Amphetamine Abuse Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A substance abuse that involves the recurring use of amphetamines despite negative consequences. (Human Disease Ontology, DOID_670)
External Link https://www.disgenet.org/browser/0/1/0/C0236807
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Genes

74 genes associated with the disease Amphetamine Abuse in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ACHE acetylcholinesterase (Yt blood group)
ACSL6 acyl-CoA synthetase long-chain family member 6
ADORA2A adenosine A2a receptor
AK5 adenylate kinase 5
AKT1 v-akt murine thymoma viral oncogene homolog 1
AOAH acyloxyacyl hydrolase (neutrophil)
ARRB2 arrestin, beta 2
ASTN2 astrotactin 2
BDNF brain-derived neurotrophic factor
CCHCR1 coiled-coil alpha-helical rod protein 1
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDH13 cadherin 13
COL28A1 collagen, type XXVIII, alpha 1
COMT catechol-O-methyltransferase
CSMD1 CUB and Sushi multiple domains 1
CUBN cubilin (intrinsic factor-cobalamin receptor)
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
DCSTAMP dendrocyte expressed seven transmembrane protein
DRD1 dopamine receptor D1
DRD2 dopamine receptor D2
DRD3 dopamine receptor D3
DRD4 dopamine receptor D4
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
FHIT fragile histidine triad
FKBP15 FK506 binding protein 15, 133kDa
FOS FBJ murine osteosarcoma viral oncogene homolog
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2
GDNF glial cell derived neurotrophic factor
GRM2 glutamate receptor, metabotropic 2
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
HS3ST4 heparan sulfate (glucosamine) 3-O-sulfotransferase 4
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
LARGE like-glycosyltransferase
LINGO2 leucine rich repeat and Ig domain containing 2
MAP2K5 mitogen-activated protein kinase kinase 5
MARC1 mitochondrial amidoxime reducing component 1
MARC2 mitochondrial amidoxime reducing component 2
MYO5B myosin VB
NOS1 nitric oxide synthase 1 (neuronal)
NPY1R neuropeptide Y receptor Y1
NRG1 neuregulin 1
OPRM1 opioid receptor, mu 1
PCOLCE2 procollagen C-endopeptidase enhancer 2
PDE4B phosphodiesterase 4B, cAMP-specific
PDE4D phosphodiesterase 4D, cAMP-specific
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PDYN prodynorphin
PICK1 protein interacting with PRKCA 1
PLAT plasminogen activator, tissue
POU5F1 POU class 5 homeobox 1
PRDM2 PR domain containing 2, with ZNF domain
PRKG1 protein kinase, cGMP-dependent, type I
PROKR2 prokineticin receptor 2
PSD3 pleckstrin and Sec7 domain containing 3
RALY RALY heterogeneous nuclear ribonucleoprotein
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RGS17 regulator of G-protein signaling 17
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SGCZ sarcoglycan, zeta
SH3RF3 SH3 domain containing ring finger 3
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
SMYD3 SET and MYND domain containing 3
SNCA synuclein, alpha (non A4 component of amyloid precursor)
TRPM3 transient receptor potential cation channel, subfamily M, member 3
USP48 ubiquitin specific peptidase 48
ZNF385D zinc finger protein 385D
ZNF423 zinc finger protein 423