| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Almonertinib (mesylate) perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Almonertinib (mesylate)_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.130205 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.104563 |
| FLNB | filamin B, beta | 0.102682 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0971888 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0922156 |
| ECT2 | epithelial cell transforming 2 | 0.0916186 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0794923 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0788252 |
| ZNF292 | zinc finger protein 292 | 0.077408 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0761878 |
| RPL13A | ribosomal protein L13a | 0.0743636 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | 0.0737818 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0732689 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0703975 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0698246 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0680883 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0670644 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0630111 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0628594 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0627246 |
| RPL35A | ribosomal protein L35a | 0.0624486 |
| RPL23 | ribosomal protein L23 | 0.0620409 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0605547 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0604778 |
| RPL26 | ribosomal protein L26 | 0.0600553 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | 0.0588079 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.0583989 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0550596 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0544219 |
| CD47 | CD47 molecule | 0.0541893 |
| RPS8 | ribosomal protein S8 | 0.0528273 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0518164 |
| PLXNA1 | plexin A1 | 0.0514283 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0507442 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0484494 |
| PYGB | phosphorylase, glycogen; brain | 0.0482485 |
| RPL37A | ribosomal protein L37a | 0.0466585 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.046303 |
| RPL5 | ribosomal protein L5 | 0.0458614 |
| WDR43 | WD repeat domain 43 | 0.0445239 |
| GANAB | glucosidase, alpha; neutral AB | 0.0443203 |
| LDHA | lactate dehydrogenase A | 0.044167 |
| GOLGA4 | golgin A4 | 0.0431745 |
| MSI2 | musashi RNA-binding protein 2 | 0.0431375 |
| HDAC9 | histone deacetylase 9 | 0.0430662 |
| CALR | calreticulin | 0.0416869 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0416846 |
| GLI2 | GLI family zinc finger 2 | 0.0412975 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0410933 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.040107 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0395144 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0393979 |
| PTK2 | protein tyrosine kinase 2 | 0.0387193 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 | 0.0376847 |
| VMP1 | vacuole membrane protein 1 | 0.037527 |
| NUP58 | nucleoporin 58 | 0.0374161 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0373887 |
| NAV2 | neuron navigator 2 | 0.037112 |
| RPS3 | ribosomal protein S3 | 0.0369933 |
| PCBP2 | poly(rC) binding protein 2 | 0.0369435 |
| HMGA1 | high mobility group AT-hook 1 | 0.036908 |
| RHEB | Ras homolog enriched in brain | 0.0367875 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0365965 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0364802 |
| PFN1 | profilin 1 | 0.0360217 |
| FASN | fatty acid synthase | 0.0359188 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0357776 |
| MKI67 | marker of proliferation Ki-67 | 0.0353155 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0352991 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0351768 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0351179 |
| FAT1 | FAT atypical cadherin 1 | 0.0350262 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0350083 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0349329 |
| FLNA | filamin A, alpha | 0.0348172 |
| GSE1 | Gse1 coiled-coil protein | 0.0345315 |
| FBLN2 | fibulin 2 | 0.0342077 |
| CORO1C | coronin, actin binding protein, 1C | 0.0341671 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.032951 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.0327623 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | 0.0326282 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0326249 |
| CYTH3 | cytohesin 3 | 0.0325933 |
| RPL9 | ribosomal protein L9 | 0.0325519 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0323398 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | 0.0319762 |
| CALU | calumenin | 0.0317673 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0317102 |
| ENTPD6 | ectonucleoside triphosphate diphosphohydrolase 6 (putative) | 0.0316365 |
| AMOTL2 | angiomotin like 2 | 0.0310418 |
| FAM13A | family with sequence similarity 13, member A | 0.0309501 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0309422 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0309147 |
| XPO6 | exportin 6 | 0.0304893 |
| DENND1A | DENN/MADD domain containing 1A | 0.0301427 |
| TMEM65 | transmembrane protein 65 | 0.0299946 |
| RPS13 | ribosomal protein S13 | 0.0297222 |
| CRY1 | cryptochrome circadian clock 1 | 0.0294618 |
| PRELID2 | PRELI domain containing 2 | 0.0293808 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.029127 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.148172 |
| PKM | pyruvate kinase, muscle | -0.137832 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.109032 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0906555 |
| RPS2 | ribosomal protein S2 | -0.0703819 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0654516 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0591288 |
| RPLP1 | ribosomal protein, large, P1 | -0.0480976 |
| TXNRD1 | thioredoxin reductase 1 | -0.0477837 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0470256 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0461092 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.045693 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.045256 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0452011 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0441568 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | -0.0440009 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0433165 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.040917 |
| FTL | ferritin, light polypeptide | -0.0401955 |
| CCND1 | cyclin D1 | -0.0393377 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0392624 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | -0.0388201 |
| ANXA1 | annexin A1 | -0.038089 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0380508 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0364369 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0361416 |
| GOLM2 | golgi membrane protein 2 | -0.036091 |
| TAOK1 | TAO kinase 1 | -0.0356966 |
| BMP10 | bone morphogenetic protein 10 | -0.035247 |
| RPLP0 | ribosomal protein, large, P0 | -0.0346718 |
| EXOC6B | exocyst complex component 6B | -0.0343534 |
| JMJD1C | jumonji domain containing 1C | -0.0333176 |
| DUSP6 | dual specificity phosphatase 6 | -0.0321316 |
| SLC38A2 | solute carrier family 38, member 2 | -0.032018 |
| AHNAK | AHNAK nucleoprotein | -0.0315167 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0310913 |
| TASOR2 | transcription activation suppressor family member 2 | -0.0309016 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0307543 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0306359 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0304736 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.028826 |
| ZBTB10 | zinc finger and BTB domain containing 10 | -0.0287088 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0285391 |
| GPHN | gephyrin | -0.0280716 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.028032 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0278673 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0278631 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0274921 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0269747 |
| DGKH | diacylglycerol kinase, eta | -0.0269425 |
| ZNF638 | zinc finger protein 638 | -0.0267745 |
| BBS9 | Bardet-Biedl syndrome 9 | -0.0263132 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | -0.0262799 |
| PCM1 | pericentriolar material 1 | -0.0260063 |
| OSMR | oncostatin M receptor | -0.0258401 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0256022 |
| MAN1A2 | mannosidase, alpha, class 1A, member 2 | -0.0255578 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0252202 |
| LARS1 | leucyl-tRNA synthetase 1 | -0.025009 |
| BMP2K | BMP2 inducible kinase | -0.0249599 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0244868 |
| NIN | ninein (GSK3B interacting protein) | -0.0243664 |
| BPTF | bromodomain PHD finger transcription factor | -0.0241977 |
| NBEA | neurobeachin | -0.0241218 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.0239849 |
| NF1 | neurofibromin 1 | -0.0238861 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0238294 |
| SP100 | SP100 nuclear antigen | -0.0237737 |
| DOCK3 | dedicator of cytokinesis 3 | -0.0237718 |
| RPS6 | ribosomal protein S6 | -0.0237462 |
| SNX6 | sorting nexin 6 | -0.0235857 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | -0.0234484 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0234195 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | -0.0233339 |
| CERT1 | ceramide transporter 1 | -0.0231713 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0230323 |
| MAP4 | microtubule-associated protein 4 | -0.0229292 |
| SQSTM1 | sequestosome 1 | -0.0229189 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0228803 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0226429 |
| ATP11B | ATPase, class VI, type 11B | -0.0225948 |
| MIPOL1 | mirror-image polydactyly 1 | -0.0225347 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0222747 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0220395 |
| UBXN4 | UBX domain protein 4 | -0.0220077 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | -0.0216211 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0213966 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0213748 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0213252 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.0213164 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | -0.021161 |
| MACROD2 | MACRO domain containing 2 | -0.0210901 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.0210633 |
| IL6ST | interleukin 6 signal transducer | -0.0210276 |
| SEPTIN7 | septin 7 | -0.0209672 |
| POTEF | POTE ankyrin domain family, member F | -0.0209324 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.020847 |
| PLK2 | polo-like kinase 2 | -0.0206277 |
| DENND4C | DENN/MADD domain containing 4C | -0.020597 |
| UNC5C | unc-5 homolog C (C. elegans) | -0.0205818 |
