Amifostine Gene Set

Dataset CTD Gene-Chemical Interactions
Category physical interactions
Type chemical
Description An organic thiophosphate that is the S-phospho derivative of 2-[(3-aminopropyl)amino]ethanethiol. A prodrug for the free thiol, WR-1065, which is used as a cytoprotectant in cancer chemotherapy and radiotherapy. (Chemical Entities of Biological Interest Ontology, CHEBI_2636)
External Link http://ctdbase.org/detail.go?type=chem&acc=D004999
Similar Terms
Downloads & Tools

Genes

11 genes/proteins interacting with the chemical Amifostine from the curated CTD Gene-Chemical Interactions dataset.

Symbol Name
CASP3 caspase 3, apoptosis-related cysteine peptidase
CDK1 cyclin-dependent kinase 1
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
IL6 interleukin 6
MAPK14 mitogen-activated protein kinase 14
MPO myeloperoxidase
MYL2 myosin, light chain 2, regulatory, cardiac, slow
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
PCNA proliferating cell nuclear antigen
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
TP53 tumor protein p53