| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Altretamine perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Altretamine_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.23032 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.195176 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.122636 |
| FN1 | fibronectin 1 | 0.100432 |
| CENPF | centromere protein F, 350/400kDa | 0.0960086 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0839171 |
| ITGA1 | integrin, alpha 1 | 0.0781369 |
| NRP1 | neuropilin 1 | 0.076172 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0758642 |
| TMEM156 | transmembrane protein 156 | 0.0720726 |
| OSMR | oncostatin M receptor | 0.0651306 |
| GLIS3 | GLIS family zinc finger 3 | 0.0627881 |
| RUNX2 | runt-related transcription factor 2 | 0.0627614 |
| ASPH | aspartate beta-hydroxylase | 0.0624913 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0611717 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0611095 |
| DST | dystonin | 0.0601781 |
| SMOX | spermine oxidase | 0.0601644 |
| VEGFA | vascular endothelial growth factor A | 0.0578412 |
| MKI67 | marker of proliferation Ki-67 | 0.0571696 |
| AHR | aryl hydrocarbon receptor | 0.0559371 |
| EREG | epiregulin | 0.0545447 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0534816 |
| RNF145 | ring finger protein 145 | 0.0530061 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0529111 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0527167 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0514711 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.050765 |
| CD44 | CD44 molecule (Indian blood group) | 0.0503029 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0494909 |
| TPR | translocated promoter region, nuclear basket protein | 0.0488396 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0476938 |
| ZNF292 | zinc finger protein 292 | 0.0476281 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0475969 |
| SMAD3 | SMAD family member 3 | 0.0472674 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0472238 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0471419 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0469679 |
| TXNRD1 | thioredoxin reductase 1 | 0.045696 |
| CANX | calnexin | 0.0451217 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0449434 |
| CAB39 | calcium binding protein 39 | 0.0444737 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0438188 |
| ETV6 | ets variant 6 | 0.0425536 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0425033 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0423124 |
| OGA | O-GlcNAcase | 0.0421052 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0420725 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0419532 |
| COPA | coatomer protein complex, subunit alpha | 0.0416257 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0410831 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0410199 |
| APP | amyloid beta (A4) precursor protein | 0.0406248 |
| ETNK1 | ethanolamine kinase 1 | 0.0402526 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0384461 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0383856 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0381621 |
| CLTC | clathrin, heavy chain (Hc) | 0.0379999 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0378084 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0373462 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0369561 |
| RBM39 | RNA binding motif protein 39 | 0.0369452 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0368453 |
| WDR26 | WD repeat domain 26 | 0.0366237 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0359428 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0355056 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0347985 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0345726 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0345267 |
| SEPTIN9 | septin 9 | 0.0342921 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0342286 |
| NUP58 | nucleoporin 58 | 0.0335848 |
| SYNJ2 | synaptojanin 2 | 0.0332706 |
| SQSTM1 | sequestosome 1 | 0.0332535 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0332359 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0330781 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0329689 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0329051 |
| PELO | pelota homolog (Drosophila) | 0.0328757 |
| PTK2 | protein tyrosine kinase 2 | 0.0327777 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0324371 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0320618 |
| RNF24 | ring finger protein 24 | 0.0320497 |
| ETV1 | ets variant 1 | 0.03202 |
| FAM20C | family with sequence similarity 20, member C | 0.031908 |
| TPM3 | tropomyosin 3 | 0.0317209 |
| ANXA5 | annexin A5 | 0.031581 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0313363 |
| NAV2 | neuron navigator 2 | 0.0313051 |
| RBM33 | RNA binding motif protein 33 | 0.0312998 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0311435 |
| ANLN | anillin, actin binding protein | 0.0310486 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0309031 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0308822 |
| MAP1B | microtubule-associated protein 1B | 0.0307867 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0306347 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0305791 |
| AOPEP | aminopeptidase O (putative) | 0.0302536 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0300019 |
| CCNL1 | cyclin L1 | 0.029987 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NRG1 | neuregulin 1 | -0.135163 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.130014 |
| MT2A | metallothionein 2A | -0.107297 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0847635 |
| EFNA5 | ephrin-A5 | -0.0750587 |
| PTMA | prothymosin, alpha | -0.0669724 |
| TMSB10 | thymosin beta 10 | -0.0642356 |
| INTS6 | integrator complex subunit 6 | -0.058708 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0560683 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0558066 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0531363 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0525464 |
| FTL | ferritin, light polypeptide | -0.0481373 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0474018 |
| NDRG1 | N-myc downstream regulated 1 | -0.0468798 |
| RPL9 | ribosomal protein L9 | -0.0421436 |
| VIM | vimentin | -0.040826 |
| RPS29 | ribosomal protein S29 | -0.0407036 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0401357 |
| RPL31 | ribosomal protein L31 | -0.0395855 |
| S100A6 | S100 calcium binding protein A6 | -0.0392989 |
| CTBP2 | C-terminal binding protein 2 | -0.0374551 |
| AEBP2 | AE binding protein 2 | -0.0372498 |
| RPL37A | ribosomal protein L37a | -0.0367604 |
| S100A10 | S100 calcium binding protein A10 | -0.0363812 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0360094 |
| CADM1 | cell adhesion molecule 1 | -0.0328184 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0320592 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0320155 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.031479 |
| RPLP1 | ribosomal protein, large, P1 | -0.0313852 |
| RPS19 | ribosomal protein S19 | -0.0310818 |
| LRRC23 | leucine rich repeat containing 23 | -0.0307942 |
| RPL35A | ribosomal protein L35a | -0.0304357 |
| RPS21 | ribosomal protein S21 | -0.0302889 |
| IER3 | immediate early response 3 | -0.0302852 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0302792 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0298839 |
| RPS24 | ribosomal protein S24 | -0.0297768 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0297552 |
| RPL12 | ribosomal protein L12 | -0.0288928 |
| DUSP6 | dual specificity phosphatase 6 | -0.0282269 |
| RPS6 | ribosomal protein S6 | -0.0279731 |
| RPS8 | ribosomal protein S8 | -0.0279622 |
| MYOF | myoferlin | -0.0278518 |
| RPLP2 | ribosomal protein, large, P2 | -0.0278161 |
| RPL19 | ribosomal protein L19 | -0.0276544 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0276409 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0276276 |
| FLNB | filamin B, beta | -0.0274833 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0266221 |
| RPLP0 | ribosomal protein, large, P0 | -0.0265203 |
| RPS27 | ribosomal protein S27 | -0.0258708 |
| RPS25 | ribosomal protein S25 | -0.0252545 |
| RPS23 | ribosomal protein S23 | -0.0251414 |
| VCL | vinculin | -0.0250401 |
| RPL34 | ribosomal protein L34 | -0.0247639 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0246776 |
| PALLD | palladin, cytoskeletal associated protein | -0.0243786 |
| HLA-B | major histocompatibility complex, class I, B | -0.0242294 |
| RPL23 | ribosomal protein L23 | -0.0242294 |
| ACTG1 | actin gamma 1 | -0.0241264 |
| POU2F2 | POU class 2 homeobox 2 | -0.024085 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0240201 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0236444 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0233733 |
| DNAH5 | dynein, axonemal, heavy chain 5 | -0.0228841 |
| RIGI | RNA sensor RIG-I | -0.0228736 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0226192 |
| RPL26 | ribosomal protein L26 | -0.0224038 |
| RASAL2 | RAS protein activator like 2 | -0.0223359 |
| RPL36 | ribosomal protein L36 | -0.0222103 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0220819 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0215009 |
| RPS11 | ribosomal protein S11 | -0.0213659 |
| MCL1 | myeloid cell leukemia 1 | -0.0211461 |
| SHC3 | SHC (Src homology 2 domain containing) transforming protein 3 | -0.0210787 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | -0.0209467 |
| CUX1 | cut-like homeobox 1 | -0.0208328 |
| RPL11 | ribosomal protein L11 | -0.020768 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0206933 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0204928 |
| NABP1 | nucleic acid binding protein 1 | -0.0202918 |
| GNAS | GNAS complex locus | -0.0202316 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0201712 |
| RPL38 | ribosomal protein L38 | -0.0198676 |
| RPL28 | ribosomal protein L28 | -0.0198422 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0196225 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | -0.0196168 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0193953 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0193785 |
| RANBP17 | RAN binding protein 17 | -0.0193208 |
| TENM4 | teneurin transmembrane protein 4 | -0.0186416 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0184098 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0183269 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0181297 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0180775 |
| RPL37 | ribosomal protein L37 | -0.0180611 |
| RPS27A | ribosomal protein S27a | -0.0180409 |
| RTN3 | reticulon 3 | -0.0179815 |
