| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Altretamine perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Altretamine_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.365028 |
| FN1 | fibronectin 1 | 0.219579 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.116375 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.102499 |
| ENO1 | enolase 1, (alpha) | 0.101013 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0964291 |
| KRT8 | keratin 8, type II | 0.0964008 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0960338 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0840394 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0763699 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.075293 |
| TF | transferrin | 0.0721875 |
| PEG3 | paternally expressed 3 | 0.0696378 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | 0.06955 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0624299 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0622925 |
| APOB | apolipoprotein B | 0.0612413 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.060149 |
| LYZ | lysozyme | 0.0585971 |
| KRT18 | keratin 18, type I | 0.0567669 |
| CALR | calreticulin | 0.0541887 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0514397 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.048493 |
| TMEM123 | transmembrane protein 123 | 0.0477655 |
| SESTD1 | SEC14 and spectrin domains 1 | 0.0466915 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0456944 |
| VEGFA | vascular endothelial growth factor A | 0.0450577 |
| APOA1 | apolipoprotein A-I | 0.0442844 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | 0.0427937 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | 0.0426116 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.042276 |
| LMCD1 | LIM and cysteine-rich domains 1 | 0.0421487 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0418991 |
| FAT1 | FAT atypical cadherin 1 | 0.0415824 |
| ZNF292 | zinc finger protein 292 | 0.0397603 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0384424 |
| STK17A | serine/threonine kinase 17a | 0.0364712 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.035649 |
| APOA2 | apolipoprotein A-II | 0.0354817 |
| RASGRF2 | Ras protein-specific guanine nucleotide-releasing factor 2 | 0.0350772 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0348654 |
| PTK2 | protein tyrosine kinase 2 | 0.0344584 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0340751 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0338258 |
| CRLS1 | cardiolipin synthase 1 | 0.0337024 |
| DSPP | dentin sialophosphoprotein | 0.0329643 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | 0.032833 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.032646 |
| MATN3 | matrilin 3 | 0.0320133 |
| ACTG1 | actin gamma 1 | 0.0308053 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.030754 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0306639 |
| AHR | aryl hydrocarbon receptor | 0.0305435 |
| SBF2 | SET binding factor 2 | 0.0303583 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0302937 |
| TPM4 | tropomyosin 4 | 0.0297528 |
| APP | amyloid beta (A4) precursor protein | 0.0297219 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | 0.0296811 |
| EGR1 | early growth response 1 | 0.0296682 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0295847 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0292614 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0288886 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0288855 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.028215 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0279698 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0277913 |
| ACSS3 | acyl-CoA synthetase short-chain family member 3 | 0.0273789 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | 0.0273415 |
| GPAM | glycerol-3-phosphate acyltransferase, mitochondrial | 0.0268512 |
| ARHGAP9 | Rho GTPase activating protein 9 | 0.0266951 |
| ITGAV | integrin, alpha V | 0.0265169 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | 0.0260204 |
| PGK1 | phosphoglycerate kinase 1 | 0.0258872 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.025765 |
| TXNRD1 | thioredoxin reductase 1 | 0.0255884 |
| KIZ | kizuna centrosomal protein | 0.0253897 |
| PLIN2 | perilipin 2 | 0.0251976 |
| WAC | WW domain containing adaptor with coiled-coil | 0.025143 |
| GABBR1 | gamma-aminobutyric acid (GABA) B receptor, 1 | 0.024753 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0245675 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0243904 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.0234303 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0231422 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0230347 |
| CALD1 | caldesmon 1 | 0.022883 |
| DNAJA2 | DnaJ (Hsp40) homolog, subfamily A, member 2 | 0.0228588 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0227245 |
| MSI2 | musashi RNA-binding protein 2 | 0.022553 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | 0.0223954 |
| CLTB | clathrin, light chain B | 0.0223583 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0223465 |
| AFDN | afadin, adherens junction formation factor | 0.022297 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0220515 |
| MAPRE1 | microtubule-associated protein, RP/EB family, member 1 | 0.0219208 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | 0.0218613 |
| ENAH | enabled homolog (Drosophila) | 0.02176 |
| TPD52 | tumor protein D52 | 0.0217499 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0216533 |
| B2M | beta-2-microglobulin | 0.0216319 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0215625 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.180297 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.142928 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.13243 |
| IGF2 | insulin-like growth factor 2 | -0.112261 |
| MT2A | metallothionein 2A | -0.0940517 |
| SVIL | supervillin | -0.0707653 |
| RPL11 | ribosomal protein L11 | -0.0704204 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.0677836 |
| RPS6 | ribosomal protein S6 | -0.0629542 |
| PDGFB | platelet-derived growth factor beta polypeptide | -0.0605459 |
| SMAD3 | SMAD family member 3 | -0.0591237 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0555486 |
| RPS2 | ribosomal protein S2 | -0.0515366 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0509735 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.050026 |
| RPL37A | ribosomal protein L37a | -0.0450405 |
| EPAS1 | endothelial PAS domain protein 1 | -0.043709 |
| NDRG1 | N-myc downstream regulated 1 | -0.0433621 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0424477 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0415728 |
| BCL2L1 | BCL2-like 1 | -0.0409279 |
| RBM39 | RNA binding motif protein 39 | -0.0390568 |
| FOXP1 | forkhead box P1 | -0.0375321 |
| ATXN1 | ataxin 1 | -0.0364394 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0352576 |
| UBXN4 | UBX domain protein 4 | -0.0351092 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0348701 |
| ITGB5 | integrin, beta 5 | -0.0341334 |
| LCN2 | lipocalin 2 | -0.0336989 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0333741 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0333641 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0328638 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0325826 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0323542 |
| FLNB | filamin B, beta | -0.032178 |
| RPL36 | ribosomal protein L36 | -0.0318891 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0315779 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0314455 |
| PAPOLA | poly(A) polymerase alpha | -0.0312886 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0312845 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0312401 |
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 | -0.0309486 |
| RPL38 | ribosomal protein L38 | -0.0306373 |
| RPL9 | ribosomal protein L9 | -0.0305089 |
| PRKCA | protein kinase C, alpha | -0.0305046 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0304704 |
| ZSWIM5 | zinc finger, SWIM-type containing 5 | -0.0295429 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0290676 |
| USP34 | ubiquitin specific peptidase 34 | -0.0281353 |
| HPCAL1 | hippocalcin-like 1 | -0.028062 |
| FAM107B | family with sequence similarity 107, member B | -0.0279851 |
| RPL30 | ribosomal protein L30 | -0.0278023 |
| MED13L | mediator complex subunit 13-like | -0.0274061 |
| KYNU | kynureninase | -0.0271759 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0268929 |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 | -0.0260517 |
| GOLGB1 | golgin B1 | -0.0254693 |
| RPL37 | ribosomal protein L37 | -0.0254364 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.0247987 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.024545 |
| PTMA | prothymosin, alpha | -0.0244258 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0243714 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.024362 |
| RPL19 | ribosomal protein L19 | -0.024315 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0242321 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0241493 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.0239683 |
| AAK1 | AP2 associated kinase 1 | -0.0237558 |
| RPL6 | ribosomal protein L6 | -0.0235428 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0234432 |
| RBM33 | RNA binding motif protein 33 | -0.0234278 |
| TNFSF14 | tumor necrosis factor (ligand) superfamily, member 14 | -0.0231165 |
| HMGA1 | high mobility group AT-hook 1 | -0.0230994 |
| RASA2 | RAS p21 protein activator 2 | -0.0230796 |
| RPL26 | ribosomal protein L26 | -0.0230161 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.0229963 |
| RPS16 | ribosomal protein S16 | -0.0229147 |
| RIGI | RNA sensor RIG-I | -0.022888 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0228476 |
| RPLP1 | ribosomal protein, large, P1 | -0.0224321 |
| ENKUR | enkurin, TRPC channel interacting protein | -0.0221914 |
| INTS6 | integrator complex subunit 6 | -0.0215455 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0215148 |
| SDC4 | syndecan 4 | -0.0214676 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0213181 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0212334 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0209989 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0208911 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0208386 |
| SNX9 | sorting nexin 9 | -0.0207776 |
| RPS5 | ribosomal protein S5 | -0.0207408 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0206897 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0206293 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | -0.0206233 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | -0.0205938 |
| CLTC | clathrin, heavy chain (Hc) | -0.020512 |
| RPL7 | ribosomal protein L7 | -0.0203852 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0202283 |
| MCL1 | myeloid cell leukemia 1 | -0.0202281 |
| SKI | SKI proto-oncogene | -0.0201632 |
