| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Altretamine perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Altretamine_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0662218 |
| MMP12 | matrix metallopeptidase 12 | 0.0606612 |
| CCNL1 | cyclin L1 | 0.052489 |
| PCBP2 | poly(rC) binding protein 2 | 0.0439817 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0428409 |
| JMJD1C | jumonji domain containing 1C | 0.0384164 |
| YAP1 | Yes-associated protein 1 | 0.0380779 |
| TPM3 | tropomyosin 3 | 0.0359539 |
| VMP1 | vacuole membrane protein 1 | 0.0342241 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.0337239 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0308379 |
| PDGFC | platelet derived growth factor C | 0.0304093 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0269119 |
| MED13L | mediator complex subunit 13-like | 0.0258728 |
| BCHE | butyrylcholinesterase | 0.0254087 |
| XPO1 | exportin 1 | 0.0252142 |
| NUP58 | nucleoporin 58 | 0.0249386 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0248463 |
| NHSL1 | NHS-like 1 | 0.0245823 |
| ASPH | aspartate beta-hydroxylase | 0.0243528 |
| NECTIN3 | nectin cell adhesion molecule 3 | 0.023049 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0229951 |
| CDK17 | cyclin-dependent kinase 17 | 0.0223091 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0221082 |
| MGAT4C | MGAT4 family, member C | 0.0216842 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0216743 |
| EPHA6 | EPH receptor A6 | 0.0215214 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.0213984 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | 0.0210191 |
| YEATS2 | YEATS domain containing 2 | 0.0210041 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0209008 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0208972 |
| FNIP1 | folliculin interacting protein 1 | 0.0205428 |
| TBK1 | TANK-binding kinase 1 | 0.0204014 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0199817 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0190272 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0189616 |
| RRM2 | ribonucleotide reductase M2 | 0.0189612 |
| USP34 | ubiquitin specific peptidase 34 | 0.0187376 |
| WDR43 | WD repeat domain 43 | 0.018324 |
| ANXA1 | annexin A1 | 0.0183032 |
| KLHL24 | kelch-like family member 24 | 0.0181514 |
| NBAS | neuroblastoma amplified sequence | 0.0181207 |
| USP14 | ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) | 0.0178348 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0178161 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0177991 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0177016 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0176392 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | 0.0175886 |
| GASK1B | golgi associated kinase 1B | 0.0171673 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0171654 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0171144 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0170666 |
| ZNF292 | zinc finger protein 292 | 0.0168723 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0165853 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0163749 |
| NEBL | nebulette | 0.0163394 |
| CLTC | clathrin, heavy chain (Hc) | 0.0163347 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.016093 |
| PRR16 | proline rich 16 | 0.0159289 |
| TFG | TRK-fused gene | 0.0159249 |
| PTK2 | protein tyrosine kinase 2 | 0.0158824 |
| CLDND1 | claudin domain containing 1 | 0.0158171 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0157863 |
| RPL3 | ribosomal protein L3 | 0.0156552 |
| MEMO1 | mediator of cell motility 1 | 0.0155884 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0154987 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.015026 |
| ARRDC3 | arrestin domain containing 3 | 0.0148966 |
| RSF1 | remodeling and spacing factor 1 | 0.014864 |
| FHIT | fragile histidine triad | 0.0148491 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.0147101 |
| PRELID2 | PRELI domain containing 2 | 0.0146611 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0145963 |
| SESN2 | sestrin 2 | 0.0145898 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0145462 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.014493 |
| MTAP | methylthioadenosine phosphorylase | 0.0144485 |
| DSPP | dentin sialophosphoprotein | 0.0142848 |
| CEP192 | centrosomal protein 192kDa | 0.0142316 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0142114 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0139904 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0139534 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0139398 |
| NEK7 | NIMA-related kinase 7 | 0.0138602 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0137286 |
| RCOR1 | REST corepressor 1 | 0.0137162 |
| HSPA4 | heat shock 70kDa protein 4 | 0.0136956 |
| WDPCP | WD repeat containing planar cell polarity effector | 0.0136907 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0136362 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0134585 |
| PNN | pinin, desmosome associated protein | 0.0134384 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0134173 |
| MTCL1 | microtubule crosslinking factor 1 | 0.0133933 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.013354 |
| PCM1 | pericentriolar material 1 | 0.0131121 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | 0.0130609 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0130514 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0128772 |
| IPO7 | importin 7 | 0.0128685 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.279709 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.195344 |
| TMSB10 | thymosin beta 10 | -0.192909 |
| AREG | amphiregulin | -0.135364 |
| FTL | ferritin, light polypeptide | -0.101279 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0715482 |
| PTMA | prothymosin, alpha | -0.0691006 |
| RPL35A | ribosomal protein L35a | -0.064304 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0622912 |
| RPLP1 | ribosomal protein, large, P1 | -0.058555 |
| RPL23 | ribosomal protein L23 | -0.0566868 |
| RPS8 | ribosomal protein S8 | -0.0554238 |
| PCDH7 | protocadherin 7 | -0.0541747 |
| RPL19 | ribosomal protein L19 | -0.0501775 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | -0.0493629 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.0491335 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0489147 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0488492 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0477173 |
| RPS3 | ribosomal protein S3 | -0.0466366 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0463153 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0449894 |
| RPS6 | ribosomal protein S6 | -0.0429496 |
| RPS27A | ribosomal protein S27a | -0.0427294 |
| RPL26 | ribosomal protein L26 | -0.0421439 |
| RPL34 | ribosomal protein L34 | -0.0420801 |
| RPS19 | ribosomal protein S19 | -0.0416589 |
| AHNAK | AHNAK nucleoprotein | -0.0415222 |
| CCND1 | cyclin D1 | -0.0412959 |
| RPL12 | ribosomal protein L12 | -0.0407099 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0398376 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0394496 |
| ACTG1 | actin gamma 1 | -0.0390861 |
| RPS24 | ribosomal protein S24 | -0.0379918 |
| RPLP2 | ribosomal protein, large, P2 | -0.0378358 |
| RPL8 | ribosomal protein L8 | -0.0375434 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0374666 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0366131 |
| TPI1 | triosephosphate isomerase 1 | -0.0355001 |
| RPL31 | ribosomal protein L31 | -0.0347417 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0346419 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0343774 |
| RPL36 | ribosomal protein L36 | -0.0343195 |
| RACK1 | receptor for activated C kinase 1 | -0.0337611 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0336505 |
| RPL11 | ribosomal protein L11 | -0.0332228 |
| RPS21 | ribosomal protein S21 | -0.0315411 |
| RPL28 | ribosomal protein L28 | -0.0315155 |
| RPS16 | ribosomal protein S16 | -0.0314947 |
| EDN1 | endothelin 1 | -0.0307176 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0302724 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0302237 |
| GNAS | GNAS complex locus | -0.0301785 |
| RPL37 | ribosomal protein L37 | -0.0298967 |
| RPS12 | ribosomal protein S12 | -0.0292026 |
| RPL37A | ribosomal protein L37a | -0.0290094 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0287089 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0287065 |
| RPL38 | ribosomal protein L38 | -0.0286763 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0280963 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0276234 |
| RPS14 | ribosomal protein S14 | -0.0275954 |
| RPL9 | ribosomal protein L9 | -0.0271005 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0270241 |
| RPS29 | ribosomal protein S29 | -0.0267452 |
| RPL27A | ribosomal protein L27a | -0.0259665 |
| RPS5 | ribosomal protein S5 | -0.0256178 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0254908 |
| RPS13 | ribosomal protein S13 | -0.0254441 |
| YBX3 | Y box binding protein 3 | -0.0251726 |
| PFN1 | profilin 1 | -0.0250355 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0249976 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.0249639 |
| RPLP0 | ribosomal protein, large, P0 | -0.024785 |
| RPS15 | ribosomal protein S15 | -0.0244461 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0243484 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0242953 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0240903 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0237163 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | -0.0236757 |
| RPL5 | ribosomal protein L5 | -0.0235535 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.023395 |
| RPS27 | ribosomal protein S27 | -0.0232265 |
| CDK6 | cyclin-dependent kinase 6 | -0.0225593 |
| RPS4X | ribosomal protein S4, X-linked | -0.022487 |
| CLDN1 | claudin 1 | -0.022229 |
| KLF6 | Kruppel-like factor 6 | -0.0219691 |
| RPS23 | ribosomal protein S23 | -0.0218622 |
| CAVIN1 | caveolae associated protein 1 | -0.0217825 |
| RPL32 | ribosomal protein L32 | -0.0215782 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0211424 |
| SEC62 | SEC62 homolog (S. cerevisiae) | -0.0209036 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0206176 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0200627 |
| RPL13A | ribosomal protein L13a | -0.0198967 |
| GCG | glucagon | -0.0196003 |
| CCNI | cyclin I | -0.0195753 |
| RPL7 | ribosomal protein L7 | -0.0191887 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0191524 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0189239 |
