| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Amsacrine perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Amsacrine_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.236141 |
| IGF2 | insulin-like growth factor 2 | 0.228697 |
| VCL | vinculin | 0.204999 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.143466 |
| TLE4 | transducin-like enhancer of split 4 | 0.108563 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.107663 |
| EXT1 | exostosin glycosyltransferase 1 | 0.104051 |
| NRG1 | neuregulin 1 | 0.0864274 |
| FMN1 | formin 1 | 0.0848268 |
| LPIN1 | lipin 1 | 0.0753605 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0715876 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.070096 |
| TRIB2 | tribbles pseudokinase 2 | 0.0692064 |
| PLAT | plasminogen activator, tissue | 0.0686432 |
| PRKCA | protein kinase C, alpha | 0.063024 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0602432 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0590803 |
| SEPTIN9 | septin 9 | 0.0589857 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0569973 |
| ANTXR1 | anthrax toxin receptor 1 | 0.0561302 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0546581 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0530654 |
| RNF213 | ring finger protein 213 | 0.0525753 |
| FAM13A | family with sequence similarity 13, member A | 0.0514327 |
| LSAMP | limbic system-associated membrane protein | 0.0504081 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0502025 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0498761 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0490253 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0484907 |
| FERMT2 | fermitin family member 2 | 0.0481291 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0472251 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0467238 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.0463921 |
| RIGI | RNA sensor RIG-I | 0.0459119 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0454995 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | 0.0449496 |
| MEIS2 | Meis homeobox 2 | 0.0449212 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | 0.0435935 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0435816 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.043566 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0433361 |
| AUTS2 | autism susceptibility candidate 2 | 0.0433165 |
| THBS1 | thrombospondin 1 | 0.0433113 |
| MED13 | mediator complex subunit 13 | 0.0423814 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0420028 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0409593 |
| TLK2 | tousled-like kinase 2 | 0.0406952 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0402547 |
| FNDC3B | fibronectin type III domain containing 3B | 0.039802 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0396562 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | 0.0395227 |
| SF3B3 | splicing factor 3b, subunit 3, 130kDa | 0.0391932 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | 0.039085 |
| MSI2 | musashi RNA-binding protein 2 | 0.03876 |
| FAM107B | family with sequence similarity 107, member B | 0.0386315 |
| PRKCE | protein kinase C, epsilon | 0.0385957 |
| RAD51B | RAD51 paralog B | 0.0381499 |
| MYO1E | myosin IE | 0.0381489 |
| HELZ | helicase with zinc finger | 0.037721 |
| CDH13 | cadherin 13 | 0.0377071 |
| TPM1 | tropomyosin 1 (alpha) | 0.037584 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0375313 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0371779 |
| KIAA1217 | KIAA1217 | 0.036881 |
| ATXN1 | ataxin 1 | 0.0366671 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0363554 |
| MED13L | mediator complex subunit 13-like | 0.0358473 |
| ANKS1A | ankyrin repeat and sterile alpha motif domain containing 1A | 0.0356898 |
| HIP1 | huntingtin interacting protein 1 | 0.0351913 |
| GLCCI1 | glucocorticoid induced 1 | 0.0351451 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.035072 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0348962 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | 0.0344494 |
| FNBP1 | formin binding protein 1 | 0.034439 |
| RGS5 | regulator of G-protein signaling 5 | 0.0344004 |
| MCL1 | myeloid cell leukemia 1 | 0.0340683 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0340288 |
| SMAD3 | SMAD family member 3 | 0.033837 |
| DNMBP | dynamin binding protein | 0.0333297 |
| PCM1 | pericentriolar material 1 | 0.0333069 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0332823 |
| SLITRK6 | SLIT and NTRK-like family, member 6 | 0.0327874 |
| GLG1 | golgi glycoprotein 1 | 0.0322057 |
| NCOR2 | nuclear receptor corepressor 2 | 0.032205 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0321562 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0320564 |
| TPM4 | tropomyosin 4 | 0.0319099 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 0.0317453 |
| CRH | corticotropin releasing hormone | 0.0316962 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0314627 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0314207 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0314206 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0313772 |
| SMYD3 | SET and MYND domain containing 3 | 0.0313064 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.031004 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.03097 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0308437 |
| STK38L | serine/threonine kinase 38 like | 0.0307892 |
| AHR | aryl hydrocarbon receptor | 0.0304852 |
| SIK2 | salt-inducible kinase 2 | 0.0303374 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0656586 |
| RPS24 | ribosomal protein S24 | -0.0510198 |
| RPL34 | ribosomal protein L34 | -0.0495619 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0473638 |
| RPS19 | ribosomal protein S19 | -0.0467282 |
| RPLP1 | ribosomal protein, large, P1 | -0.0463071 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.045819 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | -0.0432237 |
| RPL35A | ribosomal protein L35a | -0.0410916 |
| RPL31 | ribosomal protein L31 | -0.0402326 |
| RPS6 | ribosomal protein S6 | -0.0393688 |
| RPLP0 | ribosomal protein, large, P0 | -0.0383529 |
| SYT1 | synaptotagmin I | -0.0370985 |
| FTL | ferritin, light polypeptide | -0.0359212 |
| RPS17 | ribosomal protein S17 | -0.0356779 |
| PTMA | prothymosin, alpha | -0.0349934 |
| SPAG9 | sperm associated antigen 9 | -0.0335507 |
| VIM | vimentin | -0.0329576 |
| RPL36 | ribosomal protein L36 | -0.0325904 |
| PCDH9 | protocadherin 9 | -0.0313467 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0313224 |
| CADM2 | cell adhesion molecule 2 | -0.0306327 |
| RPL27 | ribosomal protein L27 | -0.0283992 |
| RPS12 | ribosomal protein S12 | -0.0276254 |
| MMP12 | matrix metallopeptidase 12 | -0.0274411 |
| S100A10 | S100 calcium binding protein A10 | -0.0266619 |
| CEP95 | centrosomal protein 95kDa | -0.0264405 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.026427 |
| MTAP | methylthioadenosine phosphorylase | -0.0259435 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0256088 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | -0.0254636 |
| CDK6 | cyclin-dependent kinase 6 | -0.0246041 |
| RPS27L | ribosomal protein S27-like | -0.024563 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.0244636 |
| SVIL | supervillin | -0.0243391 |
| RPL7 | ribosomal protein L7 | -0.0239359 |
| PPME1 | protein phosphatase methylesterase 1 | -0.0235597 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0232231 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0227983 |
| RPL32 | ribosomal protein L32 | -0.0227056 |
| RPS5 | ribosomal protein S5 | -0.0225601 |
| MIB1 | mindbomb E3 ubiquitin protein ligase 1 | -0.0219778 |
| RPLP2 | ribosomal protein, large, P2 | -0.0215365 |
| DEK | DEK proto-oncogene | -0.0214755 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0214719 |
| MATR3 | matrin 3 | -0.0213893 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0210524 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.020919 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0207204 |
| RPL36AL | ribosomal protein L36a-like | -0.0206236 |
| H3-3B | H3.3 histone B | -0.020537 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.0204266 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0202098 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0200115 |
| RACK1 | receptor for activated C kinase 1 | -0.0199851 |
| YBX3 | Y box binding protein 3 | -0.0198075 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0198017 |
| PSMD12 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 | -0.019629 |
| RPS16 | ribosomal protein S16 | -0.0195676 |
| COL1A1 | collagen, type I, alpha 1 | -0.0195034 |
| TUBB | tubulin, beta class I | -0.019359 |
| TMSB4X | thymosin beta 4, X-linked | -0.0192739 |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit | -0.0191873 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0190686 |
| UBC | ubiquitin C | -0.0188752 |
| LAMB3 | laminin, beta 3 | -0.0188585 |
| UBA52 | ubiquitin A-52 residue ribosomal protein fusion product 1 | -0.01881 |
| KIF21A | kinesin family member 21A | -0.0187973 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | -0.0187707 |
| SEPTIN2 | septin 2 | -0.0183753 |
| CTSD | cathepsin D | -0.0181933 |
| RPS8 | ribosomal protein S8 | -0.0181809 |
| VPS35 | vacuolar protein sorting 35 homolog (S. cerevisiae) | -0.0181458 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | -0.018107 |
| RFX7 | regulatory factor X, 7 | -0.0179679 |
| FN1 | fibronectin 1 | -0.0178768 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0178219 |
| NUP214 | nucleoporin 214kDa | -0.0177495 |
| NIPSNAP2 | nipsnap homolog 2 | -0.0174376 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0173675 |
| SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 | -0.0173142 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | -0.0173074 |
| CHMP2B | charged multivesicular body protein 2B | -0.0172698 |
| AQR | aquarius intron-binding spliceosomal factor | -0.0172397 |
| SIAH1 | siah E3 ubiquitin protein ligase 1 | -0.0171836 |
| GAB2 | GRB2-associated binding protein 2 | -0.0171648 |
| RPL19 | ribosomal protein L19 | -0.0170529 |
| PSMB4 | proteasome (prosome, macropain) subunit, beta type, 4 | -0.0169544 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0168431 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0168328 |
| RPL30 | ribosomal protein L30 | -0.016608 |
| RPL23 | ribosomal protein L23 | -0.0165772 |
| TARS1 | threonyl-tRNA synthetase 1 | -0.0165528 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0165483 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | -0.016439 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0164229 |
| MYLK | myosin light chain kinase | -0.0164057 |
| RPS11 | ribosomal protein S11 | -0.0163476 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.016255 |
| SESN1 | sestrin 1 | -0.016223 |
