885 |
| RPS27A | ribosomal protein S27a | 0.0278211 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0273572 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0272875 |
| NFIA | nuclear factor I/A | 0.0271927 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | 0.0270714 |
| RPS15A | ribosomal protein S15a | 0.027003 |
| OGA | O-GlcNAcase | 0.026274 |
| CCNY | cyclin Y | 0.0261837 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.026165 |
| MUC13 | mucin 13, cell surface associated | 0.0261358 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0260403 |
| VASP | vasodilator-stimulated phosphoprotein | 0.0256291 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0256206 |
| UBC | ubiquitin C | 0.0254868 |
| HMGB2 | high mobility group box 2 | 0.0254292 |
| INSIG1 | insulin induced gene 1 | 0.0254015 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0253149 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0252655 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0252591 |
| ARRDC3 | arrestin domain containing 3 | 0.0250681 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0250668 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0245816 |
| TMCC1 | transmembrane and coiled-coil domain family 1 | 0.0244123 |
| ZFAND6 | zinc finger, AN1-type domain 6 | 0.0242628 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0242367 |
| NCKAP1 | NCK-associated protein 1 | 0.023997 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0239666 |
| KDM3B | lysine (K)-specific demethylase 3B | 0.0238411 |
| LOC105378220 | macrophage receptor MARCO-like | 0.0237449 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0235474 |
| YAP1 | Yes-associated protein 1 | 0.023328 |
| SPPL3 | signal peptide peptidase like 3 | 0.023319 |
| DNM2 | dynamin 2 | 0.0233035 |
| MCL1 | myeloid cell leukemia 1 | 0.022865 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0228068 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | 0.0227925 |
| DSPP | dentin sialophosphoprotein | 0.0227599 |
| INTS6 | integrator complex subunit 6 | 0.022596 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0224867 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | 0.0224443 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | -0.162161 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.135893 |
| RPS6 | ribosomal protein S6 | -0.119901 |
| RPLP1 | ribosomal protein, large, P1 | -0.118905 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.113943 |
| MYO1E | myosin IE | -0.0857351 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0841643 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0808846 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0728701 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0722387 |
| MYOF | myoferlin | -0.0705761 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0698257 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0673997 |
| HDLBP | high density lipoprotein binding protein | -0.0646275 |
| KRT18 | keratin 18, type I | -0.0620528 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0614903 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0604726 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0580226 |
| OXSR1 | oxidative stress responsive 1 | -0.0567429 |
| GOLGB1 | golgin B1 | -0.0534823 |
| GOLGA4 | golgin A4 | -0.0519549 |
| RIMKLB | ribosomal modification protein rimK-like family member B | -0.0518898 |
| MATR3 | matrin 3 | -0.0514626 |
| RPLP0 | ribosomal protein, large, P0 | -0.050513 |
| ITGA6 | integrin, alpha 6 | -0.0504051 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0496965 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.049362 |
| FAT1 | FAT atypical cadherin 1 | -0.0492514 |
| TJP1 | tight junction protein 1 | -0.0489409 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0484374 |
| PALLD | palladin, cytoskeletal associated protein | -0.0479149 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0468579 |
| SP100 | SP100 nuclear antigen | -0.045985 |
| CYSTM1 | cysteine-rich transmembrane module containing 1 | -0.0455961 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0455197 |
| PKP2 | plakophilin 2 | -0.0447785 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0445119 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.044164 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0440222 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0424157 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.042027 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0417229 |
| RRBP1 | ribosome binding protein 1 | -0.0416998 |
| B4GALNT3 | beta-1,4-N-acetyl-galactosaminyl transferase 3 | -0.041693 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0412255 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0411646 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0411583 |
| USP15 | ubiquitin specific peptidase 15 | -0.0408203 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.040711 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0397068 |
| MX2 | MX dynamin-like GTPase 2 | -0.0396116 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0394561 |
| ANXA2 | annexin A2 | -0.0384654 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0380423 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0379268 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0377826 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0372225 |
| ATF4 | activating transcription factor 4 | -0.0368801 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0366636 |
| AHCYL2 | adenosylhomocysteinase-like 2 | -0.0359714 |
| TRIM2 | tripartite motif containing 2 | -0.0355948 |
| PLEKHG1 | pleckstrin homology domain containing, family G (with RhoGef domain) member 1 | -0.0352034 |
| VCL | vinculin | -0.0349462 |
| INO80 | INO80 complex subunit | -0.0345436 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0342559 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0342361 |
| CANX | calnexin | -0.034169 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0341396 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0333943 |
| ACTG1 | actin gamma 1 | -0.0332773 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.033257 |
| SERINC5 | serine incorporator 5 | -0.0332549 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.033219 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0330269 |
| RPL4 | ribosomal protein L4 | -0.0328951 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -0.0328486 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0327986 |
| RPS5 | ribosomal protein S5 | -0.0324452 |
| TOP1 | topoisomerase (DNA) I | -0.0322847 |
| AGR2 | anterior gradient 2 | -0.0318936 |
| FBXO11 | F-box protein 11 | -0.031751 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0315973 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0314421 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0311559 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0309343 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0308231 |
| POTEF | POTE ankyrin domain family, member F | -0.0306502 |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 | -0.0306206 |
| FTL | ferritin, light polypeptide | -0.0303819 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0302963 |
| PKM | pyruvate kinase, muscle | -0.0299482 |
| RNF145 | ring finger protein 145 | -0.0299437 |
| BPTF | bromodomain PHD finger transcription factor | -0.0295571 |
| RPL35A | ribosomal protein L35a | -0.0293973 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0292395 |
| MYO1D | myosin ID | -0.0286065 |
| RIGI | RNA sensor RIG-I | -0.0284581 |
| PCDHB16 | protocadherin beta 16 | -0.0283906 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.0278779 |
| NCOA7 | nuclear receptor coactivator 7 | -0.027283 |
