Ameloblastoma Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
Description A cell type benign neoplasm that has_material_basis_in odontogenic epithelium. (Human Disease Ontology, DOID_0050894)
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Genes

209 genes co-occuring with the disease Ameloblastoma in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
AMBN ameloblastin (enamel matrix protein) 2.689
BRAF B-Raf proto-oncogene, serine/threonine kinase 2.665
KRT19 keratin 19, type I 2.492
PTCH1 patched 1 2.38
CALB2 calbindin 2 2.339
KRT14 keratin 14, type I 2.33
KRT13 keratin 13, type I 2.18
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 2.166
TP53 tumor protein p53 2.164
SHH sonic hedgehog 2.151
PCNA proliferating cell nuclear antigen 2.12
ENAM enamelin 2.111
FGFR2 fibroblast growth factor receptor 2 2.067
AMTN amelotin 2.051
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 2.006
ODAM odontogenic, ameloblast asssociated 2.002
SDC1 syndecan 1 1.991
MMP9 matrix metallopeptidase 9 1.985
MMP2 matrix metallopeptidase 2 1.982
BCL2 B-cell CLL/lymphoma 2 1.981
KRT7 keratin 7, type II 1.974
KRT5 keratin 5, type II 1.973
MMP20 matrix metallopeptidase 20 1.924
KRT8 keratin 8, type II 1.924
HOXC13 homeobox C13 1.897
PDPN podoplanin 1.883
MSX2 msh homeobox 2 1.848
KRT18 keratin 18, type I 1.847
PTHLH parathyroid hormone-like hormone 1.83
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 1.809
BMP2 bone morphogenetic protein 2 1.807
DLX2 distal-less homeobox 2 1.8
SMO smoothened, frizzled class receptor 1.793
KRT10 keratin 10, type I 1.774
ING3 inhibitor of growth family, member 3 1.754
GLI1 GLI family zinc finger 1 1.736
CD68 CD68 molecule 1.734
KRT17 keratin 17, type I 1.718
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.707
CD34 CD34 molecule 1.698
ARL4C ADP-ribosylation factor-like 4C 1.696
HSPG2 heparan sulfate proteoglycan 2 1.692
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 1.686
HRAS Harvey rat sarcoma viral oncogene homolog 1.683
SOX2 SRY (sex determining region Y)-box 2 1.675
CCND1 cyclin D1 1.672
CDKN2A cyclin-dependent kinase inhibitor 2A 1.668
PITX2 paired-like homeodomain 2 1.657
TGFB1 transforming growth factor, beta 1 1.657
ENO2 enolase 2 (gamma, neuronal) 1.656
FN1 fibronectin 1 1.656
KRAS Kirsten rat sarcoma viral oncogene homolog 1.65
PXDNL peroxidasin-like 1.65
PXDN peroxidasin 1.649
AMELX amelogenin, X-linked 1.639
PTGER4 prostaglandin E receptor 4 (subtype EP4) 1.636
EWSR1 EWS RNA-binding protein 1 1.636
EGFR epidermal growth factor receptor 1.634
WNT5A wingless-type MMTV integration site family, member 5A 1.622
EGF epidermal growth factor 1.603
PTH parathyroid hormone 1.589
TIMP2 TIMP metallopeptidase inhibitor 2 1.563
SFRP2 secreted frizzled-related protein 2 1.562
MME membrane metallo-endopeptidase 1.559
ING5 inhibitor of growth family, member 5 1.547
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 1.538
RECK reversion-inducing-cysteine-rich protein with kazal motifs 1.537
PTCH2 patched 2 1.529
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 1.524
WNT1 wingless-type MMTV integration site family, member 1 1.518
MCM3 minichromosome maintenance complex component 3 1.515
DLX3 distal-less homeobox 3 1.504
JAG1 jagged 1 1.497
NCAM1 neural cell adhesion molecule 1 1.489
TUFT1 tuftelin 1 1.481
AXIN2 axin 2 1.481
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.439
MMP1 matrix metallopeptidase 1 1.436
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 1.433
KRT4 keratin 4, type II 1.431
NOTCH1 notch 1 1.43
MDK midkine (neurite growth-promoting factor 2) 1.423
MMP14 matrix metallopeptidase 14 (membrane-inserted) 1.422
GLI2 GLI family zinc finger 2 1.409
BMP4 bone morphogenetic protein 4 1.407
MMP7 matrix metallopeptidase 7 1.397
IL1A interleukin 1, alpha 1.394
ADM2 adrenomedullin 2 1.391
PTEN phosphatase and tensin homolog 1.386
ENG endoglin 1.371
FGF7 fibroblast growth factor 7 1.365
SUFU suppressor of fused homolog (Drosophila) 1.364
CTNNBIP1 catenin, beta interacting protein 1 1.362
MSX1 msh homeobox 1 1.358
ACR acrosin 1.358
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 1.347
CD44 CD44 molecule (Indian blood group) 1.336
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 1.334
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 1.329
MMP26 matrix metallopeptidase 26 1.324
FGF10 fibroblast growth factor 10 1.324
CD99L2 CD99 molecule-like 2 1.323
BIRC5 baculoviral IAP repeat containing 5 1.323
ISL1 ISL LIM homeobox 1 1.317
CD99 CD99 molecule 1.317
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 1.316
SPP1 secreted phosphoprotein 1 1.301
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.299
AMELY amelogenin, Y-linked 1.292
SPRR1A small proline-rich protein 1A 1.291
BMP7 bone morphogenetic protein 7 1.285
CDC73 cell division cycle 73 1.283
RUNX2 runt-related transcription factor 2 1.282
HMGB2 high mobility group box 2 1.278
ERAS ES cell expressed Ras 1.277
COMMD3-BMI1 COMMD3-BMI1 readthrough 1.276
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 1.273
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 1.272
BMI1 BMI1 proto-oncogene, polycomb ring finger 1.271
WNT3A wingless-type MMTV integration site family, member 3A 1.268
IBSP integrin-binding sialoprotein 1.268
PECAM1 platelet/endothelial cell adhesion molecule 1 1.264
FGF2 fibroblast growth factor 2 (basic) 1.263
KITLG KIT ligand 1.259
FGF8 fibroblast growth factor 8 (androgen-induced) 1.258
NOTCH2 notch 2 1.257
FGF3 fibroblast growth factor 3 1.254
INCA1 inhibitor of CDK, cyclin A1 interacting protein 1 1.248
ING1 inhibitor of growth family, member 1 1.246
IVL involucrin 1.24
FGF22 fibroblast growth factor 22 1.238
FGF16 fibroblast growth factor 16 1.236
GLI3 GLI family zinc finger 3 1.236
TERT telomerase reverse transcriptase 1.231
FGF17 fibroblast growth factor 17 1.231
FGF4 fibroblast growth factor 4 1.227
FGF6 fibroblast growth factor 6 1.221
FGF20 fibroblast growth factor 20 1.219
IL6 interleukin 6 1.215
FGF18 fibroblast growth factor 18 1.213
FGF5 fibroblast growth factor 5 1.213
AXIN1 axin 1 1.212
TP63 tumor protein p63 1.212
NGFR nerve growth factor receptor 1.21
USP6 ubiquitin specific peptidase 6 1.21
TIMP1 TIMP metallopeptidase inhibitor 1 1.207
LEF1 lymphoid enhancer-binding factor 1 1.205
FGF9 fibroblast growth factor 9 1.204
POU5F1 POU class 5 homeobox 1 1.2
WNT10A wingless-type MMTV integration site family, member 10A 1.197
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 1.194
DSPP dentin sialophosphoprotein 1.191
FASLG Fas ligand (TNF superfamily, member 6) 1.188
RIPOR3 RIPOR family member 3 1.188
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 1.182
ACP4 acid phosphatase 4 1.182
CRTC1 CREB regulated transcription coactivator 1 1.18
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.169
SNAI1 snail family zinc finger 1 1.164
CD1A CD1a molecule 1.16
TNF tumor necrosis factor 1.159
CORO7-PAM16 CORO7-PAM16 readthrough 1.156
ING4 inhibitor of growth family, member 4 1.156
SOX10 SRY (sex determining region Y)-box 10 1.156
FRZB frizzled-related protein 1.151
WNT2 wingless-type MMTV integration site family member 2 1.151
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.143
RUNX1 runt-related transcription factor 1 1.14
HDGF hepatoma-derived growth factor 1.138
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.125
BARX1 BARX homeobox 1 1.118
CD1E CD1e molecule 1.118
P3H3 prolyl 3-hydroxylase 3 1.116
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) 1.112
KLK4 kallikrein-related peptidase 4 1.105
FGF13 fibroblast growth factor 13 1.103
CD1B CD1b molecule 1.1
JAG2 jagged 2 1.1
DLX4 distal-less homeobox 4 1.097
CDH17 cadherin 17, LI cadherin (liver-intestine) 1.096
MSH3 mutS homolog 3 1.096
STK19 serine/threonine kinase 19 1.094
CDH12 cadherin 12, type 2 (N-cadherin 2) 1.092
CCDC191 coiled-coil domain containing 191 1.09
CCN2 cellular communication network factor 2 1.087
ACP5 acid phosphatase 5, tartrate resistant 1.085
HCLS1 hematopoietic cell-specific Lyn substrate 1 1.082
NOTCH4 notch 4 1.08
CTTN cortactin 1.078
KRT20 keratin 20, type I 1.074
WNT8B wingless-type MMTV integration site family, member 8B 1.069
COL8A1 collagen, type VIII, alpha 1 1.066
ALB albumin 1.065
NOTCH3 notch 3 1.065
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 1.064
SNAI2 snail family zinc finger 2 1.059
SACK1H scaffolding CK1 anchoring protein H 1.047
BSG basigin (Ok blood group) 1.045
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 1.032
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 1.026
SS18 synovial sarcoma translocation, chromosome 18 1.025
GSK3B glycogen synthase kinase 3 beta 1.02
CD1C CD1c molecule 1.019
PAX9 paired box 9 1.019
NTRK3 neurotrophic tyrosine kinase, receptor, type 3 1.015
ADM5 adrenomedullin 5 (putative) 1.013
PXN paxillin 1.012
NNMT nicotinamide N-methyltransferase 1.005
ABT1 activator of basal transcription 1 1.0