| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Altretamine perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Altretamine_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.195207 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.171317 |
| FN1 | fibronectin 1 | 0.157605 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.156137 |
| FNDC3B | fibronectin type III domain containing 3B | 0.148732 |
| VEGFA | vascular endothelial growth factor A | 0.120794 |
| ATP13A3 | ATPase type 13A3 | 0.0980725 |
| CADM1 | cell adhesion molecule 1 | 0.0963598 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0935991 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0886742 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0809699 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0768106 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0743404 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0661166 |
| SMAD3 | SMAD family member 3 | 0.0633774 |
| PTK2 | protein tyrosine kinase 2 | 0.0621692 |
| LOXL2 | lysyl oxidase-like 2 | 0.061493 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0597588 |
| CD44 | CD44 molecule (Indian blood group) | 0.0595721 |
| PLEC | plectin | 0.057709 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0560178 |
| NDRG1 | N-myc downstream regulated 1 | 0.055183 |
| COL5A1 | collagen, type V, alpha 1 | 0.054468 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0509144 |
| PDE10A | phosphodiesterase 10A | 0.0496787 |
| COL1A1 | collagen, type I, alpha 1 | 0.0492123 |
| MTSS1 | metastasis suppressor 1 | 0.0489825 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0484987 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0476426 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.0474246 |
| PRELID2 | PRELI domain containing 2 | 0.0472012 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0440527 |
| ARRDC3 | arrestin domain containing 3 | 0.0424875 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0420311 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0416133 |
| NAV2 | neuron navigator 2 | 0.0415691 |
| EGFR | epidermal growth factor receptor | 0.0407987 |
| RUNX1 | runt-related transcription factor 1 | 0.040127 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0396473 |
| TNS1 | tensin 1 | 0.0387467 |
| CCNL1 | cyclin L1 | 0.0382926 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0382686 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0368733 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0366838 |
| B2M | beta-2-microglobulin | 0.0365517 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0365482 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0363972 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0362122 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0358127 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0352177 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.035162 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0342462 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0340719 |
| ECE1 | endothelin converting enzyme 1 | 0.0338493 |
| VMP1 | vacuole membrane protein 1 | 0.0333348 |
| KIAA1217 | KIAA1217 | 0.0331185 |
| APP | amyloid beta (A4) precursor protein | 0.0325321 |
| PPP3CC | protein phosphatase 3, catalytic subunit, gamma isozyme | 0.0324839 |
| ADM | adrenomedullin | 0.0321572 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0318708 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0318076 |
| COL1A2 | collagen, type I, alpha 2 | 0.0316367 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0315453 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0312022 |
| CLIC4 | chloride intracellular channel 4 | 0.0309921 |
| FLNA | filamin A, alpha | 0.030921 |
| RBM39 | RNA binding motif protein 39 | 0.0308666 |
| DST | dystonin | 0.0306231 |
| MRTFA | myocardin related transcription factor A | 0.0301177 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0297435 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0296712 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0294193 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.029188 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0288255 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.028758 |
| MED13L | mediator complex subunit 13-like | 0.0286164 |
| RPL37A | ribosomal protein L37a | 0.0285207 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.02846 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0280649 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0277007 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0276741 |
| FMNL2 | formin-like 2 | 0.0276486 |
| SPAG9 | sperm associated antigen 9 | 0.0272021 |
| FAM20C | family with sequence similarity 20, member C | 0.0271955 |
| TFG | TRK-fused gene | 0.0270944 |
| MEF2A | myocyte enhancer factor 2A | 0.0266548 |
| RARB | retinoic acid receptor, beta | 0.0266543 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0266099 |
| GOLGA4 | golgin A4 | 0.0264533 |
| ZNF292 | zinc finger protein 292 | 0.0263584 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.02589 |
| OGA | O-GlcNAcase | 0.0258858 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.0255922 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.025126 |
| QKI | QKI, KH domain containing, RNA binding | 0.0250804 |
| COL4A2 | collagen, type IV, alpha 2 | 0.0248512 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0248052 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0246537 |
| USP34 | ubiquitin specific peptidase 34 | 0.0245744 |
| PDE8A | phosphodiesterase 8A | 0.024567 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.22299 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.181499 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.126031 |
| VIM | vimentin | -0.0862181 |
| MT2A | metallothionein 2A | -0.0636974 |
| LOX | lysyl oxidase | -0.0549413 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0548192 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0501926 |
| STC1 | stanniocalcin 1 | -0.0454866 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0440056 |
| TMSB10 | thymosin beta 10 | -0.0437682 |
| AHNAK | AHNAK nucleoprotein | -0.0390084 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0372581 |
| MAP1B | microtubule-associated protein 1B | -0.0344238 |
| EGR1 | early growth response 1 | -0.0339358 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0318937 |
| CANX | calnexin | -0.0305613 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0283239 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0281508 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0278651 |
| FBN1 | fibrillin 1 | -0.0271308 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0256642 |
| PDLIM5 | PDZ and LIM domain 5 | -0.025042 |
| RND3 | Rho family GTPase 3 | -0.0249519 |
| S100A10 | S100 calcium binding protein A10 | -0.0245791 |
| DUSP6 | dual specificity phosphatase 6 | -0.023404 |
| PALLD | palladin, cytoskeletal associated protein | -0.0229637 |
| MYADM | myeloid-associated differentiation marker | -0.0223542 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0221093 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0211994 |
| KLF6 | Kruppel-like factor 6 | -0.0205827 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.020185 |
| H1-0 | H1.0 linker histone | -0.0197541 |
| HMGA1 | high mobility group AT-hook 1 | -0.01962 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0195735 |
| TAGLN2 | transgelin 2 | -0.019422 |
| LMAN1 | lectin, mannose-binding, 1 | -0.019403 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0193783 |
| CLMP | CXADR-like membrane protein | -0.0192331 |
| RSU1 | Ras suppressor protein 1 | -0.0191422 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0189314 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.0187775 |
| GOLGB1 | golgin B1 | -0.0186387 |
| FOXP1 | forkhead box P1 | -0.0179011 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.017494 |
| RRBP1 | ribosome binding protein 1 | -0.0173813 |
| SEC24D | SEC24 family member D | -0.0172729 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0170356 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0166822 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0164772 |
| VCL | vinculin | -0.0163972 |
| MMP3 | matrix metallopeptidase 3 | -0.0161371 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0159778 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0158106 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0156104 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0155599 |
| CAVIN1 | caveolae associated protein 1 | -0.0148244 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0145412 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0141548 |
| ZNF644 | zinc finger protein 644 | -0.0141517 |
| HDLBP | high density lipoprotein binding protein | -0.0140409 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | -0.0140291 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0139081 |
| CENPE | centromere protein E, 312kDa | -0.0139011 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0139005 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0138973 |
| HM13 | histocompatibility (minor) 13 | -0.013893 |
| GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 | -0.0138343 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0137224 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0135629 |
| MT1X | metallothionein 1X | -0.0134949 |
| CEP350 | centrosomal protein 350kDa | -0.0133481 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0133409 |
| INHBA | inhibin, beta A | -0.0133241 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0130055 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0128869 |
| PCNP | PEST proteolytic signal containing nuclear protein | -0.0128131 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0128072 |
| LTN1 | listerin E3 ubiquitin protein ligase 1 | -0.0126122 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0125454 |
| NUP98 | nucleoporin 98kDa | -0.012515 |
| GLIS3 | GLIS family zinc finger 3 | -0.012507 |
| LMO4 | LIM domain only 4 | -0.0123969 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.012229 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0121259 |
| TRAM1 | translocation associated membrane protein 1 | -0.0120762 |
| KDELR1 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 | -0.0118134 |
| MTDH | metadherin | -0.0117887 |
| AHI1 | Abelson helper integration site 1 | -0.0116785 |
| NEK11 | NIMA-related kinase 11 | -0.0116746 |
| DGKI | diacylglycerol kinase, iota | -0.0115938 |
| FAM114A1 | family with sequence similarity 114, member A1 | -0.0115516 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0114349 |
| FAF2 | Fas associated factor family member 2 | -0.0113767 |
| WASF2 | WAS protein family, member 2 | -0.0113446 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.011285 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.011218 |
| ZMYM4 | zinc finger, MYM-type 4 | -0.0111857 |
| MCPH1 | microcephalin 1 | -0.0111692 |
| SEPTIN2 | septin 2 | -0.0111365 |
