| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Almonertinib (mesylate) perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Almonertinib (mesylate)_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0791951 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0663626 |
| STC2 | stanniocalcin 2 | 0.0651973 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0592486 |
| CALR | calreticulin | 0.0539361 |
| RPL26 | ribosomal protein L26 | 0.0502108 |
| HDGF | hepatoma-derived growth factor | 0.0494449 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0472688 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0461807 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.045403 |
| SUCO | SUN domain containing ossification factor | 0.0422469 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0420947 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0411526 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0403601 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | 0.0399049 |
| SMAD3 | SMAD family member 3 | 0.0395665 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0389835 |
| LMNA | lamin A/C | 0.0384137 |
| COG5 | component of oligomeric golgi complex 5 | 0.0380529 |
| RPS3 | ribosomal protein S3 | 0.0378045 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0370718 |
| TPR | translocated promoter region, nuclear basket protein | 0.0344174 |
| GOLGA4 | golgin A4 | 0.0343992 |
| TMF1 | TATA element modulatory factor 1 | 0.033878 |
| RPL37A | ribosomal protein L37a | 0.0328765 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0319555 |
| CTBP2 | C-terminal binding protein 2 | 0.0315346 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0313838 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0308815 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0302757 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0302317 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0296315 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | 0.0291385 |
| RPS29 | ribosomal protein S29 | 0.0289331 |
| CD63 | CD63 molecule | 0.0288478 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0286487 |
| RPS27 | ribosomal protein S27 | 0.0284465 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0284398 |
| ETV6 | ets variant 6 | 0.0279251 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0277154 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0273806 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0265404 |
| RPL18 | ribosomal protein L18 | 0.0260706 |
| RPS27A | ribosomal protein S27a | 0.0256344 |
| TNS3 | tensin 3 | 0.02517 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0251489 |
| RPL13A | ribosomal protein L13a | 0.0250222 |
| NDEL1 | nudE neurodevelopment protein 1-like 1 | 0.0248892 |
| HMGA1 | high mobility group AT-hook 1 | 0.0247187 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | 0.0246287 |
| AFDN | afadin, adherens junction formation factor | 0.0245685 |
| AEBP2 | AE binding protein 2 | 0.0245066 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0240461 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0240094 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0239975 |
| PNN | pinin, desmosome associated protein | 0.0239005 |
| TMEM165 | transmembrane protein 165 | 0.0237743 |
| VEGFA | vascular endothelial growth factor A | 0.0237461 |
| MT2A | metallothionein 2A | 0.0232511 |
| NEMF | nuclear export mediator factor | 0.0232108 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.023207 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0231157 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0229777 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | 0.0228149 |
| RPH3AL | rabphilin 3A-like (without C2 domains) | 0.022533 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0225063 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.022318 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0223121 |
| ARHGAP35 | Rho GTPase activating protein 35 | 0.0219651 |
| FAM193B | family with sequence similarity 193, member B | 0.0219195 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0217579 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0217396 |
| RAI14 | retinoic acid induced 14 | 0.0214417 |
| FAM20C | family with sequence similarity 20, member C | 0.0214168 |
| ZNF146 | zinc finger protein 146 | 0.0213751 |
| PLPP6 | phospholipid phosphatase 6 | 0.021247 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0211896 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | 0.0211758 |
| ZNF160 | zinc finger protein 160 | 0.0211711 |
| TOM1L2 | target of myb1-like 2 (chicken) | 0.0209096 |
| AKAP10 | A kinase (PRKA) anchor protein 10 | 0.0208955 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0208674 |
| SEPTIN9 | septin 9 | 0.0207638 |
| GANAB | glucosidase, alpha; neutral AB | 0.0207472 |
| TIAL1 | TIA1 cytotoxic granule-associated RNA binding protein-like 1 | 0.0206928 |
| RPL36 | ribosomal protein L36 | 0.0203188 |
| DCAF6 | DDB1 and CUL4 associated factor 6 | 0.0201948 |
| RPL23 | ribosomal protein L23 | 0.0200636 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0200314 |
| RPS8 | ribosomal protein S8 | 0.0195865 |
| LMAN2 | lectin, mannose-binding 2 | 0.0195755 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.019574 |
| DIDO1 | death inducer-obliterator 1 | 0.019519 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0192378 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0190414 |
| ZNF638 | zinc finger protein 638 | 0.0188298 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.0185506 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0184382 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0183676 |
| PDCD6 | programmed cell death 6 | 0.0183225 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.269364 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.223643 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.146435 |
| FTL | ferritin, light polypeptide | -0.12593 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.117539 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.101746 |
| FN1 | fibronectin 1 | -0.100636 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.100211 |
| ASPH | aspartate beta-hydroxylase | -0.0912152 |
| MAP1B | microtubule-associated protein 1B | -0.0900143 |
| VIM | vimentin | -0.0815512 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0792576 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.076863 |
| PLIN2 | perilipin 2 | -0.0750446 |
| RTN4 | reticulon 4 | -0.0713039 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0706562 |
| NDRG1 | N-myc downstream regulated 1 | -0.0684742 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0655657 |
| OSMR | oncostatin M receptor | -0.0654377 |
| SEPTIN7 | septin 7 | -0.063186 |
| NRP1 | neuropilin 1 | -0.0613809 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.059847 |
| VCL | vinculin | -0.0596539 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0588016 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0577026 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0567628 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0531739 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0523326 |
| IL6ST | interleukin 6 signal transducer | -0.0507355 |
| ETV1 | ets variant 1 | -0.0494079 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0487763 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0485854 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0484549 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0480521 |
| CENPF | centromere protein F, 350/400kDa | -0.0477651 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0475859 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.047361 |
| NRG1 | neuregulin 1 | -0.0468602 |
| HMGA2 | high mobility group AT-hook 2 | -0.0463653 |
| TOP1 | topoisomerase (DNA) I | -0.0454419 |
| IER3 | immediate early response 3 | -0.0445862 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0444104 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0442288 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0439876 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0434352 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0432717 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0431455 |
| CANX | calnexin | -0.0430887 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0430383 |
| RPS6 | ribosomal protein S6 | -0.0429287 |
| RPLP1 | ribosomal protein, large, P1 | -0.0424925 |
| ITGA1 | integrin, alpha 1 | -0.0422492 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0415484 |
| MATR3 | matrin 3 | -0.0400577 |
| AHR | aryl hydrocarbon receptor | -0.0397636 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.03885 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | -0.0378237 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.037761 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0373574 |
| PKM | pyruvate kinase, muscle | -0.0368578 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0367054 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0363708 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0357827 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0352948 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | -0.034626 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0335861 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.033563 |
| TXNRD1 | thioredoxin reductase 1 | -0.0332149 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0331401 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0330339 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0329346 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0328015 |
| TPM4 | tropomyosin 4 | -0.0326228 |
| GNAS | GNAS complex locus | -0.0325058 |
| PTK2 | protein tyrosine kinase 2 | -0.0319355 |
| ANXA2 | annexin A2 | -0.0315278 |
| RIOK3 | RIO kinase 3 | -0.0311571 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0311364 |
| EGR1 | early growth response 1 | -0.0311235 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0309096 |
| TSC22D2 | TSC22 domain family, member 2 | -0.030671 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0306591 |
| CBX3 | chromobox homolog 3 | -0.0306101 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | -0.0305687 |
| RPLP0 | ribosomal protein, large, P0 | -0.0304785 |
| TJP1 | tight junction protein 1 | -0.0303978 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0292857 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0291232 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0291121 |
| EZR | ezrin | -0.0288823 |
| RPL12 | ribosomal protein L12 | -0.0287656 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0286088 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0285067 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0284725 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0284177 |
| SYT1 | synaptotagmin I | -0.0280898 |
| RYBP | RING1 and YY1 binding protein | -0.0279056 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0277507 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0276059 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0275724 |
