Symbol |
Name |
Standardized Value |
PRIM2
|
primase, DNA, polypeptide 2 (58kDa)
|
2.462
|
CTC1
|
CTS telomere maintenance complex component 1
|
2.414
|
MCM10
|
minichromosome maintenance complex component 10
|
2.376
|
WDHD1
|
WD repeat and HMG-box DNA binding protein 1
|
2.346
|
PRIM1
|
primase, DNA, polypeptide 1 (49kDa)
|
2.272
|
TEN1
|
TEN1 CST complex subunit
|
2.27
|
STN1
|
STN1 subunit of CST complex
|
2.22
|
CDC45
|
cell division cycle 45
|
2.179
|
POLA1
|
polymerase (DNA directed), alpha 1, catalytic subunit
|
2.155
|
POLR1A
|
polymerase (RNA) I polypeptide A, 194kDa
|
2.123
|
POLA2
|
polymerase (DNA directed), alpha 2, accessory subunit
|
2.064
|
PRIMPOL
|
primase and polymerase (DNA-directed)
|
2.035
|
PCNA
|
proliferating cell nuclear antigen
|
1.999
|
POLR1B
|
polymerase (RNA) I polypeptide B, 128kDa
|
1.981
|
RPA3
|
replication protein A3, 14kDa
|
1.967
|
POLE2
|
polymerase (DNA directed), epsilon 2, accessory subunit
|
1.908
|
DNA2
|
DNA replication helicase/nuclease 2
|
1.877
|
TIPIN
|
TIMELESS interacting protein
|
1.849
|
LRIG1
|
leucine-rich repeats and immunoglobulin-like domains 1
|
1.841
|
RTEL1
|
regulator of telomere elongation helicase 1
|
1.836
|
MCM7
|
minichromosome maintenance complex component 7
|
1.8
|
GINS4
|
GINS complex subunit 4 (Sld5 homolog)
|
1.787
|
FEN1
|
flap structure-specific endonuclease 1
|
1.785
|
PIF1
|
PIF1 5'-to-3' DNA helicase
|
1.739
|
MCM5
|
minichromosome maintenance complex component 5
|
1.732
|
CDC6
|
cell division cycle 6
|
1.731
|
HELB
|
helicase (DNA) B
|
1.674
|
ANXA6
|
annexin A6
|
1.655
|
DBF4
|
DBF4 zinc finger
|
1.654
|
CDT1
|
chromatin licensing and DNA replication factor 1
|
1.65
|
MCM3
|
minichromosome maintenance complex component 3
|
1.626
|
RAD52
|
RAD52 homolog (S. cerevisiae)
|
1.612
|
POLE4
|
polymerase (DNA-directed), epsilon 4, accessory subunit
|
1.608
|
MCM4
|
minichromosome maintenance complex component 4
|
1.567
|
MCM6
|
minichromosome maintenance complex component 6
|
1.538
|
POLE3
|
polymerase (DNA directed), epsilon 3, accessory subunit
|
1.537
|
POT1
|
protection of telomeres 1
|
1.536
|
LRIF1
|
ligand dependent nuclear receptor interacting factor 1
|
1.523
|
GINS3
|
GINS complex subunit 3 (Psf3 homolog)
|
1.517
|
TOPBP1
|
topoisomerase (DNA) II binding protein 1
|
1.493
|
ACD
|
adrenocortical dysplasia homolog (mouse)
|
1.479
|
TERF1
|
telomeric repeat binding factor (NIMA-interacting) 1
|
1.475
|
EXO1
|
exonuclease 1
|
1.47
|
TINF2
|
TERF1 (TRF1)-interacting nuclear factor 2
|
1.447
|
POLE
|
polymerase (DNA directed), epsilon, catalytic subunit
|
1.434
|
ATAD5
|
ATPase family, AAA domain containing 5
|
1.419
|
SSBP1
|
single-stranded DNA binding protein 1, mitochondrial
|
1.419
|
TP53BP1
|
tumor protein p53 binding protein 1
|
1.405
|
POLD1
|
polymerase (DNA directed), delta 1, catalytic subunit
|
1.404
|
IZUMO1
|
izumo sperm-egg fusion 1
|
1.396
|
CLSPN
|
claspin
|
1.39
|
POLL
|
polymerase (DNA directed), lambda
|
1.367
|
CCNA1
|
cyclin A1
|
1.365
|
CCNA2
|
cyclin A2
|
1.365
|
TENT4A
|
terminal nucleotidyltransferase 4A
|
1.364
|
TOP1MT
|
topoisomerase (DNA) I, mitochondrial
|
1.363
|
WRN
|
Werner syndrome, RecQ helicase-like
|
1.347
|
RAD51
|
RAD51 recombinase
|
1.341
|
TIMELESS
|
timeless circadian clock
|
1.335
|
ERCC2
|
excision repair cross-complementation group 2
|
1.327
|
REV3L
|
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
|
1.286
|
RAD50
|
RAD50 homolog (S. cerevisiae)
|
1.286
|
POLD3
|
polymerase (DNA-directed), delta 3, accessory subunit
|
1.267
|
CDK2
|
cyclin-dependent kinase 2
|
1.265
|
MTBP
|
MDM2 binding protein
|
1.242
|
CHEK1
|
checkpoint kinase 1
|
1.236
|
CCDC93
|
coiled-coil domain containing 93
|
1.231
|
ATM
|
ATM serine/threonine kinase
|
1.22
|
TOP1
|
topoisomerase (DNA) I
|
1.203
|
GINS1
|
GINS complex subunit 1 (Psf1 homolog)
|
1.196
|
TICRR
|
TOPBP1-interacting checkpoint and replication regulator
|
1.19
|
BRIP1
|
BRCA1 interacting protein C-terminal helicase 1
|
1.189
|
RFC3
|
replication factor C (activator 1) 3, 38kDa
|
1.163
|
CIAPIN1
|
cytokine induced apoptosis inhibitor 1
|
1.161
|
ORC5
|
origin recognition complex, subunit 5
|
1.146
|
BRCA1
|
breast cancer 1, early onset
|
1.134
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
1.123
|
SERPINA2
|
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 2 (gene/pseudogene)
|
1.117
|
CCDC22
|
coiled-coil domain containing 22
|
1.111
|
NTHL1
|
nth endonuclease III-like 1 (E. coli)
|
1.101
|
CHEK2
|
checkpoint kinase 2
|
1.098
|
MAL2
|
mal, T-cell differentiation protein 2 (gene/pseudogene)
|
1.094
|
DDX11
|
DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11
|
1.092
|
TP53
|
tumor protein p53
|
1.089
|
BUB1
|
BUB1 mitotic checkpoint serine/threonine kinase
|
1.085
|
RFC4
|
replication factor C (activator 1) 4, 37kDa
|
1.082
|
DONSON
|
downstream neighbor of SON
|
1.075
|
SEM1
|
SEM1 26S proteasome subunit
|
1.066
|
RECQL4
|
RecQ protein-like 4
|
1.062
|
SCAI
|
suppressor of cancer cell invasion
|
1.06
|
PDK3
|
pyruvate dehydrogenase kinase, isozyme 3
|
1.06
|
BRCA2
|
breast cancer 2, early onset
|
1.059
|
DCLRE1B
|
DNA cross-link repair 1B
|
1.056
|
MAD2L2
|
MAD2 mitotic arrest deficient-like 2 (yeast)
|
1.043
|
SHLD3
|
shieldin complex subunit 3
|
1.038
|
CDCA5
|
cell division cycle associated 5
|
1.027
|
REV1
|
REV1, polymerase (DNA directed)
|
1.022
|
POLH
|
polymerase (DNA directed), eta
|
1.017
|
CCDC169-SOHLH2
|
CCDC169-SOHLH2 readthrough
|
0.997
|
RAD18
|
RAD18 E3 ubiquitin protein ligase
|
0.992
|
CDC7
|
cell division cycle 7
|
0.979
|
PDHX
|
pyruvate dehydrogenase complex, component X
|
0.967
|
RECQL
|
RecQ helicase-like
|
0.961
|
ASTE1
|
asteroid homolog 1 (Drosophila)
|
0.96
|
POLDIP3
|
polymerase (DNA-directed), delta interacting protein 3
|
0.957
|
MMS19
|
MMS19 nucleotide excision repair homolog (S. cerevisiae)
|
0.946
|
DHX36
|
DEAH (Asp-Glu-Ala-His) box polypeptide 36
|
0.946
|
SEPTIN7
|
septin 7
|
0.944
|
MSMB
|
microseminoprotein, beta-
|
0.937
|
XPA
|
xeroderma pigmentosum, complementation group A
|
0.933
|
POLD2
|
polymerase (DNA directed), delta 2, accessory subunit
|
0.929
|
MRC1
|
mannose receptor, C type 1
|
0.909
|
CIAO2A
|
cytosolic iron-sulfur assembly component 2A
|
0.905
|
ETS1
|
v-ets avian erythroblastosis virus E26 oncogene homolog 1
|
0.901
|
MUS81
|
MUS81 structure-specific endonuclease subunit
|
0.892
|
ERCC1
|
excision repair cross-complementation group 1
|
0.889
|
CRCT1
|
cysteine-rich C-terminal 1
|
0.884
|
CLCC1
|
chloride channel CLIC-like 1
|
0.867
|
SDE2
|
SDE2 telomere maintenance homolog (S. pombe)
|
0.858
|
SLX4
|
SLX4 structure-specific endonuclease subunit
|
0.856
|
TCHP
|
trichoplein, keratin filament binding
|
0.855
|
RAD54B
|
RAD54 homolog B (S. cerevisiae)
|
0.85
|
TPTE2
|
transmembrane phosphoinositide 3-phosphatase and tensin homolog 2
|
0.843
|
CNFN
|
cornifelin
|
0.84
|
FANCM
|
Fanconi anemia, complementation group M
|
0.832
|
PAICS
|
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
|
0.831
|
NSMCE2
|
non-SMC element 2, MMS21 homolog (S. cerevisiae)
|
0.83
|
SLX1A
|
SLX1 structure-specific endonuclease subunit homolog A (S. cerevisiae)
|
0.821
|
TTK
|
TTK protein kinase
|
0.82
|
ORC6
|
origin recognition complex, subunit 6
|
0.805
|
PXMP4
|
peroxisomal membrane protein 4, 24kDa
|
0.801
|
RBBP8
|
retinoblastoma binding protein 8
|
0.798
|
SHF
|
Src homology 2 domain containing F
|
0.794
|
GANAB
|
glucosidase, alpha; neutral AB
|
0.792
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
0.789
|
SMC3
|
structural maintenance of chromosomes 3
|
0.788
|
CDK1
|
cyclin-dependent kinase 1
|
0.782
|
ABHD11
|
abhydrolase domain containing 11
|
0.781
|
NEK2
|
NIMA-related kinase 2
|
0.781
|
RNF168
|
ring finger protein 168, E3 ubiquitin protein ligase
|
0.781
|
CNTN2
|
contactin 2 (axonal)
|
0.776
|
ZRANB3
|
zinc finger, RAN-binding domain containing 3
|
0.774
|
GEN1
|
GEN1 Holliday junction 5' flap endonuclease
|
0.772
|
UNG
|
uracil-DNA glycosylase
|
0.769
|
TERT
|
telomerase reverse transcriptase
|
0.768
|
TERB2
|
telomere repeat binding bouquet formation protein 2
|
0.758
|
SDSL
|
serine dehydratase-like
|
0.749
|
UBR1
|
ubiquitin protein ligase E3 component n-recognin 1
|
0.739
|
WEE1
|
WEE1 G2 checkpoint kinase
|
0.737
|
USP51
|
ubiquitin specific peptidase 51
|
0.731
|
ANKHD1
|
ankyrin repeat and KH domain containing 1
|
0.73
|
ANKRD17
|
ankyrin repeat domain 17
|
0.728
|
POLM
|
polymerase (DNA directed), mu
|
0.716
|
PAXIP1
|
PAX interacting (with transcription-activation domain) protein 1
|
0.711
|
HLTF
|
helicase-like transcription factor
|
0.71
|
MUTYH
|
mutY homolog
|
0.707
|
SULT1E1
|
sulfotransferase family 1E, estrogen-preferring, member 1
|
0.706
|
TMEM107
|
transmembrane protein 107
|
0.705
|
SMARCAL1
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
|
0.703
|
TOMM70
|
translocase of outer mitochondrial membrane 70
|
0.698
|
CIAO2B
|
cytosolic iron-sulfur assembly component 2B
|
0.691
|
XRCC3
|
X-ray repair complementing defective repair in Chinese hamster cells 3
|
0.689
|
MRGBP
|
MRG/MORF4L binding protein
|
0.687
|
MAJIN
|
membrane anchored junction protein
|
0.682
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
0.68
|
MAD2L1
|
MAD2 mitotic arrest deficient-like 1 (yeast)
|
0.674
|
SHLD2
|
shieldin complex subunit 2
|
0.674
|
POLG2
|
polymerase (DNA directed), gamma 2, accessory subunit
|
0.669
|
SRF
|
serum response factor (c-fos serum response element-binding transcription factor)
|
0.668
|
SH2D3A
|
SH2 domain containing 3A
|
0.66
|
EPC1
|
enhancer of polycomb homolog 1 (Drosophila)
|
0.658
|
USP26
|
ubiquitin specific peptidase 26
|
0.657
|
WAPL
|
WAPL cohesin release factor
|
0.653
|
PWP2
|
PWP2 periodic tryptophan protein homolog (yeast)
|
0.652
|
CCNB1IP1
|
cyclin B1 interacting protein 1, E3 ubiquitin protein ligase
|
0.649
|
AGXT2
|
alanine--glyoxylate aminotransferase 2
|
0.648
|
MED29
|
mediator complex subunit 29
|
0.646
|
MYB
|
v-myb avian myeloblastosis viral oncogene homolog
|
0.638
|
PGA4
|
pepsinogen 4, group I (pepsinogen A)
|
0.637
|
ERCC6
|
excision repair cross-complementation group 6
|
0.636
|
DNAH8
|
dynein, axonemal, heavy chain 8
|
0.635
|
EME1
|
essential meiotic structure-specific endonuclease 1
|
0.633
|
PPP2R5B
|
protein phosphatase 2, regulatory subunit B', beta
|
0.629
|
CIAO1
|
cytosolic iron-sulfur assembly component 1
|
0.627
|
FHIT
|
fragile histidine triad
|
0.627
|
WWOX
|
WW domain containing oxidoreductase
|
0.627
|
FXN
|
frataxin
|
0.625
|
TERB1
|
telomere repeat binding bouquet formation protein 1
|
0.625
|
PGA3
|
pepsinogen 3, group I (pepsinogen A)
|
0.623
|
WRNIP1
|
Werner helicase interacting protein 1
|
0.615
|
USP1
|
ubiquitin specific peptidase 1
|
0.615
|
SOX12
|
SRY (sex determining region Y)-box 12
|
0.607
|
EXOG
|
endo/exonuclease (5'-3'), endonuclease G-like
|
0.607
|
STARD7
|
StAR-related lipid transfer (START) domain containing 7
|
0.606
|
XRCC6
|
X-ray repair complementing defective repair in Chinese hamster cells 6
|
0.606
|
RNF4
|
ring finger protein 4
|
0.605
|
CDC27
|
cell division cycle 27
|
0.604
|
CCNE1
|
cyclin E1
|
0.602
|
SBDS
|
Shwachman-Bodian-Diamond syndrome
|
0.592
|
MCM9
|
minichromosome maintenance complex component 9
|
0.589
|
SHLD1
|
shieldin complex subunit 1
|
0.586
|
PARP1
|
poly (ADP-ribose) polymerase 1
|
0.58
|
ANAPC1
|
anaphase promoting complex subunit 1
|
0.58
|
FBXO4
|
F-box protein 4
|
0.58
|
NUP43
|
nucleoporin 43kDa
|
0.577
|
RAD17
|
RAD17 homolog (S. pombe)
|
0.572
|
ZFR
|
zinc finger RNA binding protein
|
0.571
|
ATRIP
|
ATR interacting protein
|
0.57
|
CCNY
|
cyclin Y
|
0.569
|
NUBP2
|
nucleotide binding protein 2
|
0.569
|
NUP58
|
nucleoporin 58
|
0.568
|
USP46
|
ubiquitin specific peptidase 46
|
0.568
|
PPP4R3B
|
protein phosphatase 4 regulatory subunit 3B
|
0.566
|
CLYBL
|
citrate lyase beta like
|
0.564
|
FSBP
|
fibrinogen silencer binding protein
|
0.563
|
SOHLH1
|
spermatogenesis and oogenesis specific basic helix-loop-helix 1
|
0.559
|
NETO2
|
neuropilin (NRP) and tolloid (TLL)-like 2
|
0.552
|
USP12
|
ubiquitin specific peptidase 12
|
0.547
|
GTSE1
|
G-2 and S-phase expressed 1
|
0.547
|
ERCC3
|
excision repair cross-complementation group 3
|
0.546
|
BABAM1
|
BRISC and BRCA1 A complex member 1
|
0.546
|
MKRN1
|
makorin ring finger protein 1
|
0.545
|
MOAP1
|
modulator of apoptosis 1
|
0.544
|
ZBED1
|
zinc finger, BED-type containing 1
|
0.544
|
MEAF6
|
MYST/Esa1-associated factor 6
|
0.544
|
KANSL1
|
KAT8 regulatory NSL complex subunit 1
|
0.543
|
AMT
|
aminomethyltransferase
|
0.542
|
NFYA
|
nuclear transcription factor Y, alpha
|
0.541
|
NTPCR
|
nucleoside-triphosphatase, cancer-related
|
0.539
|
H2AC20
|
H2A clustered histone 20
|
0.538
|
H2AC19
|
H2A clustered histone 19
|
0.537
|
RLIM
|
ring finger protein, LIM domain interacting
|
0.535
|
AOC2
|
amine oxidase, copper containing 2 (retina-specific)
|
0.535
|
TM7SF2
|
transmembrane 7 superfamily member 2
|
0.533
|
FBXO3
|
F-box protein 3
|
0.525
|
NUP37
|
nucleoporin 37kDa
|
0.524
|
ORC3
|
origin recognition complex, subunit 3
|
0.523
|
PPP2CB
|
protein phosphatase 2, catalytic subunit, beta isozyme
|
0.522
|
ZNF410
|
zinc finger protein 410
|
0.52
|
FBXO8
|
F-box protein 8
|
0.518
|
SPRTN
|
SprT-like N-terminal domain
|
0.518
|
DERL3
|
derlin 3
|
0.514
|
ESCO1
|
establishment of sister chromatid cohesion N-acetyltransferase 1
|
0.51
|
RFC5
|
replication factor C (activator 1) 5, 36.5kDa
|
0.509
|
RNF8
|
ring finger protein 8, E3 ubiquitin protein ligase
|
0.507
|
MSH3
|
mutS homolog 3
|
0.504
|
MAPK1
|
mitogen-activated protein kinase 1
|
0.502
|
GMNN
|
geminin, DNA replication inhibitor
|
0.502
|