| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Almonertinib (mesylate) perturbation in PANC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Almonertinib (mesylate)_PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.150126 |
| SEPTIN9 | septin 9 | 0.113955 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0852431 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0811866 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0723016 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0691304 |
| HMGA1 | high mobility group AT-hook 1 | 0.0632036 |
| ACTN4 | actinin, alpha 4 | 0.0615023 |
| MT2A | metallothionein 2A | 0.0602496 |
| CDK19 | cyclin-dependent kinase 19 | 0.0590021 |
| MSN | moesin | 0.0564067 |
| FOSL1 | FOS-like antigen 1 | 0.05533 |
| AFAP1 | actin filament associated protein 1 | 0.0516664 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.0480611 |
| EGFR | epidermal growth factor receptor | 0.0468393 |
| RPS12 | ribosomal protein S12 | 0.0458117 |
| RPS3 | ribosomal protein S3 | 0.0439222 |
| CMIP | c-Maf inducing protein | 0.0438268 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0435159 |
| RPLP2 | ribosomal protein, large, P2 | 0.0427377 |
| ZNF292 | zinc finger protein 292 | 0.0424884 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0422466 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0422017 |
| RPL37A | ribosomal protein L37a | 0.0394957 |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 | 0.0386547 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0380195 |
| RPS8 | ribosomal protein S8 | 0.0360711 |
| PRELID2 | PRELI domain containing 2 | 0.0355815 |
| RPL36A | ribosomal protein L36a | 0.0354584 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0354394 |
| ZNF146 | zinc finger protein 146 | 0.0351623 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0351106 |
| YEATS2 | YEATS domain containing 2 | 0.0338157 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0333318 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0332924 |
| ATXN1 | ataxin 1 | 0.0323721 |
| RPS13 | ribosomal protein S13 | 0.0313703 |
| PFN1 | profilin 1 | 0.0306852 |
| MCL1 | myeloid cell leukemia 1 | 0.0298633 |
| TPM3 | tropomyosin 3 | 0.0296478 |
| STC2 | stanniocalcin 2 | 0.0293741 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.029136 |
| RPL21 | ribosomal protein L21 | 0.0288984 |
| RPL23 | ribosomal protein L23 | 0.0281528 |
| ANGPTL4 | angiopoietin-like 4 | 0.027621 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.027489 |
| RPL13A | ribosomal protein L13a | 0.0264508 |
| PDE10A | phosphodiesterase 10A | 0.0261138 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0255688 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0254223 |
| ANLN | anillin, actin binding protein | 0.0248851 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0240922 |
| GOLT1A | golgi transport 1A | 0.0238536 |
| RPS16 | ribosomal protein S16 | 0.0235692 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.023467 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0230435 |
| RPS29 | ribosomal protein S29 | 0.0228855 |
| HM13 | histocompatibility (minor) 13 | 0.0227772 |
| PCBP2 | poly(rC) binding protein 2 | 0.0227535 |
| SP3 | Sp3 transcription factor | 0.0227285 |
| GSE1 | Gse1 coiled-coil protein | 0.0226246 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0225686 |
| RNF220 | ring finger protein 220 | 0.0225052 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | 0.0223765 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0221764 |
| RPL7 | ribosomal protein L7 | 0.0218909 |
| COL18A1 | collagen, type XVIII, alpha 1 | 0.0216429 |
| GANAB | glucosidase, alpha; neutral AB | 0.0214473 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.0214383 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0212811 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0211855 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0211807 |
| ZNF84 | zinc finger protein 84 | 0.0204432 |
| SBF2 | SET binding factor 2 | 0.0203385 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.0201786 |
| RPL5 | ribosomal protein L5 | 0.0201235 |
| HNRNPF | heterogeneous nuclear ribonucleoprotein F | 0.0200463 |
| RPS15A | ribosomal protein S15a | 0.0200329 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.019853 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0194391 |
| PXDN | peroxidasin | 0.0193539 |
| RPL9 | ribosomal protein L9 | 0.0192514 |
| TPM2 | tropomyosin 2 (beta) | 0.0191471 |
| RPL3 | ribosomal protein L3 | 0.0190573 |
| STEAP3 | STEAP family member 3, metalloreductase | 0.0188964 |
| CEP170 | centrosomal protein 170kDa | 0.0188871 |
| CEP70 | centrosomal protein 70kDa | 0.0184391 |
| GPBP1L1 | GC-rich promoter binding protein 1-like 1 | 0.0184059 |
| FLNB | filamin B, beta | 0.0183894 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0183667 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0182574 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0182434 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.0180705 |
| CTBP2 | C-terminal binding protein 2 | 0.0179559 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0179377 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0176772 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.017596 |
| AFDN | afadin, adherens junction formation factor | 0.0175093 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.017373 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0173384 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VCL | vinculin | -0.308762 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.159799 |
| VIM | vimentin | -0.147767 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.131804 |
| AHNAK | AHNAK nucleoprotein | -0.124335 |
| LOC112694756 | uncharaterized LOC112694756 | -0.10876 |
| CD44 | CD44 molecule (Indian blood group) | -0.100827 |
| ANXA2 | annexin A2 | -0.0970155 |
| TMSB10 | thymosin beta 10 | -0.0870763 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.074716 |
| RPLP1 | ribosomal protein, large, P1 | -0.0741799 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0738909 |
| RPLP0 | ribosomal protein, large, P0 | -0.0689074 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0641539 |
| FTL | ferritin, light polypeptide | -0.06391 |
| CANX | calnexin | -0.0622429 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0591704 |
| IPO7 | importin 7 | -0.0563784 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0560851 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0540433 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0527557 |
| MED29 | mediator complex subunit 29 | -0.0519178 |
| MATR3 | matrin 3 | -0.0516353 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0500535 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0496126 |
| TMEM123 | transmembrane protein 123 | -0.0495596 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0463295 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0460808 |
| MORF4L2 | mortality factor 4 like 2 | -0.0457033 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0449955 |
| APP | amyloid beta (A4) precursor protein | -0.0445437 |
| SQSTM1 | sequestosome 1 | -0.0442256 |
| NF1 | neurofibromin 1 | -0.0424709 |
| SPAG9 | sperm associated antigen 9 | -0.0423259 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0422208 |
| SFTPA2 | surfactant protein A2 | -0.0421727 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.041445 |
| OSMR | oncostatin M receptor | -0.0407527 |
| HDLBP | high density lipoprotein binding protein | -0.0396348 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.039549 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0391479 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0389234 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0380028 |
| SEPTIN7 | septin 7 | -0.0378397 |
| RPL4 | ribosomal protein L4 | -0.037817 |
| ITGAV | integrin, alpha V | -0.0378045 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0377563 |
| CARD18 | caspase recruitment domain family, member 18 | -0.0376241 |
| RPS24 | ribosomal protein S24 | -0.037612 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0370784 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0368726 |
| JMJD1C | jumonji domain containing 1C | -0.0368542 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0363141 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0362908 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0362331 |
| RAB10 | RAB10, member RAS oncogene family | -0.0359629 |
| GNAS | GNAS complex locus | -0.0358137 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0353404 |
| PSMC4 | proteasome (prosome, macropain) 26S subunit, ATPase, 4 | -0.0353208 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0350548 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0348257 |
| THOC2 | THO complex 2 | -0.0345239 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0342994 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0341298 |
| JUN | jun proto-oncogene | -0.0338376 |
| RPS5 | ribosomal protein S5 | -0.0335681 |
| RAD21 | RAD21 homolog (S. pombe) | -0.033343 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.033158 |
| RASAL2 | RAS protein activator like 2 | -0.0330291 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0326448 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0322348 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0321132 |
| ZFP36 | ZFP36 ring finger protein | -0.0319701 |
| RTN4 | reticulon 4 | -0.0318733 |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 | -0.0316686 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0316214 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0313532 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0310354 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0306677 |
| INTS6 | integrator complex subunit 6 | -0.0305231 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0301053 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0300782 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0299999 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0299815 |
| LARS1 | leucyl-tRNA synthetase 1 | -0.0296693 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | -0.02919 |
| ERBIN | erbb2 interacting protein | -0.029181 |
| CD164 | CD164 molecule, sialomucin | -0.0290252 |
| ZNF644 | zinc finger protein 644 | -0.0290077 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0289178 |
| RTN3 | reticulon 3 | -0.0287953 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0287678 |
| EGR1 | early growth response 1 | -0.0287078 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0284842 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0283722 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0283001 |
| TAOK1 | TAO kinase 1 | -0.0282412 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0281838 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0281728 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0278284 |
