| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Altretamine perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Altretamine_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RBM39 | RNA binding motif protein 39 | 0.0745782 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.068529 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0669539 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0656435 |
| ZNF292 | zinc finger protein 292 | 0.063709 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.061409 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0599576 |
| ECT2 | epithelial cell transforming 2 | 0.0586377 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0555888 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0537717 |
| NUP58 | nucleoporin 58 | 0.0526992 |
| ANLN | anillin, actin binding protein | 0.0500699 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0487498 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0476573 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0472124 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0470427 |
| CENPF | centromere protein F, 350/400kDa | 0.0460239 |
| SPAG9 | sperm associated antigen 9 | 0.0454432 |
| MATR3 | matrin 3 | 0.0454014 |
| YAP1 | Yes-associated protein 1 | 0.0449833 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0446778 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0426143 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0422412 |
| NAV2 | neuron navigator 2 | 0.0408555 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0407981 |
| TPX2 | TPX2, microtubule-associated | 0.0407147 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.0405975 |
| CKAP5 | cytoskeleton associated protein 5 | 0.040555 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0398589 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0395114 |
| CD44 | CD44 molecule (Indian blood group) | 0.0391507 |
| ATP13A3 | ATPase type 13A3 | 0.0383254 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0382942 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0376081 |
| CCNL1 | cyclin L1 | 0.0375042 |
| UBAC2 | UBA domain containing 2 | 0.0373371 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0370241 |
| XPO1 | exportin 1 | 0.0365116 |
| KIF5B | kinesin family member 5B | 0.0362364 |
| SGO2 | shugoshin 2 | 0.0345433 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0342067 |
| NGLY1 | N-glycanase 1 | 0.034058 |
| RBM25 | RNA binding motif protein 25 | 0.0336981 |
| AHCTF1 | AT hook containing transcription factor 1 | 0.0331556 |
| SEPTIN7 | septin 7 | 0.0321321 |
| PHIP | pleckstrin homology domain interacting protein | 0.0315527 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0312502 |
| DHDDS | dehydrodolichyl diphosphate synthase | 0.0311702 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0310402 |
| TXNRD1 | thioredoxin reductase 1 | 0.0307654 |
| KIF4A | kinesin family member 4A | 0.0306425 |
| PDS5B | PDS5 cohesin associated factor B | 0.0303298 |
| NBAS | neuroblastoma amplified sequence | 0.0302474 |
| RNF145 | ring finger protein 145 | 0.0302189 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.030177 |
| YBX3 | Y box binding protein 3 | 0.0298869 |
| ZFAND6 | zinc finger, AN1-type domain 6 | 0.0296815 |
| SET | SET nuclear proto-oncogene | 0.0295743 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0294116 |
| PDE8A | phosphodiesterase 8A | 0.0292811 |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 | 0.0291356 |
| SETD5 | SET domain containing 5 | 0.0289862 |
| RABGAP1 | RAB GTPase activating protein 1 | 0.0288417 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.0287795 |
| MKI67 | marker of proliferation Ki-67 | 0.0286986 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0285798 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0285662 |
| FAM13A | family with sequence similarity 13, member A | 0.0284298 |
| GOLGA4 | golgin A4 | 0.0283071 |
| CLTC | clathrin, heavy chain (Hc) | 0.0281069 |
| TBC1D5 | TBC1 domain family, member 5 | 0.028051 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.028025 |
| WDR45B | WD repeat domain 45B | 0.0278955 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase | 0.0278755 |
| ANKRD36C | ankyrin repeat domain 36C | 0.027751 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0276607 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0274488 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0274441 |
| CDK17 | cyclin-dependent kinase 17 | 0.0273813 |
| KIAA1958 | KIAA1958 | 0.0272816 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.027244 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0271354 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0271125 |
| CEP295 | centrosomal protein 295kDa | 0.0270987 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0270486 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0269762 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0268805 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0268755 |
| RBM26 | RNA binding motif protein 26 | 0.0268754 |
| WDR43 | WD repeat domain 43 | 0.0265918 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0265552 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0265296 |
| HJURP | Holliday junction recognition protein | 0.0263501 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0263058 |
| HBS1L | HBS1-like translational GTPase | 0.0262145 |
| TMEM245 | transmembrane protein 245 | 0.0261762 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0260765 |
| OGA | O-GlcNAcase | 0.0260551 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0257004 |
| ATP11B | ATPase, class VI, type 11B | 0.0256587 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.161725 |
| HMGA2 | high mobility group AT-hook 2 | -0.102428 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0922951 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0875163 |
| INTS6 | integrator complex subunit 6 | -0.0790243 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0680892 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0616037 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0585796 |
| PRKCA | protein kinase C, alpha | -0.0582962 |
| AHNAK | AHNAK nucleoprotein | -0.0544519 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0542888 |
| TMSB10 | thymosin beta 10 | -0.0503941 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0503643 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0496127 |
| ANGPTL4 | angiopoietin-like 4 | -0.0448609 |
| ATM | ATM serine/threonine kinase | -0.0442783 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0437806 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0417733 |
| PRR16 | proline rich 16 | -0.0410155 |
| PCED1B | PC-esterase domain containing 1B | -0.0397541 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0384979 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0379218 |
| RAI14 | retinoic acid induced 14 | -0.0358786 |
| DST | dystonin | -0.0352841 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0350318 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0349953 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0342911 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0334786 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0332688 |
| AEBP2 | AE binding protein 2 | -0.0323953 |
| IL1RAP | interleukin 1 receptor accessory protein | -0.0317819 |
| PURA | purine-rich element binding protein A | -0.0313069 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0311266 |
| ATXN1 | ataxin 1 | -0.0305126 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0303802 |
| RPLP1 | ribosomal protein, large, P1 | -0.0298437 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) | -0.0296755 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0296261 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0289228 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -0.0285842 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0282059 |
| PODXL | podocalyxin-like | -0.0281182 |
| FMN1 | formin 1 | -0.0280636 |
| SVIL | supervillin | -0.0277349 |
| ATG7 | autophagy related 7 | -0.0273635 |
| RNF213 | ring finger protein 213 | -0.0273386 |
| PLEK2 | pleckstrin 2 | -0.0273288 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0273216 |
| NDRG1 | N-myc downstream regulated 1 | -0.0271546 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | -0.0269462 |
| EGR1 | early growth response 1 | -0.0268671 |
| FMNL2 | formin-like 2 | -0.0265674 |
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 | -0.0262453 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.026211 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0261627 |
| PCNX4 | pecanex 4 | -0.0260317 |
| GNAS | GNAS complex locus | -0.0257617 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0256723 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0255624 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | -0.0254853 |
| IGF2 | insulin-like growth factor 2 | -0.025205 |
| COL5A1 | collagen, type V, alpha 1 | -0.025125 |
| DOCK5 | dedicator of cytokinesis 5 | -0.024909 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0249087 |
| RPL35A | ribosomal protein L35a | -0.0248149 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0246343 |
| EGFR | epidermal growth factor receptor | -0.0245311 |
| ABR | active BCR-related | -0.0244973 |
| SIK2 | salt-inducible kinase 2 | -0.0244672 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0242056 |
| TVP23C-CDRT4 | TVP23C-CDRT4 readthrough | -0.023949 |
| MAP1B | microtubule-associated protein 1B | -0.023904 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0238731 |
| ASPH | aspartate beta-hydroxylase | -0.0233744 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0233056 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0232966 |
| EFNA5 | ephrin-A5 | -0.0231753 |
| TPI1 | triosephosphate isomerase 1 | -0.0230773 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0230551 |
| RPL15 | ribosomal protein L15 | -0.0227987 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0227828 |
| FSCN1 | fascin actin-bundling protein 1 | -0.022774 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0227483 |
| NLK | nemo-like kinase | -0.0227338 |
| FAM177A1 | family with sequence similarity 177, member A1 | -0.0227261 |
| THBS1 | thrombospondin 1 | -0.0226425 |
| TUT7 | terminal uridylyl transferase 7 | -0.022424 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.0224191 |
| RPL30 | ribosomal protein L30 | -0.021916 |
| SETX | senataxin | -0.0218335 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0218209 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | -0.0217053 |
| FLNB | filamin B, beta | -0.0215741 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0214184 |
| RPS17 | ribosomal protein S17 | -0.021295 |
| HLA-C | major histocompatibility complex, class I, C | -0.0212294 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | -0.0212275 |
| SMIM14 | small integral membrane protein 14 | -0.0210956 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0209033 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0208847 |
