| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Altretamine perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Altretamine_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SDK1 | sidekick cell adhesion molecule 1 | 0.140244 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.106194 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.098439 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0975768 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0949419 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0943581 |
| CDH13 | cadherin 13 | 0.0848213 |
| FAM13A | family with sequence similarity 13, member A | 0.0830318 |
| PRELID2 | PRELI domain containing 2 | 0.081316 |
| VEGFA | vascular endothelial growth factor A | 0.0806313 |
| NAV2 | neuron navigator 2 | 0.0742508 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0677043 |
| EFNA5 | ephrin-A5 | 0.0641298 |
| GPC6 | glypican 6 | 0.0626066 |
| FN1 | fibronectin 1 | 0.0593868 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.057874 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0566461 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0547828 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0540199 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0534276 |
| NGLY1 | N-glycanase 1 | 0.0523931 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0493384 |
| ZNF292 | zinc finger protein 292 | 0.0484322 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.0477873 |
| USP34 | ubiquitin specific peptidase 34 | 0.0472487 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0446726 |
| FAM20C | family with sequence similarity 20, member C | 0.0444512 |
| ENO1 | enolase 1, (alpha) | 0.0441945 |
| RUNX2 | runt-related transcription factor 2 | 0.0435679 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0432206 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.0415949 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0410213 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0403385 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0403114 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | 0.0401527 |
| SMAD3 | SMAD family member 3 | 0.0399418 |
| MEF2A | myocyte enhancer factor 2A | 0.039591 |
| RUNX1 | runt-related transcription factor 1 | 0.0387957 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0386307 |
| MTSS1 | metastasis suppressor 1 | 0.0375834 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0372447 |
| HELZ | helicase with zinc finger | 0.0372084 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0370576 |
| YEATS2 | YEATS domain containing 2 | 0.0369054 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.0362597 |
| B2M | beta-2-microglobulin | 0.0360823 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0359124 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | 0.0356805 |
| CDCP1 | CUB domain containing protein 1 | 0.0356688 |
| NBAS | neuroblastoma amplified sequence | 0.035348 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0351075 |
| CEP250 | centrosomal protein 250kDa | 0.0348726 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | 0.0348365 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0342458 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.03396 |
| ADD3 | adducin 3 (gamma) | 0.033748 |
| PYGL | phosphorylase, glycogen, liver | 0.033289 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0331589 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.032609 |
| OXR1 | oxidation resistance 1 | 0.0324017 |
| ANO6 | anoctamin 6 | 0.0321491 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0318435 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0313414 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0309172 |
| VEGFC | vascular endothelial growth factor C | 0.0303556 |
| ASPH | aspartate beta-hydroxylase | 0.0302208 |
| CA12 | carbonic anhydrase XII | 0.0299825 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0299184 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | 0.0297777 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0296705 |
| PCBP2 | poly(rC) binding protein 2 | 0.0296578 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0295596 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0295423 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0293164 |
| LRRC8C | leucine rich repeat containing 8 family, member C | 0.0288863 |
| PFKP | phosphofructokinase, platelet | 0.0285185 |
| DTNA | dystrobrevin, alpha | 0.0281054 |
| RARB | retinoic acid receptor, beta | 0.027546 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0273083 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0272516 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.0269905 |
| METTL15 | methyltransferase like 15 | 0.026821 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0266524 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0265449 |
| PTK2 | protein tyrosine kinase 2 | 0.0262797 |
| PKM | pyruvate kinase, muscle | 0.0261836 |
| APP | amyloid beta (A4) precursor protein | 0.0261752 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | 0.0261175 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0257331 |
| SLTM | SAFB-like, transcription modulator | 0.0257306 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0256545 |
| C1GALT1 | core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 | 0.0256485 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.025563 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0253271 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0252073 |
| BBX | bobby sox homolog (Drosophila) | 0.0250728 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.0250296 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0249303 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.024853 |
| FBXL13 | F-box and leucine-rich repeat protein 13 | 0.0247295 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.190842 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.150659 |
| CD44 | CD44 molecule (Indian blood group) | -0.149884 |
| GLCCI1 | glucocorticoid induced 1 | -0.1001 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0986685 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0964495 |
| VIM | vimentin | -0.0822352 |
| TMSB10 | thymosin beta 10 | -0.081615 |
| NTN4 | netrin 4 | -0.0815927 |
| OSMR | oncostatin M receptor | -0.0731252 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0622517 |
| RBM39 | RNA binding motif protein 39 | -0.060043 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0597314 |
| FTL | ferritin, light polypeptide | -0.0590286 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0578905 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.057081 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | -0.0545438 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0541564 |
| LOX | lysyl oxidase | -0.0536191 |
| KYNU | kynureninase | -0.0527607 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0498882 |
| RPLP1 | ribosomal protein, large, P1 | -0.0488719 |
| TNNC1 | troponin C type 1 (slow) | -0.0476757 |
| KSR1 | kinase suppressor of ras 1 | -0.0465708 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0449355 |
| VCL | vinculin | -0.0447265 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0447223 |
| IL1R1 | interleukin 1 receptor, type I | -0.0445196 |
| IER3 | immediate early response 3 | -0.0424275 |
| TMEM263 | transmembrane protein 263 | -0.041548 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0407365 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0407277 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0406539 |
| SYAP1 | synapse associated protein 1 | -0.0404493 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0399713 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.036129 |
| FBXO11 | F-box protein 11 | -0.0360105 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0357243 |
| EGR1 | early growth response 1 | -0.0348765 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0348179 |
| S100A6 | S100 calcium binding protein A6 | -0.0343167 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0341711 |
| HEG1 | heart development protein with EGF-like domains 1 | -0.0335465 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0334654 |
| VRK2 | vaccinia related kinase 2 | -0.0329341 |
| RPLP0 | ribosomal protein, large, P0 | -0.0321936 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.032124 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0320048 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0317274 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0316025 |
| RPL35A | ribosomal protein L35a | -0.0310913 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0309034 |
| HDLBP | high density lipoprotein binding protein | -0.0308256 |
| CCNI | cyclin I | -0.0304256 |
| RNF24 | ring finger protein 24 | -0.0301533 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0300901 |
| CALU | calumenin | -0.0299332 |
| RPL32 | ribosomal protein L32 | -0.0297971 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0296459 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | -0.0291899 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0287855 |
| OXSR1 | oxidative stress responsive 1 | -0.0287586 |
| BPTF | bromodomain PHD finger transcription factor | -0.0284437 |
| MT2A | metallothionein 2A | -0.0280682 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.027661 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0275991 |
| GLIPR1 | GLI pathogenesis-related 1 | -0.0273054 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0273014 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0271549 |
| STC1 | stanniocalcin 1 | -0.0270498 |
| AADAC | arylacetamide deacetylase | -0.0265125 |
| S100A10 | S100 calcium binding protein A10 | -0.0259868 |
| PTMA | prothymosin, alpha | -0.0249241 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0247287 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0245796 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0242094 |
| RPS21 | ribosomal protein S21 | -0.0241938 |
| USP15 | ubiquitin specific peptidase 15 | -0.0237184 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0236174 |
| EVA1C | eva-1 homolog C (C. elegans) | -0.0233651 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0232503 |
| RPL19 | ribosomal protein L19 | -0.0228868 |
| SLC30A7 | solute carrier family 30 (zinc transporter), member 7 | -0.0227206 |
| WASF2 | WAS protein family, member 2 | -0.0224057 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0221297 |
| ANXA2 | annexin A2 | -0.0220144 |
| TXLNG | taxilin gamma | -0.0219005 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0219005 |
| HTRA3 | HtrA serine peptidase 3 | -0.0216995 |
| DUSP16 | dual specificity phosphatase 16 | -0.0213314 |
| RPS6 | ribosomal protein S6 | -0.0213167 |
| RPL23 | ribosomal protein L23 | -0.0209981 |
| RAB5A | RAB5A, member RAS oncogene family | -0.0209889 |
| NLK | nemo-like kinase | -0.0209641 |
| ANKRD28 | ankyrin repeat domain 28 | -0.020945 |
| CANX | calnexin | -0.0206456 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.020606 |
| COL12A1 | collagen, type XII, alpha 1 | -0.0205685 |
| CLIC4 | chloride intracellular channel 4 | -0.0205197 |
| GNAS | GNAS complex locus | -0.0203336 |
