| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Altretamine perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Altretamine_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MTSS1 | metastasis suppressor 1 | 0.0896952 |
| MEF2A | myocyte enhancer factor 2A | 0.0839835 |
| PLEC | plectin | 0.0689084 |
| MSN | moesin | 0.067628 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0630695 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0594775 |
| MYOF | myoferlin | 0.0543941 |
| KIAA1217 | KIAA1217 | 0.0534678 |
| ASPH | aspartate beta-hydroxylase | 0.0517106 |
| PODXL | podocalyxin-like | 0.0516096 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0498746 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0479657 |
| SMAD3 | SMAD family member 3 | 0.0476088 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0454179 |
| LAMA5 | laminin, alpha 5 | 0.0436238 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0426709 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.042315 |
| TGM2 | transglutaminase 2 | 0.0421247 |
| PRELID2 | PRELI domain containing 2 | 0.0414497 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.0403414 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0390535 |
| AOPEP | aminopeptidase O (putative) | 0.0379428 |
| SMYD3 | SET and MYND domain containing 3 | 0.0361746 |
| NDRG1 | N-myc downstream regulated 1 | 0.0352948 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0346424 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.0344074 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0344014 |
| BCL2L1 | BCL2-like 1 | 0.033665 |
| DOK5 | docking protein 5 | 0.0336263 |
| FOXO1 | forkhead box O1 | 0.0331872 |
| NAV2 | neuron navigator 2 | 0.032687 |
| JAG1 | jagged 1 | 0.0325392 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | 0.0323113 |
| SH3PXD2A | SH3 and PX domains 2A | 0.0319747 |
| FOXP1 | forkhead box P1 | 0.0314575 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0307021 |
| PTK2 | protein tyrosine kinase 2 | 0.0304822 |
| CD44 | CD44 molecule (Indian blood group) | 0.0302862 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0295712 |
| DST | dystonin | 0.0291189 |
| RAD51B | RAD51 paralog B | 0.0282367 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 | 0.0281329 |
| SLK | STE20-like kinase | 0.0279559 |
| PCDH1 | protocadherin 1 | 0.0275682 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0274727 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0268579 |
| DOCK5 | dedicator of cytokinesis 5 | 0.026781 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.026744 |
| CUL4B | cullin 4B | 0.0262992 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0260914 |
| OGA | O-GlcNAcase | 0.0257802 |
| TPM3 | tropomyosin 3 | 0.0256453 |
| ARRDC3 | arrestin domain containing 3 | 0.0255689 |
| LMO7 | LIM domain 7 | 0.0255641 |
| XPO1 | exportin 1 | 0.0254823 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0253848 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0248846 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.024859 |
| RIN2 | Ras and Rab interactor 2 | 0.0248401 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0247984 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | 0.0247292 |
| SEPTIN9 | septin 9 | 0.0244928 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0243756 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0238946 |
| EPHA2 | EPH receptor A2 | 0.0238371 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0233107 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0232674 |
| ZNF292 | zinc finger protein 292 | 0.0229242 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0229151 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0228957 |
| ANO6 | anoctamin 6 | 0.0227255 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0225971 |
| DIDO1 | death inducer-obliterator 1 | 0.0225535 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.022309 |
| FN1 | fibronectin 1 | 0.0222769 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0222115 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0219125 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0219094 |
| MEGF6 | multiple EGF-like-domains 6 | 0.0218179 |
| NECTIN1 | nectin cell adhesion molecule 1 | 0.0215663 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | 0.0215625 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0213248 |
| ANXA11 | annexin A11 | 0.0212808 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0212605 |
| CAPRIN2 | caprin family member 2 | 0.0212019 |
| ACTN4 | actinin, alpha 4 | 0.0211565 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0210857 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | 0.0210075 |
| UHRF2 | ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase | 0.0208559 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0206833 |
| YAP1 | Yes-associated protein 1 | 0.0206609 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0204813 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0203223 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0201702 |
| ITGB4 | integrin, beta 4 | 0.0200453 |
| KIF16B | kinesin family member 16B | 0.0200283 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0199801 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0199791 |
| ARHGAP23 | Rho GTPase activating protein 23 | 0.0198697 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0197923 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.279056 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.173813 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.147297 |
| PTMA | prothymosin, alpha | -0.114723 |
| TMSB10 | thymosin beta 10 | -0.100008 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.091846 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0822613 |
| AHNAK | AHNAK nucleoprotein | -0.0600375 |
| S100A10 | S100 calcium binding protein A10 | -0.0586815 |
| CLU | clusterin | -0.0574547 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0565005 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0544305 |
| GNAS | GNAS complex locus | -0.0538078 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0536338 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0512133 |
| B2M | beta-2-microglobulin | -0.0475123 |
| RPS21 | ribosomal protein S21 | -0.0456406 |
| LMNA | lamin A/C | -0.045284 |
| RPS8 | ribosomal protein S8 | -0.0442755 |
| IGF2 | insulin-like growth factor 2 | -0.0440165 |
| CANX | calnexin | -0.043221 |
| TMSB4X | thymosin beta 4, X-linked | -0.042231 |
| MT2A | metallothionein 2A | -0.0418227 |
| EMP1 | epithelial membrane protein 1 | -0.0415951 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0395732 |
| HLA-E | major histocompatibility complex, class I, E | -0.0393842 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0392727 |
| CALU | calumenin | -0.038207 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0379738 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0363932 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0359262 |
| HLA-B | major histocompatibility complex, class I, B | -0.0355238 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0354463 |
| RPS6 | ribosomal protein S6 | -0.0351084 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0351051 |
| FLNB | filamin B, beta | -0.0346278 |
| CAVIN1 | caveolae associated protein 1 | -0.0342743 |
| HM13 | histocompatibility (minor) 13 | -0.0338112 |
| PRSS23 | protease, serine, 23 | -0.0336437 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0332868 |
| MECOM | MDS1 and EVI1 complex locus | -0.0328448 |
| SQLE | squalene epoxidase | -0.0321113 |
| RPS19 | ribosomal protein S19 | -0.0318128 |
| RPL12 | ribosomal protein L12 | -0.031577 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0311641 |
| RPLP1 | ribosomal protein, large, P1 | -0.0309329 |
| MORF4L2 | mortality factor 4 like 2 | -0.0308514 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0306572 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0306021 |
| CALR | calreticulin | -0.0301068 |
| THBD | thrombomodulin | -0.0299695 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0299615 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0298464 |
| CD9 | CD9 molecule | -0.0295094 |
| RPL11 | ribosomal protein L11 | -0.0294692 |
| S100A2 | S100 calcium binding protein A2 | -0.0289481 |
| KRT17 | keratin 17, type I | -0.0287787 |
| ARPC5 | actin related protein 2/3 complex, subunit 5, 16kDa | -0.0287671 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0284785 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0275256 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0274844 |
| S100A11 | S100 calcium binding protein A11 | -0.0274645 |
| GOLGA4 | golgin A4 | -0.0274568 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0274511 |
| RPLP2 | ribosomal protein, large, P2 | -0.0271566 |
| S100A6 | S100 calcium binding protein A6 | -0.0271176 |
| HDLBP | high density lipoprotein binding protein | -0.0265137 |
| RPL8 | ribosomal protein L8 | -0.0263911 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0262045 |
| S100A9 | S100 calcium binding protein A9 | -0.0261659 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0258235 |
| FSCN1 | fascin actin-bundling protein 1 | -0.024948 |
| WASF2 | WAS protein family, member 2 | -0.0249288 |
| PGK1 | phosphoglycerate kinase 1 | -0.024863 |
| MT1X | metallothionein 1X | -0.0243773 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0243439 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.024166 |
| S100A4 | S100 calcium binding protein A4 | -0.0240152 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0237112 |
| LDHA | lactate dehydrogenase A | -0.0236487 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0234887 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0230014 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0229273 |
| RPL32 | ribosomal protein L32 | -0.0227823 |
| RACK1 | receptor for activated C kinase 1 | -0.0226824 |
| RPL34 | ribosomal protein L34 | -0.0226747 |
| RPS3 | ribosomal protein S3 | -0.0226416 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0226015 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0225186 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0224671 |
| TAGLN2 | transgelin 2 | -0.0224448 |
| RPL26 | ribosomal protein L26 | -0.0223505 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.022307 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0222799 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0221459 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0221102 |
| DUSP6 | dual specificity phosphatase 6 | -0.0220971 |
| RPS27A | ribosomal protein S27a | -0.0220157 |
| RPL7A | ribosomal protein L7a | -0.021871 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0216928 |
