| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Altretamine perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Altretamine_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.15121 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.14295 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.123968 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.108022 |
| NAV2 | neuron navigator 2 | 0.106664 |
| FN1 | fibronectin 1 | 0.087931 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0877887 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0823485 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0781911 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.063845 |
| SMAD3 | SMAD family member 3 | 0.0611705 |
| VEGFA | vascular endothelial growth factor A | 0.05385 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0504736 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0497162 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0491481 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.049144 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0459157 |
| OGA | O-GlcNAcase | 0.0451984 |
| PDE10A | phosphodiesterase 10A | 0.0408782 |
| ARRDC3 | arrestin domain containing 3 | 0.0397194 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0387291 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0375744 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.037216 |
| CCNL1 | cyclin L1 | 0.0351061 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0351031 |
| MSN | moesin | 0.0346252 |
| MYOF | myoferlin | 0.0341804 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0339414 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0332467 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0325606 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0321534 |
| AFDN | afadin, adherens junction formation factor | 0.0306848 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0298324 |
| FLNA | filamin A, alpha | 0.0294878 |
| VMP1 | vacuole membrane protein 1 | 0.029427 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0286937 |
| MKI67 | marker of proliferation Ki-67 | 0.0261406 |
| APP | amyloid beta (A4) precursor protein | 0.025979 |
| MX1 | MX dynamin-like GTPase 1 | 0.0258937 |
| IGF2R | insulin-like growth factor 2 receptor | 0.0254702 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0252947 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0252254 |
| RUNX1 | runt-related transcription factor 1 | 0.0243045 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0232 |
| ANXA5 | annexin A5 | 0.022329 |
| FAM20C | family with sequence similarity 20, member C | 0.0222492 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0221604 |
| MLPH | melanophilin | 0.0219525 |
| ATP13A3 | ATPase type 13A3 | 0.0218902 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0213532 |
| SBF2 | SET binding factor 2 | 0.021031 |
| ZNF292 | zinc finger protein 292 | 0.0206717 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0203346 |
| WTAP | Wilms tumor 1 associated protein | 0.0199205 |
| CEP250 | centrosomal protein 250kDa | 0.0197951 |
| SPAG9 | sperm associated antigen 9 | 0.0197055 |
| THBS2 | thrombospondin 2 | 0.019163 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0188726 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0187069 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0186094 |
| DENND5A | DENN/MADD domain containing 5A | 0.0183875 |
| CORO1C | coronin, actin binding protein, 1C | 0.0181541 |
| B2M | beta-2-microglobulin | 0.0180976 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0177848 |
| XPO1 | exportin 1 | 0.0175898 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0173483 |
| TPM3 | tropomyosin 3 | 0.0172535 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0171358 |
| RUNX2 | runt-related transcription factor 2 | 0.017052 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0168196 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0167564 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0166436 |
| FHIT | fragile histidine triad | 0.0165973 |
| SYNJ2 | synaptojanin 2 | 0.0165317 |
| HMGN2 | high mobility group nucleosomal binding domain 2 | 0.0165287 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0164731 |
| THBS1 | thrombospondin 1 | 0.0164187 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0162935 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.01628 |
| XRN1 | 5'-3' exoribonuclease 1 | 0.0160741 |
| KIF4A | kinesin family member 4A | 0.0159841 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.015957 |
| RTN4 | reticulon 4 | 0.015815 |
| FMN1 | formin 1 | 0.0157431 |
| ANXA2 | annexin A2 | 0.015569 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0154697 |
| NCKAP1 | NCK-associated protein 1 | 0.0154365 |
| JMJD1C | jumonji domain containing 1C | 0.015391 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0153506 |
| CKAP5 | cytoskeleton associated protein 5 | 0.015275 |
| PRKCSH | protein kinase C substrate 80K-H | 0.0151832 |
| PLPP3 | phospholipid phosphatase 3 | 0.015064 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0150467 |
| CUL4B | cullin 4B | 0.0150365 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0149415 |
| RLIM | ring finger protein, LIM domain interacting | 0.0148529 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0147562 |
| NOTCH2 | notch 2 | 0.0146637 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0146103 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0145365 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.159149 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0900369 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0807243 |
| TMSB10 | thymosin beta 10 | -0.063773 |
| GLIS3 | GLIS family zinc finger 3 | -0.0635217 |
| HLA-B | major histocompatibility complex, class I, B | -0.0619713 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0580104 |
| HMGA2 | high mobility group AT-hook 2 | -0.0577317 |
| FTL | ferritin, light polypeptide | -0.0563134 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0536786 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0518612 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0514311 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0465188 |
| IER3 | immediate early response 3 | -0.0436861 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0415654 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0414695 |
| HLA-A | major histocompatibility complex, class I, A | -0.0392108 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0391793 |
| RPS6 | ribosomal protein S6 | -0.0377546 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0377118 |
| PTMA | prothymosin, alpha | -0.035931 |
| RPS8 | ribosomal protein S8 | -0.0354099 |
| CDH13 | cadherin 13 | -0.0348848 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0338519 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0328757 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0303045 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.0284001 |
| EFNA5 | ephrin-A5 | -0.0283941 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0283832 |
| RPS12 | ribosomal protein S12 | -0.0274736 |
| RPS23 | ribosomal protein S23 | -0.0267894 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0267301 |
| AHNAK | AHNAK nucleoprotein | -0.0257099 |
| RAI14 | retinoic acid induced 14 | -0.0255881 |
| CANX | calnexin | -0.0253975 |
| FRMPD4 | FERM and PDZ domain containing 4 | -0.0253839 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0252748 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0249674 |
| RPL35A | ribosomal protein L35a | -0.0247983 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0243231 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0242418 |
| RPL19 | ribosomal protein L19 | -0.0239921 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0233874 |
| DIAPH2 | diaphanous-related formin 2 | -0.0233362 |
| PLIN2 | perilipin 2 | -0.0229883 |
| RPLP2 | ribosomal protein, large, P2 | -0.0228522 |
| INTS6 | integrator complex subunit 6 | -0.0227253 |
| MT2A | metallothionein 2A | -0.022698 |
| ADM | adrenomedullin | -0.0222625 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0219848 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0213542 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0212863 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0206688 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0205078 |
| FBXO11 | F-box protein 11 | -0.0199386 |
| HLA-E | major histocompatibility complex, class I, E | -0.0198894 |
| CLMP | CXADR-like membrane protein | -0.0198761 |
| LOX | lysyl oxidase | -0.0198719 |
| FOXP1 | forkhead box P1 | -0.0198503 |
| RPL37A | ribosomal protein L37a | -0.0196049 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0191237 |
| RPLP1 | ribosomal protein, large, P1 | -0.0191164 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0190695 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0190437 |
| RPL36A | ribosomal protein L36a | -0.0187552 |
| NCKAP5 | NCK-associated protein 5 | -0.0186549 |
| TMEM263 | transmembrane protein 263 | -0.018292 |
| RPS14 | ribosomal protein S14 | -0.0182304 |
| RPS24 | ribosomal protein S24 | -0.0180842 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0180796 |
| STC1 | stanniocalcin 1 | -0.0180686 |
| RPS19 | ribosomal protein S19 | -0.0178808 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.017746 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0176949 |
| KRT19 | keratin 19, type I | -0.0173758 |
| LRRC7 | leucine rich repeat containing 7 | -0.0173559 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0173157 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0171929 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0171554 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0169242 |
| PHF3 | PHD finger protein 3 | -0.0169237 |
| RPL26 | ribosomal protein L26 | -0.016846 |
| RPL31 | ribosomal protein L31 | -0.0166494 |
| ASTN2 | astrotactin 2 | -0.016597 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0163965 |
| TUBB | tubulin, beta class I | -0.016369 |
| RPL37 | ribosomal protein L37 | -0.0162015 |
| RPL7A | ribosomal protein L7a | -0.0161573 |
| PRKCA | protein kinase C, alpha | -0.016074 |
| RPL9 | ribosomal protein L9 | -0.0158404 |
| RPL32 | ribosomal protein L32 | -0.0156434 |
| NRN1 | neuritin 1 | -0.0156178 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0155832 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0155703 |
| RPL36 | ribosomal protein L36 | -0.0155075 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0154167 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0153521 |
| EGFR | epidermal growth factor receptor | -0.0152699 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.015046 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0148924 |
