| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Alpelisib perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Alpelisib_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.237402 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.158739 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.150399 |
| SMAD3 | SMAD family member 3 | 0.133025 |
| INTS6 | integrator complex subunit 6 | 0.109681 |
| EXT1 | exostosin glycosyltransferase 1 | 0.104779 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0863916 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0861584 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0812656 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0793541 |
| RNF213 | ring finger protein 213 | 0.0784452 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0762895 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0722521 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0714312 |
| MYO1E | myosin IE | 0.0649811 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0624147 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0604325 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0603913 |
| ANXA2 | annexin A2 | 0.058691 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0577682 |
| EFNB2 | ephrin-B2 | 0.0571683 |
| TJP1 | tight junction protein 1 | 0.0516476 |
| RUNX1 | runt-related transcription factor 1 | 0.0515288 |
| ETV6 | ets variant 6 | 0.0489186 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0488329 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0479851 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0478088 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0470257 |
| YAP1 | Yes-associated protein 1 | 0.0469719 |
| PLSCR2 | phospholipid scramblase 2 | 0.0456982 |
| FAT1 | FAT atypical cadherin 1 | 0.0443697 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0440888 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0434362 |
| LCN2 | lipocalin 2 | 0.0422937 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.041628 |
| KYNU | kynureninase | 0.0411016 |
| MYO5B | myosin VB | 0.0407507 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0377089 |
| ATXN1 | ataxin 1 | 0.0374519 |
| SEPTIN9 | septin 9 | 0.0372464 |
| MCU | mitochondrial calcium uniporter | 0.0367825 |
| HKDC1 | hexokinase domain containing 1 | 0.0358595 |
| VCL | vinculin | 0.0354877 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0352415 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0350902 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0346851 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0337797 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0336722 |
| ASPH | aspartate beta-hydroxylase | 0.0335088 |
| DST | dystonin | 0.033387 |
| LURAP1L | leucine rich adaptor protein 1-like | 0.0332411 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0327471 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | 0.0324313 |
| DPP4 | dipeptidyl-peptidase 4 | 0.0324307 |
| STK24 | serine/threonine kinase 24 | 0.0323141 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.031816 |
| SIK3 | SIK family kinase 3 | 0.0314587 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0305005 |
| VMP1 | vacuole membrane protein 1 | 0.0303656 |
| TRIM2 | tripartite motif containing 2 | 0.0298154 |
| UTRN | utrophin | 0.0292299 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0288951 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0286245 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0284983 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0280217 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0277956 |
| APP | amyloid beta (A4) precursor protein | 0.0277685 |
| TOX3 | TOX high mobility group box family member 3 | 0.0274103 |
| NEBL | nebulette | 0.0271811 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0270373 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0269979 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0269175 |
| CTBP2 | C-terminal binding protein 2 | 0.026739 |
| ATP11A | ATPase, class VI, type 11A | 0.0263493 |
| CANX | calnexin | 0.0261751 |
| TMEM65 | transmembrane protein 65 | 0.0257209 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0250564 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0250309 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0249881 |
| MSI2 | musashi RNA-binding protein 2 | 0.024953 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0247238 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0244952 |
| MAP7 | microtubule-associated protein 7 | 0.0240205 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0240117 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0238414 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0237644 |
| TMC5 | transmembrane channel-like 5 | 0.0236557 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0236506 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0236037 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0235863 |
| PDZD8 | PDZ domain containing 8 | 0.0234826 |
| WWOX | WW domain containing oxidoreductase | 0.0231639 |
| FNIP2 | folliculin interacting protein 2 | 0.0231125 |
| AFAP1L2 | actin filament associated protein 1-like 2 | 0.0230808 |
| SPAG9 | sperm associated antigen 9 | 0.0228827 |
| SQSTM1 | sequestosome 1 | 0.0224208 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0222726 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0221174 |
| SERINC5 | serine incorporator 5 | 0.0220429 |
| NABP1 | nucleic acid binding protein 1 | 0.0220278 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.104284 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.101917 |
| PTMA | prothymosin, alpha | -0.0971958 |
| LYZ | lysozyme | -0.0882834 |
| NDRG1 | N-myc downstream regulated 1 | -0.0705818 |
| NPSR1 | neuropeptide S receptor 1 | -0.0696583 |
| B2M | beta-2-microglobulin | -0.0686828 |
| HLA-B | major histocompatibility complex, class I, B | -0.0568725 |
| EGR1 | early growth response 1 | -0.0556176 |
| TXNIP | thioredoxin interacting protein | -0.0502571 |
| RPL35A | ribosomal protein L35a | -0.0462273 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0442776 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0437854 |
| TMSB10 | thymosin beta 10 | -0.0437507 |
| FTL | ferritin, light polypeptide | -0.040369 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0388006 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0378066 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0364484 |
| SSH2 | slingshot protein phosphatase 2 | -0.0347483 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0330954 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0314816 |
| S100A6 | S100 calcium binding protein A6 | -0.0309055 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0293206 |
| JUN | jun proto-oncogene | -0.0290106 |
| RPL34 | ribosomal protein L34 | -0.0279731 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0269124 |
| ITGA6 | integrin, alpha 6 | -0.0265114 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0262887 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0262721 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0256548 |
| MUC20 | mucin 20, cell surface associated | -0.0255232 |
| RPS6 | ribosomal protein S6 | -0.0254509 |
| XAF1 | XIAP associated factor 1 | -0.0252936 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0250649 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0249991 |
| RPL7L1 | ribosomal protein L7-like 1 | -0.0249444 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0246535 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0245905 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0243467 |
| TAOK3 | TAO kinase 3 | -0.0240401 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0236924 |
| CTSD | cathepsin D | -0.0236315 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0234952 |
| RRBP1 | ribosome binding protein 1 | -0.0234592 |
| CSTB | cystatin B (stefin B) | -0.0233793 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0228162 |
| WDR45B | WD repeat domain 45B | -0.0223578 |
| GNAS | GNAS complex locus | -0.0222881 |
| RNF149 | ring finger protein 149 | -0.0221344 |
| MPHOSPH8 | M-phase phosphoprotein 8 | -0.0215563 |
| RPS19 | ribosomal protein S19 | -0.0213921 |
| HMGB1 | high mobility group box 1 | -0.0213309 |
| ATF4 | activating transcription factor 4 | -0.0208032 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0206129 |
| DIAPH3 | diaphanous-related formin 3 | -0.0202978 |
| CST3 | cystatin C | -0.0199373 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0198668 |
| PTEN | phosphatase and tensin homolog | -0.0198584 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0198109 |
| RPL37A | ribosomal protein L37a | -0.0196572 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0196451 |
| RPS24 | ribosomal protein S24 | -0.0195676 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0193924 |
| APOL1 | apolipoprotein L, 1 | -0.019358 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0191635 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.0190216 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0189197 |
| HLA-E | major histocompatibility complex, class I, E | -0.0188671 |
| ANXA4 | annexin A4 | -0.018857 |
| RBM25 | RNA binding motif protein 25 | -0.0187402 |
| LIMA1 | LIM domain and actin binding 1 | -0.0185975 |
| ACTG1 | actin gamma 1 | -0.0185322 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0184748 |
| ESRP1 | epithelial splicing regulatory protein 1 | -0.0182953 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0181649 |
| EPCAM | epithelial cell adhesion molecule | -0.0181135 |
| MT2A | metallothionein 2A | -0.0181072 |
| PMP22 | peripheral myelin protein 22 | -0.0178378 |
| TMPRSS4 | transmembrane protease, serine 4 | -0.0178321 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0178007 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0176452 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0176351 |
| TFRC | transferrin receptor | -0.0175392 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.017463 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0173769 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0171411 |
| CCNL1 | cyclin L1 | -0.0170259 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0169547 |
| BRCA2 | breast cancer 2, early onset | -0.0169326 |
| TFF3 | trefoil factor 3 (intestinal) | -0.0169288 |
| PRSS3 | protease, serine, 3 | -0.0169156 |
| PGK1 | phosphoglycerate kinase 1 | -0.0168443 |
| CSTPP1 | centriolar satellite-associated tubulin polyglutamylase complex regulator 1 | -0.0167233 |
| ATP10B | ATPase, class V, type 10B | -0.0167069 |
| PTGR1 | prostaglandin reductase 1 | -0.0166931 |
| RPL23 | ribosomal protein L23 | -0.0166443 |
| CDC42SE2 | CDC42 small effector 2 | -0.0165648 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.0165421 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0165205 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0164231 |
