| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Altretamine perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Altretamine_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.10147 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.10017 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0934788 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.085113 |
| PRELID2 | PRELI domain containing 2 | 0.0806308 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0776572 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0752019 |
| RUNX1 | runt-related transcription factor 1 | 0.0751899 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0745129 |
| SLK | STE20-like kinase | 0.0726907 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0712534 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0704831 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0703261 |
| NF1 | neurofibromin 1 | 0.0700186 |
| NBAS | neuroblastoma amplified sequence | 0.0680467 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0676365 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0658448 |
| TPM4 | tropomyosin 4 | 0.0654618 |
| RBM15 | RNA binding motif protein 15 | 0.0646077 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0643885 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0633475 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0622913 |
| MSI2 | musashi RNA-binding protein 2 | 0.0612465 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0594976 |
| FNDC3B | fibronectin type III domain containing 3B | 0.059354 |
| EZR | ezrin | 0.0567531 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0524773 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0514882 |
| GOLGA4 | golgin A4 | 0.051358 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0494432 |
| TXNIP | thioredoxin interacting protein | 0.0493985 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0493256 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0477151 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0467012 |
| CANX | calnexin | 0.0462808 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.045666 |
| EGFR | epidermal growth factor receptor | 0.0430871 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0430656 |
| JMJD1C | jumonji domain containing 1C | 0.0428405 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0424233 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0423449 |
| SQSTM1 | sequestosome 1 | 0.0408501 |
| PRKCA | protein kinase C, alpha | 0.04003 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0394137 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0389105 |
| EXOC4 | exocyst complex component 4 | 0.038586 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0384801 |
| ETNK1 | ethanolamine kinase 1 | 0.0371998 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0361705 |
| LRP1B | low density lipoprotein receptor-related protein 1B | 0.0361478 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0350344 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0340272 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.033275 |
| CDCP1 | CUB domain containing protein 1 | 0.032594 |
| CD44 | CD44 molecule (Indian blood group) | 0.0322647 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0316728 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0311817 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0301642 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0268592 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | 0.0264051 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0260013 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0258872 |
| SLTM | SAFB-like, transcription modulator | 0.0251962 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0233219 |
| HMGA2 | high mobility group AT-hook 2 | 0.0226226 |
| RBM26 | RNA binding motif protein 26 | 0.0216675 |
| RAB1A | RAB1A, member RAS oncogene family | 0.020716 |
| TPD52 | tumor protein D52 | 0.0204703 |
| ASPH | aspartate beta-hydroxylase | 0.019755 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0193489 |
| TOP1 | topoisomerase (DNA) I | 0.019343 |
| GPATCH2L | G patch domain containing 2-like | 0.017644 |
| CCNL1 | cyclin L1 | 0.0175722 |
| MORF4L2 | mortality factor 4 like 2 | 0.0163762 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0158679 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0156045 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0151098 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0148481 |
| PARD3 | par-3 family cell polarity regulator | 0.0147613 |
| MCL1 | myeloid cell leukemia 1 | 0.0140726 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0133862 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0131247 |
| MYO1E | myosin IE | 0.0129808 |
| RPL23 | ribosomal protein L23 | 0.0122039 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0119081 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.0112409 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0111008 |
| RPS6 | ribosomal protein S6 | 0.0110805 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.01071 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0106787 |
| ENO1 | enolase 1, (alpha) | 0.00842555 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.00825556 |
| LDHA | lactate dehydrogenase A | 0.00651196 |
| PGK1 | phosphoglycerate kinase 1 | 0.00639923 |
| INHBA | inhibin, beta A | 0.00616906 |
| MMP1 | matrix metallopeptidase 1 | 0.00616839 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.00542678 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.00528163 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.00476247 |
| MED13L | mediator complex subunit 13-like | 0.00451156 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.215617 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.137758 |
| VIM | vimentin | -0.133182 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.124139 |
| EFNA5 | ephrin-A5 | -0.0888228 |
| PTMA | prothymosin, alpha | -0.0838945 |
| NDRG1 | N-myc downstream regulated 1 | -0.0805537 |
| FN1 | fibronectin 1 | -0.0800955 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0745943 |
| IGF2 | insulin-like growth factor 2 | -0.0688488 |
| GPC6 | glypican 6 | -0.0676828 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0633527 |
| FAM13A | family with sequence similarity 13, member A | -0.0629935 |
| TMSB10 | thymosin beta 10 | -0.0627862 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0617862 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0595133 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0592068 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0579449 |
| MT2A | metallothionein 2A | -0.0578296 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0560995 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0553271 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0540146 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0535387 |
| PTK2 | protein tyrosine kinase 2 | -0.0533356 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0516219 |
| RPS16 | ribosomal protein S16 | -0.0509373 |
| SMYD3 | SET and MYND domain containing 3 | -0.0500317 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0486349 |
| OGA | O-GlcNAcase | -0.047664 |
| ITGA6 | integrin, alpha 6 | -0.0460165 |
| NFIA | nuclear factor I/A | -0.0457168 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0450277 |
| RORA | RAR-related orphan receptor A | -0.0449108 |
| FMNL2 | formin-like 2 | -0.0437377 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.043048 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0429591 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0426273 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0418608 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.039899 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0392713 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0387333 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0386631 |
| FTL | ferritin, light polypeptide | -0.0384722 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0367318 |
| PKM | pyruvate kinase, muscle | -0.0362075 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0357829 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0355849 |
| ZNF292 | zinc finger protein 292 | -0.0353183 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.03492 |
| TENM3 | teneurin transmembrane protein 3 | -0.0345528 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0342736 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0333766 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0325746 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0325483 |
| STC1 | stanniocalcin 1 | -0.0306033 |
| RAB10 | RAB10, member RAS oncogene family | -0.0287078 |
| LAMB3 | laminin, beta 3 | -0.0284369 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0281131 |
| GLG1 | golgi glycoprotein 1 | -0.02804 |
| MYOF | myoferlin | -0.0272904 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.0259811 |
| SBF2 | SET binding factor 2 | -0.0251761 |
| RPLP1 | ribosomal protein, large, P1 | -0.0248767 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0245676 |
| GPHN | gephyrin | -0.0242548 |
| RPL35A | ribosomal protein L35a | -0.0236048 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0231157 |
| NRG1 | neuregulin 1 | -0.0224094 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0206054 |
| ANXA2 | annexin A2 | -0.0205304 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0201149 |
| ANO6 | anoctamin 6 | -0.0187211 |
| LMO7 | LIM domain 7 | -0.018699 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0160991 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0159242 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0154962 |
| GOLGB1 | golgin B1 | -0.0150122 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0146203 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0144237 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0142589 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0128808 |
| TXNRD1 | thioredoxin reductase 1 | -0.0127729 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0124258 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0123375 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0100798 |
| BPTF | bromodomain PHD finger transcription factor | -0.00952973 |
| RAD51B | RAD51 paralog B | -0.0094481 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.00837894 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.00697649 |
| SNX13 | sorting nexin 13 | -0.00681947 |
| ARHGAP21 | Rho GTPase activating protein 21 | -0.00562513 |
| SPAG9 | sperm associated antigen 9 | -0.00540381 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.00459687 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0045428 |
| CLTC | clathrin, heavy chain (Hc) | -0.0043034 |
| EXT1 | exostosin glycosyltransferase 1 | -0.00266628 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.00162314 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.00141778 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.00115837 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -7.0036E-4 |
