| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Almonertinib (mesylate) perturbation in Panc 03.27 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Almonertinib (mesylate)_Panc 03.27 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LAMB3 | laminin, beta 3 | 0.240716 |
| MUC4 | mucin 4, cell surface associated | 0.183163 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0935572 |
| SMAD3 | SMAD family member 3 | 0.0804367 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0799182 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.079142 |
| RPS3 | ribosomal protein S3 | 0.073947 |
| CALR | calreticulin | 0.0739167 |
| HLA-B | major histocompatibility complex, class I, B | 0.0717717 |
| C3 | complement component 3 | 0.0679932 |
| KRT8 | keratin 8, type II | 0.0649281 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0603102 |
| RPL13A | ribosomal protein L13a | 0.0582668 |
| HMGA1 | high mobility group AT-hook 1 | 0.0575106 |
| RPL37A | ribosomal protein L37a | 0.0560034 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.053469 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0533974 |
| BRD2 | bromodomain containing 2 | 0.0531051 |
| KRT17 | keratin 17, type I | 0.0519994 |
| RPS8 | ribosomal protein S8 | 0.0518377 |
| RPL5 | ribosomal protein L5 | 0.0486688 |
| RPS29 | ribosomal protein S29 | 0.0457104 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0456651 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0452439 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.045074 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0449494 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0442531 |
| LAMC2 | laminin, gamma 2 | 0.043675 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0429598 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0423945 |
| ARRDC3 | arrestin domain containing 3 | 0.0420473 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | 0.041753 |
| KRT7 | keratin 7, type II | 0.0415764 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0394815 |
| VMP1 | vacuole membrane protein 1 | 0.0388094 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0376176 |
| GOLGA4 | golgin A4 | 0.0373624 |
| G0S2 | G0/G1 switch 2 | 0.0373007 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0372851 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0365683 |
| SEPTIN9 | septin 9 | 0.0362644 |
| RUNX1 | runt-related transcription factor 1 | 0.0359358 |
| RPS27A | ribosomal protein S27a | 0.0358786 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0344786 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0344741 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0344322 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0343876 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0338345 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0337893 |
| PLEC | plectin | 0.0335035 |
| RPL26 | ribosomal protein L26 | 0.0334217 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0331944 |
| ITGB4 | integrin, beta 4 | 0.0324999 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0324269 |
| UBXN7 | UBX domain protein 7 | 0.0322167 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0318437 |
| INHBA | inhibin, beta A | 0.031686 |
| GANAB | glucosidase, alpha; neutral AB | 0.0312811 |
| RPS12 | ribosomal protein S12 | 0.0312678 |
| AFDN | afadin, adherens junction formation factor | 0.0310022 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0309899 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0306544 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0304736 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0302289 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0300675 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0297994 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.0296801 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0296075 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0295853 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0294896 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0294444 |
| SLTM | SAFB-like, transcription modulator | 0.0293782 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0291069 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0290992 |
| NAV2 | neuron navigator 2 | 0.0288838 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.0288531 |
| TJP2 | tight junction protein 2 | 0.0288192 |
| VEGFA | vascular endothelial growth factor A | 0.0287478 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0285442 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0282062 |
| ACTN4 | actinin, alpha 4 | 0.0280389 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0276768 |
| HDGF | hepatoma-derived growth factor | 0.027499 |
| RPL7 | ribosomal protein L7 | 0.0273668 |
| CHMP4B | charged multivesicular body protein 4B | 0.0272129 |
| ZSWIM4 | zinc finger, SWIM-type containing 4 | 0.0271105 |
| ZC3H13 | zinc finger CCCH-type containing 13 | 0.0265687 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0263446 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0262819 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.025765 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0257578 |
| TGFB2 | transforming growth factor, beta 2 | 0.0257163 |
| RPS7 | ribosomal protein S7 | 0.0256843 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0256235 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0255282 |
| SQSTM1 | sequestosome 1 | 0.0251247 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0250063 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0249942 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0248889 |
| MYO5B | myosin VB | 0.0245489 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.204704 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.119824 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.106487 |
| TMSB10 | thymosin beta 10 | -0.0836102 |
| RPLP1 | ribosomal protein, large, P1 | -0.0777147 |
| FTL | ferritin, light polypeptide | -0.0738529 |
| ASPH | aspartate beta-hydroxylase | -0.0628776 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0562708 |
| PTMA | prothymosin, alpha | -0.0550272 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0547245 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0522957 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0518301 |
| PGK1 | phosphoglycerate kinase 1 | -0.0502562 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0493894 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0490042 |
| CD44 | CD44 molecule (Indian blood group) | -0.0483428 |
| FN1 | fibronectin 1 | -0.0474474 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0472216 |
| MX1 | MX dynamin-like GTPase 1 | -0.0471553 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.046738 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0458306 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0451866 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.044497 |
| TMEM123 | transmembrane protein 123 | -0.044276 |
| PKM | pyruvate kinase, muscle | -0.0438964 |
| VCL | vinculin | -0.0430543 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0429411 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0425784 |
| FCHSD2 | FCH and double SH3 domains 2 | -0.041325 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.040009 |
| VIM | vimentin | -0.0389005 |
| NF1 | neurofibromin 1 | -0.0387425 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0385693 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0381138 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0379013 |
| KRT19 | keratin 19, type I | -0.0378362 |
| TXNIP | thioredoxin interacting protein | -0.037497 |
| MX2 | MX dynamin-like GTPase 2 | -0.0372617 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0372232 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0369237 |
| AHNAK | AHNAK nucleoprotein | -0.0367704 |
| EFNA5 | ephrin-A5 | -0.0365608 |
| CENPF | centromere protein F, 350/400kDa | -0.0362332 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0362188 |
| NDRG1 | N-myc downstream regulated 1 | -0.0361736 |
| PERP | PERP, TP53 apoptosis effector | -0.0356699 |
| RIGI | RNA sensor RIG-I | -0.0354894 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0351221 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0347723 |
| CD2AP | CD2-associated protein | -0.0345215 |
| CDCP1 | CUB domain containing protein 1 | -0.0339364 |
| CBX3 | chromobox homolog 3 | -0.033808 |
| RPS24 | ribosomal protein S24 | -0.0335815 |
| RPS4X | ribosomal protein S4, X-linked | -0.0335641 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0334404 |
| MEF2A | myocyte enhancer factor 2A | -0.0334262 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0334048 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0331046 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.032889 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0328838 |
| LMO7 | LIM domain 7 | -0.0327759 |
| ITGA6 | integrin, alpha 6 | -0.0327452 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.031965 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0316183 |
| PRELID2 | PRELI domain containing 2 | -0.0314966 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0314279 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0312507 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.031127 |
| ATF7IP | activating transcription factor 7 interacting protein | -0.031011 |
| IFI44 | interferon-induced protein 44 | -0.0309628 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0305843 |
| IFI44L | interferon-induced protein 44-like | -0.0303333 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.030231 |
| NRP1 | neuropilin 1 | -0.030177 |
| SP100 | SP100 nuclear antigen | -0.0299467 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0295773 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.0289193 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.028887 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0288153 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.028499 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0283915 |
| LAMA4 | laminin, alpha 4 | -0.0283396 |
| SYT14 | synaptotagmin XIV | -0.0282048 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | -0.0281951 |
| TAOK1 | TAO kinase 1 | -0.0278501 |
| TUBA1B | tubulin, alpha 1b | -0.0277537 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0276602 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0275492 |
| RAB14 | RAB14, member RAS oncogene family | -0.0274689 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0273879 |
| POTEF | POTE ankyrin domain family, member F | -0.027381 |
| REEP3 | receptor accessory protein 3 | -0.0273634 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0272365 |
| NSD1 | nuclear receptor binding SET domain protein 1 | -0.0272018 |
| ANXA1 | annexin A1 | -0.0270809 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | -0.0270526 |
| BPTF | bromodomain PHD finger transcription factor | -0.0270198 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0269917 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.026352 |
| CCNL1 | cyclin L1 | -0.0262264 |
