Alveolar Bone Loss Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C0002382
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Genes

97 genes associated with the disease Alveolar Bone Loss in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ACE2 angiotensin I converting enzyme 2
ACTB actin, beta
AGER advanced glycosylation end product-specific receptor
AHR aryl hydrocarbon receptor
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
ALOX5 arachidonate 5-lipoxygenase
ALPL alkaline phosphatase, liver/bone/kidney
ALPP alkaline phosphatase, placental
ANGPT1 angiopoietin 1
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ASPN asporin
BEST1 bestrophin 1
BMP2 bone morphogenetic protein 2
CALCA calcitonin-related polypeptide alpha
CCL2 chemokine (C-C motif) ligand 2
CD36 CD36 molecule (thrombospondin receptor)
CD40LG CD40 ligand
CDK9 cyclin-dependent kinase 9
COX2
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CXCR2 chemokine (C-X-C motif) receptor 2
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DCSTAMP dendrocyte expressed seven transmembrane protein
DEFB103A defensin, beta 103A
DEFB103B defensin, beta 103B
DKK1 dickkopf WNT signaling pathway inhibitor 1
DMD dystrophin
DMP1 dentin matrix acidic phosphoprotein 1
DUSP1 dual specificity phosphatase 1
EDIL3 EGF-like repeats and discoidin I-like domains 3
ESR1 estrogen receptor 1
FBLIM1 filamin binding LIM protein 1
FOSL1 FOS-like antigen 1
GNAS GNAS complex locus
GOPC golgi-associated PDZ and coiled-coil motif containing
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
GRAP2 GRB2-related adaptor protein 2
HAVCR1 hepatitis A virus cellular receptor 1
HBEGF heparin-binding EGF-like growth factor
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
IFNG interferon, gamma
IL10 interleukin 10
IL15 interleukin 15
IL17A interleukin 17A
IL1B interleukin 1, beta
IL21 interleukin 21
IL22 interleukin 22
IL33 interleukin 33
IL6 interleukin 6
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MFGE8 milk fat globule-EGF factor 8 protein
MMP13 matrix metallopeptidase 13
MMP8 matrix metallopeptidase 8
MPO myeloperoxidase
MYD88 myeloid differentiation primary response 88
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
PCSK9 proprotein convertase subtilisin/kexin type 9
PLG plasminogen
POLDIP2 polymerase (DNA-directed), delta interacting protein 2
PPP1R42 protein phosphatase 1, regulatory subunit 42
PROS1 protein S (alpha)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTH parathyroid hormone
PTHLH parathyroid hormone-like hormone
REN renin
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SH3BP2 SH3-domain binding protein 2
SIRT1 sirtuin 1
SOST sclerostin
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
SYK spleen tyrosine kinase
TIMELESS timeless circadian clock
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TLR9 toll-like receptor 9
TM7SF2 transmembrane 7 superfamily member 2
TNF tumor necrosis factor
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TPM3 tropomyosin 3
TRAP triiodothyronine receptor auxiliary protein
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFC vascular endothelial growth factor C
ZFP36 ZFP36 ring finger protein