Amlodipine Gene Set

Dataset CTD Gene-Chemical Interactions
Category physical interactions
Type chemical
Description A fully substituted dialkyl 1,4-dihydropyridine-3,5-dicarboxylate derivative, which is used for the treatment of hypertension, chronic stable angina and confirmed or suspected vasospastic angina. (Chemical Entities of Biological Interest Ontology, CHEBI_2668)
External Link http://ctdbase.org/detail.go?type=chem&acc=D017311
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Genes

40 genes/proteins interacting with the chemical Amlodipine from the curated CTD Gene-Chemical Interactions dataset.

Symbol Name
ADIPOQ adiponectin, C1Q and collagen domain containing
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP7 caspase 7, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CCND1 cyclin D1
CCNE1 cyclin E1
CDK2 cyclin-dependent kinase 2
CDK4 cyclin-dependent kinase 4
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CRP C-reactive protein, pentraxin-related
CTSD cathepsin D
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DRD1 dopamine receptor D1
DRD2 dopamine receptor D2
EDN1 endothelin 1
GAL galanin/GMAP prepropeptide
GSR glutathione reductase
GUSB glucuronidase, beta
HSPD1 heat shock 60kDa protein 1 (chaperonin)
ICAM1 intercellular adhesion molecule 1
INS insulin
JAK2 Janus kinase 2
LEP leptin
MTF1 metal-regulatory transcription factor 1
NOS3 nitric oxide synthase 3 (endothelial cell)
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
RB1 retinoblastoma 1
REN renin
RETN resistin
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SMAD2 SMAD family member 2
SMAD4 SMAD family member 4
SOD1 superoxide dismutase 1, soluble
TGFB1 transforming growth factor, beta 1
TNF tumor necrosis factor