| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Altretamine perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Altretamine_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.199192 |
| PEG10 | paternally expressed 10 | 0.128647 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.103853 |
| TMSB4X | thymosin beta 4, X-linked | 0.0908798 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0900612 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.0841664 |
| ZNF292 | zinc finger protein 292 | 0.0823755 |
| ARHGAP15 | Rho GTPase activating protein 15 | 0.0810008 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0753219 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0637027 |
| POTEF | POTE ankyrin domain family, member F | 0.0615103 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.059648 |
| THBS1 | thrombospondin 1 | 0.0565855 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0559658 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0558319 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0538469 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0524389 |
| USP3 | ubiquitin specific peptidase 3 | 0.0524108 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0511598 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0508051 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0502096 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0495874 |
| MATR3 | matrin 3 | 0.0492494 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0488471 |
| WDR43 | WD repeat domain 43 | 0.0463908 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0456649 |
| NCKAP1 | NCK-associated protein 1 | 0.0453309 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0452834 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0451666 |
| PDGFC | platelet derived growth factor C | 0.0451281 |
| CALR | calreticulin | 0.0449302 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.04446 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0443636 |
| RLF | rearranged L-myc fusion | 0.0439717 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | 0.0435146 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0434948 |
| TPM3 | tropomyosin 3 | 0.0430138 |
| GPC3 | glypican 3 | 0.0427508 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | 0.0417684 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0415629 |
| COL5A2 | collagen, type V, alpha 2 | 0.040793 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0403982 |
| SEMA3E | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E | 0.0401524 |
| FIGN | fidgetin | 0.0399251 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.03985 |
| EWSR1 | EWS RNA-binding protein 1 | 0.039541 |
| TWSG1 | twisted gastrulation BMP signaling modulator 1 | 0.0393628 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | 0.0393277 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0389265 |
| TXNRD1 | thioredoxin reductase 1 | 0.0388127 |
| CCNL1 | cyclin L1 | 0.038277 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0382085 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0380876 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0377928 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0370267 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.0367317 |
| ANXA5 | annexin A5 | 0.0362943 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0358784 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0358557 |
| RBM39 | RNA binding motif protein 39 | 0.035532 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0352284 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0351617 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0349849 |
| CRY1 | cryptochrome circadian clock 1 | 0.0348842 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0348205 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0342936 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0342794 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.0342792 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0337967 |
| CLTC | clathrin, heavy chain (Hc) | 0.0336461 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0336065 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0333451 |
| MEMO1 | mediator of cell motility 1 | 0.0330305 |
| MTF2 | metal response element binding transcription factor 2 | 0.032088 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0318553 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0317395 |
| TPR | translocated promoter region, nuclear basket protein | 0.031607 |
| USP12 | ubiquitin specific peptidase 12 | 0.0310269 |
| KDM1A | lysine (K)-specific demethylase 1A | 0.030626 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0305353 |
| UPP1 | uridine phosphorylase 1 | 0.0300839 |
| OLA1 | Obg-like ATPase 1 | 0.0300183 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0298395 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0297445 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.029734 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.029711 |
| AZIN1 | antizyme inhibitor 1 | 0.0295643 |
| RTN4 | reticulon 4 | 0.0291338 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0291069 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0290604 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.028981 |
| CALCR | calcitonin receptor | 0.02888 |
| SEC63 | SEC63 homolog (S. cerevisiae) | 0.0288105 |
| NOP58 | NOP58 ribonucleoprotein | 0.0288092 |
| PROS1 | protein S (alpha) | 0.0286508 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0284842 |
| TSR1 | TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) | 0.0283816 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0283512 |
| LHFPL6 | LHFPL tetraspan subfamily member 6 | 0.0283156 |
| RYBP | RING1 and YY1 binding protein | 0.028255 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.123143 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.107799 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.104869 |
| CADM2 | cell adhesion molecule 2 | -0.0919064 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0841854 |
| COL11A1 | collagen, type XI, alpha 1 | -0.0813539 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.0748663 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0741785 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.0705887 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0637857 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0632494 |
| SNX6 | sorting nexin 6 | -0.0630338 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0609809 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.059514 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0573395 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0572541 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0569416 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0566705 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0559181 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0558129 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0550665 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0542107 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0523887 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0516461 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0504874 |
| ATXN2 | ataxin 2 | -0.0496759 |
| RPS6 | ribosomal protein S6 | -0.0485299 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0475937 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0475671 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0467572 |
| NTM | neurotrimin | -0.0437531 |
| NEBL | nebulette | -0.0428498 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0426772 |
| RPL35A | ribosomal protein L35a | -0.0418119 |
| HDAC9 | histone deacetylase 9 | -0.0413529 |
| RPS8 | ribosomal protein S8 | -0.0410366 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0409013 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0404271 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0403851 |
| TMSB10 | thymosin beta 10 | -0.0400904 |
| ZNF217 | zinc finger protein 217 | -0.0398101 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0396175 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0395919 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0393433 |
| RPS16 | ribosomal protein S16 | -0.0376368 |
| INTS6 | integrator complex subunit 6 | -0.0376333 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0375932 |
| COL3A1 | collagen, type III, alpha 1 | -0.0364937 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.036408 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0355911 |
| NF1 | neurofibromin 1 | -0.0349439 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0348767 |
| SMYD3 | SET and MYND domain containing 3 | -0.0348076 |
| PHIP | pleckstrin homology domain interacting protein | -0.0344541 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.0343598 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) | -0.0343384 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0341736 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0340045 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0328027 |
| NRG1 | neuregulin 1 | -0.0327633 |
| KCTD16 | potassium channel tetramerization domain containing 16 | -0.0321524 |
| NHSL1 | NHS-like 1 | -0.0321493 |
| SRPK2 | SRSF protein kinase 2 | -0.0318131 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0317602 |
| GNAS | GNAS complex locus | -0.031756 |
| ATP9A | ATPase, class II, type 9A | -0.0316594 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0314669 |
| CDH19 | cadherin 19, type 2 | -0.0313009 |
| PCDH9 | protocadherin 9 | -0.0313008 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0312481 |
| RPL37 | ribosomal protein L37 | -0.0309221 |
| PCDH7 | protocadherin 7 | -0.0307998 |
| FAM177A1 | family with sequence similarity 177, member A1 | -0.0306578 |
| NXN | nucleoredoxin | -0.0306052 |
| TUT4 | terminal uridylyl transferase 4 | -0.0305333 |
| CUX1 | cut-like homeobox 1 | -0.0305112 |
| UBC | ubiquitin C | -0.0303763 |
| RCOR1 | REST corepressor 1 | -0.0302955 |
| LPIN2 | lipin 2 | -0.0300246 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0297948 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0290718 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0289083 |
| TUBA1B | tubulin, alpha 1b | -0.0288025 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0288024 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0287338 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0284859 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0284423 |
| USH2A | Usher syndrome 2A (autosomal recessive, mild) | -0.0283254 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0281436 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0280484 |
| HMGA2 | high mobility group AT-hook 2 | -0.0278612 |
| CEP350 | centrosomal protein 350kDa | -0.0276941 |
| ACAP2 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 | -0.0270294 |
| TNS3 | tensin 3 | -0.0268538 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0263598 |
| RAB31 | RAB31, member RAS oncogene family | -0.0263168 |
| RPL9 | ribosomal protein L9 | -0.0261511 |
| CDK13 | cyclin-dependent kinase 13 | -0.0261034 |
| SSH2 | slingshot protein phosphatase 2 | -0.0260921 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0257754 |
