| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Altretamine perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Altretamine_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DST | dystonin | 0.12419 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.119513 |
| TP63 | tumor protein p63 | 0.0966734 |
| TMSB4X | thymosin beta 4, X-linked | 0.0837445 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0701513 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0653547 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0641954 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0574526 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0568129 |
| RUNX1 | runt-related transcription factor 1 | 0.0548387 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0542911 |
| ENO1 | enolase 1, (alpha) | 0.0518819 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0510502 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0500509 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0458472 |
| EHBP1 | EH domain binding protein 1 | 0.0454227 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0451536 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0450922 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0444093 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0441834 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0437238 |
| APP | amyloid beta (A4) precursor protein | 0.0436101 |
| SPAG9 | sperm associated antigen 9 | 0.0427145 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0404756 |
| CADM2 | cell adhesion molecule 2 | 0.0386651 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0371345 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0369753 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0366937 |
| RBM39 | RNA binding motif protein 39 | 0.0365024 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0363527 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0358546 |
| CCNL1 | cyclin L1 | 0.0356934 |
| TNS3 | tensin 3 | 0.0355275 |
| ZNF292 | zinc finger protein 292 | 0.0355016 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0352181 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0351994 |
| CFAP299 | cilia and flagella associated protein 299 | 0.034959 |
| EFNA5 | ephrin-A5 | 0.034359 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0343225 |
| PLK2 | polo-like kinase 2 | 0.0336072 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0334003 |
| HDAC9 | histone deacetylase 9 | 0.0327141 |
| WDR43 | WD repeat domain 43 | 0.0326144 |
| PGK1 | phosphoglycerate kinase 1 | 0.0324456 |
| SQSTM1 | sequestosome 1 | 0.0323102 |
| SET | SET nuclear proto-oncogene | 0.0312517 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.031193 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0308793 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0303658 |
| NCKAP1 | NCK-associated protein 1 | 0.0302366 |
| UBC | ubiquitin C | 0.0301454 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0299796 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0297961 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.029791 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0293174 |
| TFRC | transferrin receptor | 0.0291891 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0286632 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0285054 |
| NUP58 | nucleoporin 58 | 0.0282535 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0281135 |
| EPHA4 | EPH receptor A4 | 0.0280818 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0278711 |
| KRT18 | keratin 18, type I | 0.0278302 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.027691 |
| SMYD3 | SET and MYND domain containing 3 | 0.0270229 |
| MATR3 | matrin 3 | 0.0270202 |
| RAD51B | RAD51 paralog B | 0.0266638 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0264572 |
| TMEM123 | transmembrane protein 123 | 0.0261763 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0259168 |
| CAPRIN2 | caprin family member 2 | 0.0259114 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0258995 |
| EREG | epiregulin | 0.0254863 |
| DENND1A | DENN/MADD domain containing 1A | 0.0253411 |
| MYOF | myoferlin | 0.0251998 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0246543 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0246317 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0244773 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0237831 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0237551 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0236375 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0234272 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0233582 |
| RPS2 | ribosomal protein S2 | 0.0233231 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.023091 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0228061 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.0227258 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0226094 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0225045 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0224207 |
| MEF2A | myocyte enhancer factor 2A | 0.0224044 |
| NEK7 | NIMA-related kinase 7 | 0.0223109 |
| PDE10A | phosphodiesterase 10A | 0.0219964 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0219176 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.021902 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0217118 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0215447 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0214416 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.021436 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0213494 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.270775 |
| VIM | vimentin | -0.169692 |
| MT2A | metallothionein 2A | -0.159112 |
| TMSB10 | thymosin beta 10 | -0.090735 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0781826 |
| PTMA | prothymosin, alpha | -0.0616952 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0504983 |
| HMGA1 | high mobility group AT-hook 1 | -0.0476372 |
| RPL35A | ribosomal protein L35a | -0.0466311 |
| TXNIP | thioredoxin interacting protein | -0.045853 |
| LOC112694756 | uncharaterized LOC112694756 | -0.045558 |
| FTL | ferritin, light polypeptide | -0.0443796 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0405728 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0365259 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | -0.0357795 |
| POTEF | POTE ankyrin domain family, member F | -0.0339585 |
| CENPF | centromere protein F, 350/400kDa | -0.0329115 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0322709 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0314642 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0296146 |
| EGR1 | early growth response 1 | -0.0295638 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0293457 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0257071 |
| MT1X | metallothionein 1X | -0.0250716 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0248723 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.0239336 |
| RPS6 | ribosomal protein S6 | -0.0220299 |
| PFN1 | profilin 1 | -0.021808 |
| CENPE | centromere protein E, 312kDa | -0.0213487 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0211428 |
| TAPBP | TAP binding protein (tapasin) | -0.0198233 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0193947 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0192161 |
| HLA-A | major histocompatibility complex, class I, A | -0.0182416 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0170264 |
| S100A9 | S100 calcium binding protein A9 | -0.0163971 |
| MYADM | myeloid-associated differentiation marker | -0.0163063 |
| PTMS | parathymosin | -0.0157135 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0156872 |
| CCDC88A | coiled-coil domain containing 88A | -0.0156562 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0154709 |
| FLNB | filamin B, beta | -0.0148354 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0147869 |
| TP53 | tumor protein p53 | -0.0145846 |
| SGO2 | shugoshin 2 | -0.0143696 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0143318 |
| CBX3 | chromobox homolog 3 | -0.0141643 |
| NAV2 | neuron navigator 2 | -0.0138619 |
| S100A10 | S100 calcium binding protein A10 | -0.0136217 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0136176 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0134802 |
| RPLP1 | ribosomal protein, large, P1 | -0.0134051 |
| GART | phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase | -0.0131209 |
| SEC62 | SEC62 homolog (S. cerevisiae) | -0.0130932 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.012696 |
| MT1E | metallothionein 1E | -0.012678 |
| RPS14 | ribosomal protein S14 | -0.0126625 |
| SON | SON DNA binding protein | -0.0126159 |
| DDX41 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 | -0.0123829 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0123247 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0122926 |
| ATN1 | atrophin 1 | -0.0122705 |
| S100A6 | S100 calcium binding protein A6 | -0.0121126 |
| RPL28 | ribosomal protein L28 | -0.0117921 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0115993 |
| NUCB2 | nucleobindin 2 | -0.0115115 |
| RPL12 | ribosomal protein L12 | -0.0113091 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0112587 |
| SEPTIN7 | septin 7 | -0.0111087 |
| UBA1 | ubiquitin-like modifier activating enzyme 1 | -0.0110056 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | -0.0108291 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.010737 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0106966 |
| KIF14 | kinesin family member 14 | -0.0106749 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | -0.0106494 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0105372 |
| UBE2C | ubiquitin-conjugating enzyme E2C | -0.0105056 |
| RPS13 | ribosomal protein S13 | -0.0104833 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0104041 |
| RPL8 | ribosomal protein L8 | -0.0103971 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0102166 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0102022 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.0101117 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0100789 |
| TBC1D23 | TBC1 domain family, member 23 | -0.00988057 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | -0.00986257 |
| TUBB6 | tubulin, beta 6 class V | -0.00979802 |
| RPS23 | ribosomal protein S23 | -0.0097592 |
| SMC3 | structural maintenance of chromosomes 3 | -0.00973551 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.00972752 |
| RPL19 | ribosomal protein L19 | -0.00970909 |
| TUBA1B | tubulin, alpha 1b | -0.00970517 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.00964453 |
| UBXN4 | UBX domain protein 4 | -0.00957873 |
| WBP2 | WW domain binding protein 2 | -0.00956072 |
| DEK | DEK proto-oncogene | -0.00946348 |
| RBM25 | RNA binding motif protein 25 | -0.00943244 |
| RPL27 | ribosomal protein L27 | -0.00943165 |
| PCBP1 | poly(rC) binding protein 1 | -0.00939266 |
| ZFHX3 | zinc finger homeobox 3 | -0.00935108 |
