Ameloblastoma Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A cell type benign neoplasm that has_material_basis_in odontogenic epithelium. (Human Disease Ontology, DOID_0050894)
External Link https://www.disgenet.org/browser/0/1/0/C0002448
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Genes

164 genes associated with the disease Ameloblastoma in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ACTB actin, beta
AKT1 v-akt murine thymoma viral oncogene homolog 1
AMBN ameloblastin (enamel matrix protein)
AMELX amelogenin, X-linked
AMELY amelogenin, Y-linked
APC adenomatous polyposis coli
ARHGAP24 Rho GTPase activating protein 24
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
AXIN1 axin 1
AXIN2 axin 2
BAMBI BMP and activin membrane-bound inhibitor
BCL2 B-cell CLL/lymphoma 2
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BGN biglycan
BMP2 bone morphogenetic protein 2
BMP4 bone morphogenetic protein 4
BRAF B-Raf proto-oncogene, serine/threonine kinase
C1ORF228 chromosome 1 open reading frame 228
CADM1 cell adhesion molecule 1
CALB2 calbindin 2
CASP8 caspase 8, apoptosis-related cysteine peptidase
CCN2 cellular communication network factor 2
CCND1 cyclin D1
CD34 CD34 molecule
CD44 CD44 molecule (Indian blood group)
CD68 CD68 molecule
CDH18 cadherin 18, type 2
CDK2AP2 cyclin-dependent kinase 2 associated protein 2
CDK4 cyclin-dependent kinase 4
CDKN2A cyclin-dependent kinase inhibitor 2A
CKAP4 cytoskeleton-associated protein 4
COX2
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CXCL8 chemokine (C-X-C motif) ligand 8
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1)
DDR1 discoidin domain receptor tyrosine kinase 1
DDR2 discoidin domain receptor tyrosine kinase 2
EBNA1BP2 EBNA1 binding protein 2
EGFR epidermal growth factor receptor
ENAM enamelin
EPHB4 EPH receptor B4
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ERBB4 erb-b2 receptor tyrosine kinase 4
EWSR1 EWS RNA-binding protein 1
EZR ezrin
FGF10 fibroblast growth factor 10
FGF2 fibroblast growth factor 2 (basic)
FGF3 fibroblast growth factor 3
FGF7 fibroblast growth factor 7
FGFR1 fibroblast growth factor receptor 1
FGFR2 fibroblast growth factor receptor 2
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FOS FBJ murine osteosarcoma viral oncogene homolog
GGT1 gamma-glutamyltransferase 1
GGTLC3 gamma-glutamyltransferase light chain 3
GLI1 GLI family zinc finger 1
GNAS GNAS complex locus
GPC1 glypican 1
GPC3 glypican 3
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HPSE heparanase
HRAS Harvey rat sarcoma viral oncogene homolog
HSPG2 heparan sulfate proteoglycan 2
IBSP integrin-binding sialoprotein
IL1A interleukin 1, alpha
IL6 interleukin 6
IL9 interleukin 9
ING1 inhibitor of growth family, member 1
ING2 inhibitor of growth family, member 2
ING5 inhibitor of growth family, member 5
ISL1 ISL LIM homeobox 1
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
JAG1 jagged 1
JAG2 jagged 2
KMT2D lysine (K)-specific methyltransferase 2D
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT14 keratin 14, type I
KRT19 keratin 19, type I
LAMTOR2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial)
MAP2K7 mitogen-activated protein kinase kinase 7
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MARCH10 membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MIB1 mindbomb E3 ubiquitin protein ligase 1
MKI67 marker of proliferation Ki-67
MLH1 mutL homolog 1
MMP1 matrix metallopeptidase 1
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MOGS mannosyl-oligosaccharide glucosidase
MSC musculin
MSH2 mutS homolog 2
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYC v-myc avian myelocytomatosis viral oncogene homolog
NOTCH1 notch 1
NOTCH2 notch 2
NOTCH3 notch 3
NOTCH4 notch 4
NR0B1 nuclear receptor subfamily 0, group B, member 1
PCNA proliferating cell nuclear antigen
PDGFA platelet-derived growth factor alpha polypeptide
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDPN podoplanin
PI3 peptidase inhibitor 3, skin-derived
POSTN periostin, osteoblast specific factor
POU5F1 POU class 5 homeobox 1
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
PTCH1 patched 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTHLH parathyroid hormone-like hormone
QPCT glutaminyl-peptide cyclotransferase
RABEPK Rab9 effector protein with kelch motifs
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RBM10 RNA binding motif protein 10
RECK reversion-inducing-cysteine-rich protein with kazal motifs
RPE65 retinal pigment epithelium-specific protein 65kDa
RPP14 ribonuclease P/MRP 14kDa subunit
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RPSA ribosomal protein SA
S100A9 S100 calcium binding protein A9
SACK1H scaffolding CK1 anchoring protein H
SDC1 syndecan 1
SDC2 syndecan 2
SF3B6 splicing factor 3b, subunit 6, 14kDa
SHH sonic hedgehog
SMO smoothened, frizzled class receptor
SOX2 SRY (sex determining region Y)-box 2
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SS18 synovial sarcoma translocation, chromosome 18
SSX2 synovial sarcoma, X breakpoint 2
SSX2B synovial sarcoma, X breakpoint 2B
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
SUB1 SUB1 homolog (S. cerevisiae)
SUFU suppressor of fused homolog (Drosophila)
SYT1 synaptotagmin I
TGFB2 transforming growth factor, beta 2
TIMP2 TIMP metallopeptidase inhibitor 2
TNC tenascin C
TNF tumor necrosis factor
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TP53 tumor protein p53
TP63 tumor protein p63
TP73 tumor protein p73
TUFT1 tuftelin 1
UVRAG UV radiation resistance associated
VEGFA vascular endothelial growth factor A
VIM vimentin
WNT1 wingless-type MMTV integration site family, member 1
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
ZEB1 zinc finger E-box binding homeobox 1